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John M. Pezzuto

Researcher at Long Island University

Publications -  599
Citations -  38474

John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.

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Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2.

TL;DR: The EtOAc-soluble extract of the stems of M. pomiferus was found to inhibit the enzyme cyclooxygenase-2 (COX-2) and led to the isolation of two dibenzylbutyrolactone lignans and seven known compounds.
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NF-κB Inhibitory and Antibacterial Helvolic and Fumagillin Derivatives from Aspergillus terreus.

TL;DR: Two new helvolic acid analogues and one new fumagillin derivative containing an octahydroisobenzofuran moiety, together with four known compounds, were isolated from an Aspergillus terreus, isolated from soil collected from Mauna Kea, the highest mountain in Hawaii.
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Irisones A and B: two new isoflavones from Iris missouriensis.

TL;DR: Two new isoflavones, irisones A and B, together with the known compound, 5,7-dihydroxy-2',6-dimethoxy is oflavone, were isolated from the roots of Iris missouriensis with the help of 2D-homonuclear-J-correlation and2D-nOe experiments.
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Resveratrol inhibits rhabdomyosarcoma cell proliferation.

TL;DR: It is shown that resveratrol exerts a strong inhibition of rhabdomyosarcoma cell proliferation in part by arresting cells in S/G2 phase of the cell cycle.