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John M. Pezzuto

Researcher at Long Island University

Publications -  599
Citations -  38474

John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.

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A rapid and sensitive bioassay involving cultured rat glioma cells to screen for substances capable of elevating intracellular cyclic AMP concentration.

TL;DR: The astrocyte formation assay appears to provide several advantages that make it attractive as a screen for the detection or evaluation of substances capable of elevating intracellular cAMP concentration.
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Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosum

TL;DR: Two new azaphilones, chaetoviridins J and K, along with five known derivatives, were isolated from leaves of Wikstroemia uva-ursi and evaluated for their cancer chemopreventive-potential based on their abilities to inhibit tumor necrosis factor alpha-induced nuclear factor-kappa B (NF-κB).
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Herbicidin Congeners, Undecose Nucleosides from an Organic Extract of Streptomyces sp. L-9-10

TL;DR: Four new undecose nucleosides (herbicidin congeners), three known herbicidins, and 9-(β-d-arabinofuranosyl)hypoxanthine (Ara-H) were isolated from the organic extract of a fermentation culture of Streptomyces sp.
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Isolation of echinocystic acid-3-O-sulfate, a new triterpene, from Tetrapleura tetraptera, and evaluation of the mutagenic potential of molluscicidal extracts and isolates.

TL;DR: The stem bark isolates, which included aridanin, 3-O-(2'-acetamido-2'-deoxy-beta-D-glucopyranosyl)echinocystic acid, and compounds 3 and 4, were not mutagenic either with or without metabolic activation.