Josef Frank

TL;DR: This is the first report of an association between a BD risk gene and BPD where selection was not based on a priori hypotheses about its function, but on an unbiased hypothesis-free screening of the genome.

TL;DR: This report of lower methylation levels in NR3C1 in Externalizing disorders may indicate a mechanism through which the differential development of externalizing disorders as opposed to depressive disorders might occur.

TL;DR: Repl replication results from 22 independent schizophrenia case-control datasets from the Psychiatric Genomics Consortium are described, unable to replicate the significant association between ROH burden and schizophrenia in the independent PGC phase II data, although the effect was in the predicted direction.

TL;DR: The present findings suggest that STAB1 is a new and highly promising candidate gene in this region, and the combining of gene expression and GWAS data may provide valuable insights into the biological mechanisms of BD.

TL;DR: In this paper, the authors tested whether genetic variation in the major histocompatibility complex (MHC), which is associated with risk for autoimmune diseases, is also associated with the risk for depression.