scispace - formally typeset
J

John M. Pezzuto

Researcher at Long Island University

Publications -  599
Citations -  38474

John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.

Papers
More filters
Journal ArticleDOI

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

Aimee L. Eggler, +4 more
- 19 Jul 2005 - 
TL;DR: A model is proposed that should aid in the understanding of Keap1-Nrf2 signaling mechanisms and is tested using a series of ARE inducers, suggesting that the direct disruption model for Keap 1-NRF2 is incorrect.
Journal ArticleDOI

Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive Agents.

Gordon M. Cragg, +1 more
- 01 Jan 2016 - 
TL;DR: Given the unfathomable diversity of nature, it is reasonable to suggest that chemical leads can be generated that are capable of interacting with most or possibly all therapeutic targets.
Journal ArticleDOI

Evaluation of Estrogenic Activity of Plant Extracts for the Potential Treatment of Menopausal Symptoms

Jianghua Liu, +11 more
- 24 Mar 2001 - 
TL;DR: Genistein was found to be the most effective of four red clover isoflavones tested in the above in vitro assays, suggesting a potential use for some dietary supplements, ingested by human beings, in the treatment of menopausal symptoms.
Journal ArticleDOI

Botanicals in Cancer Chemoprevention

Eun Jung Park, +1 more
- 01 Jan 2002 - 
TL;DR: Several lead compounds, such as brassinin (from cruciferous vegetables like Chinese cabbage), sulforaphane (from broccoli) and its analog sulforamate, withanolides (from tomatillos), and resveratrol (from grapes and peanuts) are in preclinical or clinical trials for cancer chemoprevention.
Journal ArticleDOI

Cancer prevention with natural compounds.

Norleena Gullett, +8 more
- 01 Jun 2010 - 
TL;DR: Potential natural cancer preventive compounds and their mechanisms of action are discussed.