J
John M. Pezzuto
Researcher at Long Island University
Publications - 599
Citations - 38474
John M. Pezzuto is an academic researcher from Long Island University. The author has contributed to research in topics: Cancer & Resveratrol. The author has an hindex of 88, co-authored 588 publications receiving 35901 citations. Previous affiliations of John M. Pezzuto include Purdue University & Bandung Institute of Technology.
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New Chemical Constituents of Euphorbia quinquecostata and Absolute Configuration Assignment by a Convenient Mosher Ester Procedure Carried Out in NMR Tubes
Bao Ning Su,Eun Jung Park,Zakaria H. Mbwambo,Bernard D. Santarsiero,Andrew D. Mesecar,Harry H. S. Fong,John M. Pezzuto,A. Douglas Kinghorn +7 more
TL;DR: Two new compounds, an ent-isopimarane-type diterpene, 3alpha,12alpha-dihydroxy-ent-8(14),15- isopimaradien-18-al (1), and a dihydrobenzo[b]furan neolignan, (-)-trans-9-acetyl-4,9'-di-O-methyl-3'-de-O
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Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (±)-calanolide A and its enantiomers
Michael T. Flavin,John D. Rizzo,Albert Khilevich,Alla Kucherenko,Abram Kivovich Sheinkman,Vilayphone Vilaychack,Lin Lin,Wei Chen,Eugenia Mata Greenwood,Thitima Pengsuparp,John M. Pezzuto,Stephen H. Hughes,Thomas M. Flavin,Michael Cibulski,William A. Boulanger,Robert L. Shone,Ze-Qi Xu +16 more
TL;DR: The anti-HIV agent (+/-)-calanolide A (1) has been synthesized in a five-step approach starting with phloroglucinol, which includes Pechmann reaction, Friedel-Crafts acylation, chromenylation with 4,4-dimethoxy- 2-methylbutan-2-ol, cyclization, and Luche reduction.
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Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile
Kittisak Likhitwitayawuid,Cindy K. Angerhofer,Heebyung Chai,John M. Pezzuto,Geoffrey A. Cordell,Nijsiri Ruangrungsi +5 more
TL;DR: A new alkaloid (-)-amabiline was isolated from the bulbs of Crinum amabile (Amaryllidaceae), and alkaloids 2, 4, and 5 were found to be the principal cytotoxic and antimalarial constituents.
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Grapes and human health: a perspective.
TL;DR: It is suggested that some of the copious amounts of data obtained with resveratrol may be relevant to grape consumption, especially responses that can be mediated by low concentrations of the substance.
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Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris.
Bang Yeon Hwang,Bao Ning Su,Heebyung Chai,Qiuwen Mi,Leonardus B.S. Kardono,Johar J. Afriastini,Soedarsono Riswan,Bernard D. Santarsiero,Andrew D. Mesecar,Robert A. Wild,Craig R. Fairchild,Gregory D. Vite,William C. Rose,Norman R. Farnsworth,Geoffrey A. Cordell,John M. Pezzuto,Steven M. Swanson,A. Douglas Kinghorn +17 more
TL;DR: Two cytotoxic rocaglate derivatives possessing an unusual dioxanyloxy unit, silvestrol and episilvestrol, were isolated from the fruits and twigs of Aglaia silvestris by bioassay-guided fractionation monitored with a human oral epidermoid carcinoma (KB) cell line.