J
John M. Pezzuto
Researcher at Long Island University
Publications - 599
Citations - 38474
John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.
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Journal ArticleDOI
Minor Withanolides from Physalis philadelphica: Structures, Quinone Reductase Induction Activities, and Liquid Chromatography (LC)-MS-MS Investigation as Artifacts
Jian Qiao Gu,Wenkui Li,Young Hwa Kang,Bao Ning Su,Harry H. S. Fong,Richard B. van Breemen,John M. Pezzuto,A. Douglas Kinghorn +7 more
TL;DR: This promising lead compound was reisolated in gram quantities for in vivo biological testing and found in the fresh fruits of P. philadelphica by LC-MS-MS analysis at a concentration of 143+/-4.53 ppb.
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Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza.
Sudarat Homhual,Hongjie Zhang,Nuntavan Bunyapraphatsara,Tamara P. Kondratyuk,Bernard D. Santarsiero,Andrew D. Mesecar,Angkana Herunsalee,Wongsatit Chaukul,John M. Pezzuto,Harry H. S. Fong +9 more
TL;DR: A new cyclic 4-hydroxy-dithiosulfonate, bruguiesulfurol, as well as two known 4-Hydroxydithiolane 1-oxides, burgierol and isobrugierol, were isolated from the flowers of Bruguiera gymnorrhiza and their structures were determined by spectral data and that of compound 1 was confirmed by X-ray crystallographic analysis.
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Sesquiterpene Lactones and Thymol Esters from Vicoa pentanema
Jaber S. Mossa,Farouk S. El-Feraly,Ilias Muhammad,Kyaw Zaw,Zakaria H. Mbwambo,John M. Pezzuto,Harry H. S. Fong +6 more
TL;DR: The aerial parts of Vicoa pentanema yielded four new sesquiterpene lactones, namely, 10α-hydroxy-14H-inuviscolide (1), 4α,5α-epoxy-10α,11β,13H, 14H-1-epi-inviscolides 3-β-d-glucoside (2), 2α-O-acety...
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An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development
Djaja D. Soejarto,Charlotte Gyllenhaal,Marian R. Kadushin,Marian R. Kadushin,B. Southavong,Kongmany Sydara,Somsanith Bouamanivong,M. Xaiveu,Hongjie Zhang,Scott G. Franzblau,Ghee Teng Tan,John M. Pezzuto,M. C. Riley,Bethany G. Elkington,Donald P. Waller +14 more
TL;DR: Ethnobotanical survey has demonstrated the richness of plant-based traditional medicine of Lao PDR, taxonomically and therapeutically, and yielded a series of new bioactive compounds against the diseases of cancer and malaria.
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Pentacyclic triterpenes and naphthoquinones from Euclea divinorum
TL;DR: In this paper, the structures were assigned on the basis of spectral and chemical studies and the compounds were evaluated for their cytotoxic activity for Euclea divinorum, including lupeol, lupene, betulin, 7-methyljuglone, isodiospyrin, shinalone, catechin and 3β-(5-hydroxyferuloyl)lup-20(30)-ene.