J
John M. Pezzuto
Researcher at Long Island University
Publications - 599
Citations - 38474
John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.
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An International Collaborative Program To Discover New Drugs from Tropical Biodiversity of Vietnam and Laos
Djaja Djendoel Soejarto,John M. Pezzuto,Harry H. S. Fong,Ghee Teng Tan,Hongjie Zhang,Pamela A. Tamez,Zeynep Aydogmus,Nguyen Quyet Chien,Scott G. Franzblau,Charlotte Gyllenhaal,Jacinto C. Regalado,Nguyen Van Hung,Vu Dinh Hoang,Nguyen Tien Hiep,Le Thi Xuan,Nong Van Hai,Nguyen Manh Cuong,Truong Quang Bich,Phan Ke Loc,Bui Minh Vu,Boun Hoong Southavong,Kongmany Sydara,Somsanith Bouamanivong,Melanie J. O'Neill,Jane Lewis,Gregg Dietzman +25 more
TL;DR: The results of the drug discovery effort to date indicate that tropical plant diversity of Vietnam and Laos unquestionably harbors biologically active chemical entities, which, through further research, may eventually yield candidates for drug development.
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Novel Bioactive Steroidal Alkaloids from Pachysandra procumbens
TL;DR: In this paper, a new substitution pattern was proposed for the substitution pattern of Pachysandra procumbens and four new steroidal alkaloids, including (+)-(20S)-3-(benzoylamino)-20-(dimethylamino),5α-pregn-2-en-4β-ol.
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Anti-inflammatory triterpenes from the apical bud of Gardenia sootepensis
Ui Joung Youn,Eun-Jung Park,Tamara P. Kondratyuk,Tawanun Sripisut,Surat Laphookhieo,John M. Pezzuto,Leng Chee Chang +6 more
TL;DR: Four new cycloartane triterpenes, sootepins F-I, along with four known derivatives, were isolated for cancer chemopreventive potential based on their ability to inhibit nitric oxide production and tumor necrosis factor-alpha-induced nuclear factor kappa activity.
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Cytotoxic ent-kaurene diterpenoids from three Isodon species.
Han-Dong Sun,Zhong-Wen Lin,Fang-Di Niu,Long-Ze Lin,Heebyung Chai,John M. Pezzuto,Geoffrey A. Cordell +6 more
TL;DR: The structure determination of loxothyrin A, and the unambiguous NMR spectral assignments of the known compounds were made by a combination of 1D and 2D NMR techniques and computer modelling calculations.