J
John M. Pezzuto
Researcher at Long Island University
Publications - 599
Citations - 38474
John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.
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Natural modulators of estrogen biosynthesis and function as chemopreventive agents.
TL;DR: Some agents currently in use or under development for treatment or prevention of breast cancer, as well as strategies for the discovery of natural product modulators of estrogen biosynthesis and function are described.
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Resveratrol: a whiff that induces a biologically specific tsunami.
TL;DR: Commentary to: Effects of Resveratrol on Gene Expression in Renal Cell Carcinoma Ting Shi, Louis S. Liou, Provash Sadhukhan, Zhong-Hui Duan, Andrew C. Novick, John G. Hissong, Alexandru Almasan and Joseph A. DiDonato
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Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2.
Dae Sik Jang,Muriel Cuendet,Bao-Ning Su,Steven Totura,Soedarsono Riswan,Harry H. S. Fong,John M. Pezzuto,A. Douglas Kinghorn +7 more
TL;DR: A new dibenzylbutyrolactone lignan, (2 R,3 R)-5'-methoxyguayarol (1), was isolated from an EtOAc-soluble extract of the seeds of Hernandia ovigera using an in vitro activity-guided fractionation procedure based on the inhibition of cyclooxygenase-2.
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Neoflavonoids and tetrahydroquinolones as possible cancer chemopreventive agents.
Suaib Luqman,Abha Meena,Pragya Singh,Tamara P. Kondratyuk,Laura Marler,John M. Pezzuto,Arvind S. Negi +6 more
TL;DR: Investigation into the actions of neoflavonoids and tetrahydroquinolones, especially those related to the NFκB signaling pathway, aromatase inhibition, induction of quinone reductase 1 expression, and in vivo studies could provide new insights into the cancer chemopreventive ability of these molecules.
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Evaluation of the mutagenic potential of endod (Phytolacca dodecandra), a molluscicide of potential value for the control of schistosomiasis.
TL;DR: Subject to the results of future safety assessment, endod remains a viable candidate as a useful molluscicide.