J
Juan Carlos de la Torre
Researcher at Scripps Research Institute
Publications - 223
Citations - 13046
Juan Carlos de la Torre is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Arenavirus & Virus. The author has an hindex of 61, co-authored 209 publications receiving 10918 citations. Previous affiliations of Juan Carlos de la Torre include Université Paris-Saclay & Spanish National Research Council.
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Journal ArticleDOI
Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling
John R. Teijaro,Cherie T. Ng,Andrew M. Lee,Brian M. Sullivan,Kathleen C. F. Sheehan,Megan J. Welch,Robert D. Schreiber,Juan Carlos de la Torre,Michael B. A. Oldstone +8 more
TL;DR: A direct causal link between IFN-I signaling, immune activation, negative immune regulator expression, lymphoid tissue disorganization, and virus persistence is demonstrated and the results suggest that therapies targeting IFn-I may help control persistent virus infections.
Journal ArticleDOI
Variability in the analysis of a single neuroimaging dataset by many teams
Rotem Botvinik-Nezer,Rotem Botvinik-Nezer,Felix Holzmeister,Colin F. Camerer,Anna Dreber,Anna Dreber,Juergen Huber,Magnus Johannesson,Michael Kirchler,Roni Iwanir,Jeanette A. Mumford,R. Alison Adcock,Paolo Avesani,Paolo Avesani,Blazej M. Baczkowski,Aahana Bajracharya,Leah Bakst,Sheryl B. Ball,Marco Barilari,Nadège Bault,Derek Beaton,Julia Beitner,Julia Beitner,Roland G. Benoit,Ruud Berkers,Jamil P. Bhanji,Bharat B. Biswal,Bharat B. Biswal,Sebastian Bobadilla-Suarez,Tiago Bortolini,Katherine L. Bottenhorn,Alexander Bowring,Senne Braem,Senne Braem,Hayley R. Brooks,Emily G. Brudner,Cristian Buc Calderon,Julia A. Camilleri,Jaime J. Castrellon,Luca Cecchetti,Edna C. Cieslik,Zachary J. Cole,Olivier Collignon,Olivier Collignon,Robert W. Cox,William A. Cunningham,Stefan Czoschke,Kamalaker Dadi,Charles P. Davis,Alberto De Luca,Mauricio R. Delgado,Lysia Demetriou,Lysia Demetriou,Jeffrey B. Dennison,Xin Di,Xin Di,Erin W. Dickie,Ekaterina Dobryakova,Claire Donnat,Juergen Dukart,Niall W. Duncan,Joke Durnez,Amr Eed,Simon B. Eickhoff,Andrew Erhart,Laura Fontanesi,G. Matthew Fricke,Fu Shiguang,Adriana Galván,Remi Gau,Sarah Genon,Tristan Glatard,Enrico Glerean,Jelle J. Goeman,Sergej A.E. Golowin,Carlos González-García,Krzysztof J. Gorgolewski,Cheryl L. Grady,Mikella A. Green,João F. Guassi Moreira,Olivia Guest,Shabnam Hakimi,J. Paul Hamilton,Roeland Hancock,Giacomo Handjaras,Bronson Harry,Colin Hawco,Peer Herholz,Gabrielle Herman,Stephan Heunis,Felix Hoffstaedter,Jeremy Hogeveen,Susan Holmes,Chuan-Peng Hu,Scott A. Huettel,Matthew Hughes,Vittorio Iacovella,Alexandru D. Iordan,Peder M. Isager,Ayse Ilkay Isik,Andrew Jahn,Matthew R. Johnson,Tom Johnstone,Michael Joseph,Anthony C. Juliano,Joseph W. Kable,Michalis Kassinopoulos,Cemal Koba,Xiangzhen Kong,Timothy R. Koscik,Nuri Erkut Kucukboyaci,Nuri Erkut Kucukboyaci,Brice A. Kuhl,Sebastian Kupek,Angela R. Laird,Claus Lamm,Robert Langner,Nina Lauharatanahirun,Hongmi Lee,Sangil Lee,Alexander Leemans,Andrea Leo,Elise Lesage,Flora Li,Monica Y.C. Li,Monica Y.C. Li,Phui Cheng Lim,Evan N. Lintz,Schuyler W. Liphardt,Annabel B. Losecaat Vermeer,Bradley C. Love,Bradley C. Love,Michael Mack,Norberto Malpica,Theo Marins,Camille Maumet,Kelsey McDonald,Joseph T. McGuire,Helena Melero,Helena Melero,Adriana S. Méndez Leal,Benjamin Meyer,Benjamin Meyer,Kristin N. Meyer,Glad Mihai,Glad Mihai,Georgios D. Mitsis,Jorge Moll,Dylan M. Nielson,Gustav Nilsonne,Gustav Nilsonne,Michael Notter,Emanuele Olivetti,Emanuele Olivetti,Adrian I. Onicas,Paolo Papale,Paolo Papale,Kaustubh R. Patil,Jonathan E. Peelle,Alexandre Pérez,Doris Pischedda,Jean-Baptiste Poline,Jean-Baptiste Poline,Yanina Prystauka,Shruti Ray,Patricia A. Reuter-Lorenz,Richard C. Reynolds,Emiliano Ricciardi,Jenny R. Rieck,Anais Rodriguez-Thompson,Anthony Romyn,Taylor Salo,Gregory R. Samanez-Larkin,Emilio Sanz-Morales,Margaret L. Schlichting,Douglas H. Schultz,Qiang Shen,Margaret A. Sheridan,Jennifer A. Silvers,Kenny Skagerlund,Alec Smith,David V. Smith,Peter Sokol-Hessner,Simon R. Steinkamp,Sarah M. Tashjian,Bertrand Thirion,John Thorp,Gustav Tinghög,Loreen Tisdall,Loreen Tisdall,Steven H. Tompson,Claudio Toro-Serey,Juan Carlos de la Torre,Leonardo Tozzi,Vuong Truong,Luca Turella,Anna van 't Veer,Tom Verguts,Jean M. Vettel,Jean M. Vettel,Jean M. Vettel,Sagana Vijayarajah,Khoi Vo,Matthew B. Wall,Matthew B. Wall,Wouter D. Weeda,Susanne Weis,David J. White,David Wisniewski,Alba Xifra-Porxas,Emily A. Yearling,Sangsuk Yoon,Rui Yuan,Kenneth S. L. Yuen,Kenneth S. L. Yuen,Lei Zhang,Xu Zhang,Joshua E. Zosky,Thomas E. Nichols,Russell A. Poldrack,Tom Schonberg +220 more
TL;DR: The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
Journal ArticleDOI
The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance — a review
Esteban Domingo,Encarnación Martínez-Salas,Francisco Sobrino,Juan Carlos de la Torre,Agustín Portela,Juan Ortín,Cecilio López-Galíndez,Pilar Pérez-Breña,Nieves Villanueva,Rafael Nájera,Scott VandePol,David A. Steinhauer,Nicholas J. Depolo,John J. Holland +13 more
TL;DR: Evidence that cloned (or uncloned) populations of most RNA viruses do not consist of a single genome species of defined sequence, but rather of heterogeneous mixtures of related genomes (quasispecies) is reviewed.
Journal ArticleDOI
The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis
Carmen Gerlach,E. Ashley Moseman,Scott Loughhead,David Alvarez,Anthonie J. Zwijnenburg,Lisette Waanders,Rohit Garg,Juan Carlos de la Torre,Ulrich H. von Andrian,Ulrich H. von Andrian +9 more
TL;DR: A subset of CX3CR1int Tmem cells present unique phenotypic, homeostatic, and migratory properties, and it is proposed that tpm cells are chiefly responsible for the global surveillance of non-lymphoid tissues.
Journal ArticleDOI
The small RING finger protein Z drives arenavirus budding: Implications for antiviral strategies
TL;DR: Results indicate that Z is the arenavirus functional counterpart of the matrix proteins found in other negative strand enveloped RNA viruses, and members of the vacuolar protein sorting pathway appear to play an important role in arena-virus budding.