J
John M. Pezzuto
Researcher at Long Island University
Publications - 599
Citations - 38474
John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.
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Journal ArticleDOI
Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase
Han-Dong Sun,Sheng-Xiang Qiu,Long-Ze Lin,Zong-yu Wang,Zhong-wen Lin,Thitima Pengsuparp,John M. Pezzuto,Harry H. S. Fong,Geoffrey A. Cordell,Norman R. Farnsworth +9 more
TL;DR: Nigranoic acid showed activity in several anti-HIV reverse transcriptase and polymerase assays and its structure elucidation and unambiguous NMR spectral assignment were achieved by the combination of 1D- and 2D-NMR techniques with the aid of computer modeling.
PatentDOI
Aromatase inhibitors from Broussonetia papyrifera
TL;DR: In this article, a composition and method of cancer treatment using B. papyrifera extract and compounds having aromatase inhibition properties was presented. But the method was not described.
Journal ArticleDOI
Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways.
TL;DR: The results suggest that the effects of resveratrol on AP-1 and MAPK pathways may involve the inhibition of both protein tyrosine kinases and protein kinase C.
Journal ArticleDOI
Inhibition of aromatase activity by flavonoids.
TL;DR: In searching for potent cancer chemopreventive agents from synthetic or natural products, 28 randomly selected flavonoids were screened for inhibitory effects against partially purified aromatase prepared from human placenta, with greatest activity being demonstrated with apigenin,rysin, and hesperetin.
Journal ArticleDOI
Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits
Sarot Cheenpracha,Eun-Jung Park,Wesley Y. Yoshida,Chaz Barit,Marisa M. Wall,John M. Pezzuto,Leng Chee Chang +6 more
TL;DR: Bioassay-guided isolation and purification of the ethyl acetate extract of Moringa oleifera fruits yielded three new phenolic glycosides that are reported to have potent NO-inhibitory activity and reduced LPS-mediated iNOS expression.