J
Jürg Bähler
Researcher at University College London
Publications - 237
Citations - 24955
Jürg Bähler is an academic researcher from University College London. The author has contributed to research in topics: Schizosaccharomyces pombe & Gene. The author has an hindex of 67, co-authored 227 publications receiving 21327 citations. Previous affiliations of Jürg Bähler include University of Debrecen & European Bioinformatics Institute.
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Journal ArticleDOI
Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe
Jürg Bähler,Jian-Qiu Wu,Mark S. Longtine,Nirav Shah,Amos Mckenzie,Alexander B. Steever,Achim Wach,Peter Philippsen,John R. Pringle +8 more
TL;DR: A straightforward PCR‐based approach to the deletion, tagging, and overexpression of genes in their normal chromosomal locations in the fission yeast Schizosaccharomyces pombe, and a series of plasmids containing the kanMX6 module, which allows selection of G418‐resistant cells and thus provides a new heterologous marker for use in S. pom be.
Journal ArticleDOI
The Gene Ontology Resource: 20 years and still GOing strong
Seth Carbon,Eric Douglass,Nathan Dunn,Benjamin M. Good,Nomi L. Harris,Suzanna E. Lewis,Christopher J. Mungall,S. Basu,Rex L. Chisholm,Robert J. Dodson,E. Hartline,Petra Fey,Paul Thomas,Laurent-Philippe Albou,Dustin Ebert,M. J. Kesling,Huaiyu Mi,Anushya Muruganujan,Xiaosong Huang,S. Poudel,Tremayne Mushayahama,James C. Hu,Sandra A. LaBonte,Deborah A. Siegele,Giulia Antonazzo,Helen Attrill,Nicholas H. Brown,S. Fexova,Phani V. Garapati,T. E.M. Jones,Steven J Marygold,Gillian Millburn,Alix J. Rey,Vítor Trovisco,G. Dos Santos,David B. Emmert,Kathleen Falls,Pinglei Zhou,Joshua L. Goodman,Victor B. Strelets,Jim Thurmond,Mélanie Courtot,D. S. Osumi,Helen Parkinson,Paola Roncaglia,Marcio Luis Acencio,Martin Kuiper,A. Lreid,Colin Logie,Ruth C. Lovering,Rachael P. Huntley,Paul Denny,Nancy H. Campbell,Barbara Kramarz,Vanessa Acquaah,S. H. Ahmad,H. Chen,J. H. Rawson,Marcus C. Chibucos,Michelle G. Giglio,Suvarna Nadendla,Rebecca Tauber,Margaret Duesbury,N. T. Del,Birgit H M Meldal,Livia Perfetto,Pablo Porras,Sandra Orchard,Anjali Shrivastava,Z. Xie,Hsin-Yu Chang,Robert D. Finn,Alex L. Mitchell,Neil D. Rawlings,Lorna Richardson,Amaia Sangrador-Vegas,Judith A. Blake,Karen R. Christie,Mary E. Dolan,H. Drabkin,David P. Hill,Li Ni,D. Sitnikov,Midori A. Harris,Stephen G. Oliver,Kim Rutherford,Valerie Wood,Jacqueline Hayles,Jürg Bähler,Antonia Lock,Elizabeth R Bolton,J L De Pons,Melinda R. Dwinell,G. T. Hayman,Stan Laulederkind,Mary Shimoyama,Marek Tutaj,Shur-Jen Wang,Peter D'Eustachio,Lisa Matthews,James P. Balhoff,Suzi Aleksander,Gail Binkley,B. L. Dunn,J. M. Cherry,Stacia R. Engel,Felix Gondwe,Kalpana Karra,Kevin A. MacPherson,Stuart R. Miyasato,Robert S. Nash,P. C. Ng,Travis K. Sheppard,A. Shrivatsav Vp,Matt Simison,Marek S. Skrzypek,Shuai Weng,Edith D. Wong,Marc Feuermann,Pascale Gaudet,E. Bakker,Tanya Z. Berardini,Leonore Reiser,Shankar Subramaniam,Eva Huala,C. Arighi,A. Auchincloss,K. Axelsen,G. P. Argoud,Alex Bateman,B. Bely,M. C. Blatter,E. Boutet,L. Breuza,A. Bridge,R. Britto,H. Bye-A-Jee,C. Casals-Casas,E. Coudert,A. Estreicher,L. Famiglietti,P. Garmiri,George Georghiou,A. Gos,N. Gruaz-Gumowski,E. Hatton-Ellis,U. Hinz,C. Hulo,A. Ignatchenko,F. Jungo,G. Keller,K. Laiho,P. Lemercier,D. Lieberherr,Y. Lussi,A. Mac-Dougall,M. Magrane,Maria Jesus Martin,P. Masson,D. A. Natale,N. N. Hyka,I. Pedruzzi,K. Pichler,S. Poux,C. Rivoire,M. Rodriguez-Lopez,T. Sawford,Elena Speretta,A. Shypitsyna,A. Stutz,S. Sundaram,M. Tognolli,N. Tyagi,Kate Warner,Rossana Zaru,C. Wu,Juancarlos Chan,J. Cho,Sibyl Gao,Christian A. Grove,M. C. Harrison,Kevin L. Howe,Raymond Lee,Jane E. Mendel,Hans-Michael Müller,Daniela Raciti,K. Van Auken,Matthew Berriman,Lincoln Stein,Paul W. Sternberg,Doug Howe,Sabrina Toro,Monte Westerfield +192 more
TL;DR: GO-CAM, a new framework for representing gene function that is more expressive than standard GO annotations, has been released, and users can now explore the growing repository of these models.
Journal ArticleDOI
The Gene Ontology resource: enriching a GOld mine
Seth Carbon,Eric Douglass,Benjamin M. Good,Deepak Unni,Nomi L. Harris,Christopher J. Mungall,Siddartha Basu,Rex L. Chisholm,Robert J. Dodson,Eric Hartline,Petra Fey,Paul Thomas,Laurent-Philippe Albou,Dustin Ebert,Michael J Kesling,Huaiyu Mi,Anushya Muruganujan,Xiaosong Huang,Tremayne Mushayahama,Sandra A. LaBonte,Deborah A. Siegele,Giulia Antonazzo,Helen Attrill,Nicholas H. Brown,Phani V. Garapati,Steven J Marygold,Vítor Trovisco,Gil dos Santos,Kathleen Falls,Christopher J. Tabone,Pinglei Zhou,Joshua L. Goodman,Victor B. Strelets,Jim Thurmond,Penelope Garmiri,Rizwan Ishtiaq,Milagros Rodríguez-López,Marcio Luis Acencio,Martin Kuiper,Astrid Lægreid,Colin Logie,Ruth C. Lovering,Barbara Kramarz,Shirin C C Saverimuttu,Sandra M Pinheiro,Heather Gunn,Renzhi Su,Katherine E Thurlow,Marcus C. Chibucos,Michelle G. Giglio,Suvarna Nadendla,James B. Munro,Rebecca C. Jackson,Margaret Duesbury,Noemi del-Toro,Birgit H M Meldal,Kalpana Paneerselvam,Livia Perfetto,Pablo Porras,Sandra Orchard,Anjali Shrivastava,Hsin-Yu Chang,Robert D. Finn,Alex L. Mitchell,Neil D. Rawlings,Lorna Richardson,Amaia Sangrador-Vegas,Judith A. Blake,Karen R. Christie,Mary E. Dolan,Harold J. Drabkin,David P. Hill,Li Ni,D. Sitnikov,Midori A. Harris,Stephen G. Oliver,Kim Rutherford,Valerie Wood,Jaqueline Hayles,Jürg Bähler,Elizabeth R Bolton,Jeffery L De Pons,Melinda R. Dwinell,G. Thomas Hayman,Mary L. Kaldunski,Anne E. Kwitek,Stanley J. F. Laulederkind,Cody Plasterer,Marek Tutaj,Mahima Vedi,Shur-Jen Wang,Peter D'Eustachio,Lisa Matthews,James P. Balhoff,Suzi Aleksander,Michael J Alexander,J. Michael Cherry,Stacia R. Engel,Felix Gondwe,Kalpana Karra,Stuart R. Miyasato,Robert S. Nash,Matt Simison,Marek S. Skrzypek,Shuai Weng,Edith D. Wong,Marc Feuermann,Pascale Gaudet,Anne Morgat,Erica Bakker,Tanya Z. Berardini,Leonore Reiser,Shabari Subramaniam,Eva Huala,Cecilia N. Arighi,Andrea H. Auchincloss,Kristian B. Axelsen,Ghislaine Argoud-Puy,Alex Bateman,Marie-Claude Blatter,Emmanuel Boutet,Emily H. Bowler,Lionel Breuza,Alan Bridge,Ramona Britto,Hema Bye-A-Jee,Cristina Casals Casas,Elisabeth Coudert,Paul Denny,Anne Estreicher,Maria Livia Famiglietti,George Georghiou,Arnaud Gos,Nadine Gruaz-Gumowski,Emma Hatton-Ellis,Chantal Hulo,Alexandr Ignatchenko,Florence Jungo,Kati Laiho,Philippe Le Mercier,Damien Lieberherr,Antonia Lock,Yvonne Lussi,Alistair MacDougall,Michele Magrane,Maria Jesus Martin,Patrick Masson,Darren A. Natale,Nevila Hyka-Nouspikel,Ivo Pedruzzi,Lucille Pourcel,Sylvain Poux,Sangya Pundir,Catherine Rivoire,Elena Speretta,Shyamala Sundaram,Nidhi Tyagi,Kate Warner,Rossana Zaru,Cathy H. Wu,Alexander D. Diehl,Juancarlos Chan,Christian A. Grove,Raymond Lee,Hans-Michael Müller,Daniela Raciti,Kimberly Van Auken,Paul W. Sternberg,Matthew Berriman,Michael Paulini,Kevin L. Howe,Sibyl Gao,Adam Wright,Lincoln Stein,Douglas G. Howe,Sabrina Toro,Monte Westerfield,Pankaj Jaiswal,Laurel Cooper,Justin Elser +179 more
TL;DR: A historical archive covering the past 15 years of GO data with a consistent format and file structure for both the ontology and annotations is made available to maintain consistency with other ontologies.
Journal ArticleDOI
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution
Brian T. Wilhelm,Brian T. Wilhelm,Samuel Marguerat,Samuel Marguerat,Stephen Watt,Stephen Watt,Falk Schubert,Falk Schubert,Valerie Wood,Ian Goodhead,Ian Goodhead,Christopher J. Penkett,Christopher J. Penkett,Jane Rogers,Jürg Bähler,Jürg Bähler +15 more
TL;DR: High-throughput sequencing of complementary DNAs (RNA-Seq) and strand-specific array data provide rich condition-specific information on novel, mostly non-coding transcripts, untranslated regions and gene structures, thus improving the existing genome annotation.
Journal ArticleDOI
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation.
TL;DR: A range of recent studies give fascinating insight into cellular strategies for keeping gene expression in tune with physiological needs dictated by the environment, promoting adaptation to both short- and long-term environmental changes.