J
John M. Pezzuto
Researcher at Long Island University
Publications - 599
Citations - 38474
John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.
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Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei.
Kittisak Likhitwitayawuid,Cindy K. Angerhofer,Heebyung Chai,John M. Pezzuto,Geoffrey A. Cordell,Nijsiri Ruangrungsi +5 more
TL;DR: Comparison of the alkaloid content of S. pierrei and Stephania erecta strongly suggested separate identities for the two plants, and cytotoxic and antimalarial activity was found.
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Natural Product Polyphenols of Relevance to Human Health
TL;DR: Results are promising, but additional research on the molecular mechanism of action of polyphenols and their application to human health is required.
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Novel Marine Phenazines as Potential Cancer Chemopreventive and Anti-Inflammatory Agents
Tamara P. Kondratyuk,Eun-Jung Park,Rui Yu,Richard B. van Breemen,Ratnakar N. Asolkar,Brian T. Murphy,William Fenical,John M. Pezzuto +7 more
TL;DR: In mammalian cell culture studies, compounds 1, 2 and 3 inhibited TNF-α-induced NFκB activity and LPS-induced nitric oxide production and provided greater insight on the biological potential of phenazine derivatives, and some guidance on how various substituents may alter potential anti-inflammatory and anti-cancer effects.
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Cytotoxic biflavonoids from Selaginella willdenowii
Gloria L. Silva,Heebyung Chai,Mahabir P. Gupta,Norman R. Farnsworth,Geoffrey A. Cordell,John M. Pezzuto,Chris Beecher,A. Douglas Kinghorn +7 more
TL;DR: Bioactivity-guided fractionation of the leaves of Selaginella willdenowii afforded three known biflavones, 4',7"-di-O-methylamentoflavone, isocryptomerin and 7"-O-methylrobustaflavone that were significantly cytotoxic against a panel of human cancer cell lines.
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Activity-guided isolation of antioxidative constituents of Cotinus coggygria.
H. E. Westenburg,K. J. Lee,Sang Kook Lee,Harry H. S. Fong,RB van Breemen,John M. Pezzuto,A. D. Kinghorn +6 more
TL;DR: Six constituents of the novel biaurone 1 were isolated from EtOAc-soluble partitions of two separate collections of the whole plants of Cotinus coggygria and found to be potent antioxidants in a 1,1-diphenyl-2-picrylhydrazyl free-radical scavenging assay.