J
John M. Pezzuto
Researcher at Long Island University
Publications - 599
Citations - 38474
John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.
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Journal ArticleDOI
Black Cohosh (Cimicifuga racemosa L.) Protects against Menadione-Induced DNA Damage through Scavenging of Reactive Oxygen Species: Bioassay-Directed Isolation and Characterization of Active Principles
Joanna E. Burdette,Shao-Nong Chen,Zhi Zhen Lu,Haiyan Xu,Bethany E. Perez White,Daniel S. Fabricant,Jianghua Liu,Harry H. S. Fong,Norman R. Farnsworth,Andreas I. Constantinou,Richard B. van Breemen,John M. Pezzuto,Judy L. Bolton +12 more
TL;DR: Analysis of methanol extracts suggests that black cohosh can protect against cellular DNA damage caused by reactive oxygen species by acting as antioxidants.
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Malaria remedies of the Kenyah of the Apo Kayan, East Kalimantan, Indonesian Borneo: a quantitative assessment of local consensus as an indicator of biological efficacy.
Danna J. Leaman,J. T. Arnason,Razali Yusuf,Harini Sangat-Roemantyo,Herwasono Soedjito,Cindy K. Angerhofer,John M. Pezzuto +6 more
TL;DR: A quantitative analysis of the relationship between a 'local importance value' index for each malaria remedy (IVmal) and inhibition of cultured Plasmodium falciparum by ethanolic extracts supports the hypothesis that the degree of local consensus about a given remedy is a good indicator of its potential biological efficacy.
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Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay.
Bao-Ning Su,Eun Jung Park,Jose Schunke Vigo,James G. Graham,Fernando Cabieses,Harry H. S. Fong,John M. Pezzuto,A. Douglas Kinghorn +7 more
TL;DR: Activity-guided fractionation of an EtOAc-soluble extract of the leaves of Muntingia calabura collected in Peru resulted in the isolation of a flavanone with an unsubstituted B-ring, (2R,3R)-7-methoxy-3,5,8-trihydroxyflavanone (5), as well as 24 known compounds, which were mainly flavanones and flavones.
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Koenoline, a further cytotoxic carbazole alkaloid from Murraya koenigii
TL;DR: Koenoline, a carbazole alkaloid, has been isolated from the root bark of Murraya koenigii for the first time as a natural product and exhibited cytotoxic activity against the KB cell-culture test system.
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Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats.
Andreas I. Constantinou,Daniel D. Lantvit,Michael E. Hawthorne,Xiaoying Xu,Richard B. van Breemen,John M. Pezzuto +5 more
TL;DR: Results show that daidzein and SPI (with normal or low levels of isoflavones) are effective inhibitors of DMBA-induced mammary tumors in adult rats.