S
Steve Gallinger
Researcher at University of Toronto
Publications - 105
Citations - 9600
Steve Gallinger is an academic researcher from University of Toronto. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 44, co-authored 105 publications receiving 8875 citations. Previous affiliations of Steve Gallinger include Icahn School of Medicine at Mount Sinai & University Health Network.
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International network of cancer genome projects
Thomas J. Hudson,Thomas J. Hudson,Warwick Anderson,Axel Aretz,Anna D. Barker,Cindy Bell,Rosa R. Bernabé,Maharaj K. Bhan,Fabien Calvo,Iiro Eerola,Daniela S. Gerhard,Alan E. Guttmacher,Mark S. Guyer,Fiona M. Hemsley,Jennifer L. Jennings,David J. Kerr,Peter Klatt,Patrik Kolar,Jun Kusuda,David P. Lane,Frank Laplace,Youyong Lu,Gerd Nettekoven,Brad Ozenberger,Jane Peterson,T. S. Rao,Jacques Remacle,Alan J. Schafer,Tatsuhiro Shibata,Michael R. Stratton,Joseph G. Vockley,Koichi Watanabe,Huanming Yang,Matthew Ming Fai Yuen,Bartha Maria Knoppers,Martin Bobrow,Anne Cambon-Thomsen,Lynn G. Dressler,Stephanie O.M. Dyke,Yann Joly,Kazuto Kato,Karen Kennedy,Pilar Nicolás,Michael Parker,Emmanuelle Rial-Sebbag,Carlos M. Romeo-Casabona,Kenna M. Shaw,Susan E. Wallace,Georgia L. Wiesner,Nikolajs Zeps,Peter Lichter,Andrew V. Biankin,Andrew V. Biankin,Christian Chabannon,Lynda Chin,Bruno Clément,Enrique de Alava,Françoise Degos,Martin L. Ferguson,Peter Geary,D. Neil Hayes,Amber L. Johns,Arek Kasprzyk,Hidewaki Nakagawa,Robert Penny,Miguel A. Piris,Rajiv Sarin,Aldo Scarpa,Marc J. van de Vijver,Marc J. van de Vijver,P. Andrew Futreal,Hiroyuki Aburatani,Mònica Bayés,David D.L. Bowtell,David D.L. Bowtell,Peter J. Campbel,Peter J. Campbel,Xavier Estivill,Sean M. Grimmond,Ivo Gut,Martin Hirst,Carlos López-Otý́n,Partha P. Majumder,Marco A. Marra,John Douglas Mcpherson,John Douglas Mcpherson,Zemin Ning,Xose S. Puente,Yijun Ruan,Hendrik G. Stunnenberg,Harold Swerdlow,Victor E. Velculescu,Richard K. Wilson,Hong Xue,Liu Yang,Paul T. Spellman,Gary D. Bader,Paul C. Boutros,Paul Flicek,Gad Getz,Roderic Guigó,Guangwu Guo,David Haussler,Simon Heath,Tim Hubbard,Tao Jiang,Steven J. M. Jones,Qibin Li,Nuria Lopez-Bigas,Ruibang Luo,Lakshmi Muthuswamy,B. F. Francis Ouellette,John V. Pearson,Víctor Quesada,Benjamin J. Raphael,Chris Sander,Terence P. Speed,Terence P. Speed,Lincoln Stein,Joshua M. Stuart,Jon W. Teague,Yasushi Totoki,Tatsuhiko Tsunoda,Alfonso Valencia,David A. Wheeler,Honglong Wu,Shancen Zhao,Guangyu Zhou,Mark Lathrop,Gilles Thomas,Teruhiko Yoshida,Myles Axton,Chris Gunter,Linda Miller,Junjun Zhang,Syed Haider,Jianxin Wang,Christina K. Yung,Anthony Cross,Yong Liang,Saravanamuttu Gnaneshan,Jonathan M. Guberman,Jack Hsu,Don Chalmers,Karl W. Hasel,Terry Sheung-Hung Kaan,William W. Lowrance,Tohru Masui,Laura Lyman Rodriguez,Catherine Vergely,David D.L. Bowtel,Nicole Cloonan,Anna deFazio,Anna deFazio,James R. Eshleman,Dariush Etemadmoghadam,Dariush Etemadmoghadam,Brooke A. Gardiner,James G. Kench,James G. Kench,Robert L. Sutherland,Margaret A. Tempero,Nicola Waddell,Peter Wilson,Steve Gallinger,Steve Gallinger,Ming-Sound Tsao,Ming-Sound Tsao,Patricia Shaw,Gloria M. Petersen,Debabrata Mukhopadhyay,Ronald A. DePinho,Sarah P. Thayer,Kamran Shazand,Timothy Beck,Michelle Sam,Lee Timms,Vanessa Ballin,Jiafu Ji,Xiuqing Zhang,Feng Chen,Xueda Hu,Qi Yang,Geng Tian,Lianhai Zhang,Xiaofang Xing,Xianghong Li,Zhenggang Zhu,Yingyan Yu,Jun Yu,Jörg Tost,Paul Brennan,Ivana Holcatova,David Zaridze,Alvis Brazma,Lars Egevad,Egor Prokhortchouk,Rosamonde E. Banks,Mathias Uhlén,Juris Viksna,Fredrik Pontén,Konstantin G. Skryabin,P. Andrew Futrea,Ewan Birney,Åke Borg,Anne Lise Børresen-Dale,Carlos Caldas,John A. Foekens,Sancha Martin,Jorge S. Reis-Filho,Andrea L. Richardson,Christos Sotiriou,Laura van 't Veer,Daniel Birnbaum,Hélène Blanché,Pascal Boucher,Sandrine Boyault,Jocelyne D. Masson-Jacquemier,Iris Pauporté,Xavier Pivot,Anne Vincent-Salomon,Eric Tabone,Charles Theillet,Isabelle Treilleux,Paulette Bioulac-Sage,Thomas Decaens,Franc OiseDegos,Dominique Franco,Gut M,Didier Samuel,Jessica Zucman-Rossi,Roland Eils,Roland Eils,Benedikt Brors,Jan O. Korbe,Andrey Korshunov,Pablo Landgraf,Hans Lehrach,Stefan M. Pfister,Stefan M. Pfister,Bernhard Radlwimmer,Guido Reifenberger,Michael D. Taylor,Christof von Kalle,Partha P. Majumder,Paolo Pederzoli,Rita T. Lawlor,Massimo Delledonne,Alberto Bardelli,Thomas M. Gress,David S. Klimstra,Giuseppe Zamboni,Yusuke Nakamura,Satoru Miyano,Akihiro Fujimoto,Elias Campo,Silvia de Sanjosé,Emili Montserrat,Marcos González-Dý́az,Pedro Jares,Heinz Himmelbaue,Sílvia Beà,Samuel Aparicio,Douglas F. Easton,Francis S. Collins,Carolyn C. Compton,Eric S. Lander,Wylie Burke,Anthony R. Green,Stanley R. Hamilton,Olli Kallioniemi,Timothy J. Ley,Edison T. Liu,Brandon J. Wainwright +273 more
TL;DR: Systematic studies of more than 25,000 cancer genomes will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.
Journal ArticleDOI
Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors
Noralane M. Lindor,Lawrence J. Burgart,Olga Leontovich,Richard M. Goldberg,Julie M. Cunningham,Daniel J. Sargent,Catherine Walsh-Vockley,Gloria M. Petersen,Michael Walsh,Barbara A. Leggett,Joanne P. Young,Melissa A. Barker,Jeremy R. Jass,John L. Hopper,Steve Gallinger,Bharati Bapat,Mark Redston,Stephen N. Thibodeau +17 more
TL;DR: IHC in colorectal tumors for protein products hMLH1 and hMSH2 provides a rapid, cost-effective, sensitive, and extremely specific method for screening for DNA mismatch repair defects.
Journal ArticleDOI
Lower Cancer Incidence in Amsterdam-I Criteria Families Without Mismatch Repair Deficiency: Familial Colorectal Cancer Type X
Noralane M. Lindor,Kari G. Rabe,Gloria M. Petersen,Robert W. Haile,Graham Casey,John A. Baron,Steve Gallinger,Bharati Bapat,Melyssa Aronson,John L. Hopper,Jeremy R. Jass,Loic LeMarchand,John S. Grove,John D. Potter,Polly A. Newcomb,Jonathan P. Terdiman,Peggy Conrad,Gabriella Moslein,Richard M. Goldberg,Argyrios Ziogas,Hoda Anton-Culver,Mariza de Andrade,Kim Siegmund,Stephen N. Thibodeau,Lisa A. Boardman,Daniela Seminara +25 more
TL;DR: Families who fulfill AC-I criteria but who have no evidence of a DNA MMR defect do not share the same cancer incidence as families with HNPCC-Lynch syndrome, and the designation of "familial colorectal cancer type X" is suggested to describe this type of familial aggregation of coloreCTal cancer.
Journal ArticleDOI
MSH2 deficient mice are viable and susceptible to lymphoid tumours.
Armin Reitmair,Rudolf Schmits,A. Ewel,Bharati Bapat,Mark Redston,Angela Mitri,Paul Waterhouse,Hans-Willi Mittrücker,Andrew Wakeham,B. Liu,A. Thomason,Henrik Griesser,Steve Gallinger,W.G. Ballhausen,Richard Fishel,T. W. Mak +15 more
TL;DR: A direct link between MSH2 deficiency and the pathogenesis of cancer is established and these mutant mice should be good models to study the progression of tumours and also to screen carcinogenic and anti–cancer agents.
Journal ArticleDOI
Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria
Angela Brooks-Wilson,Pardeep Kaurah,G Suriano,Stephen Leach,Janine Senz,Nicola Grehan,Yaron S.N. Butterfield,J Jeyes,J Schinas,J Bacani,Megan M. Kelsey,Paulo Ademar Avelar Ferreira,B MacGillivray,Patrick MacLeod,M Micek,James M. Ford,William D. Foulkes,Karlene Australie,Cheryl R. Greenberg,M LaPointe,Cathy Gilpin,Sarah M. Nikkel,Dawna Gilchrist,R Hughes,Charles E. Jackson,Kristin G. Monaghan,Maria José Oliveira,Raquel Seruca,Steve Gallinger,Carlos Caldas,David G. Huntsman +30 more
TL;DR: Germline truncating CDH1 mutations are found in 48% of families with multiple cases of gastric cancer and at least one documented case of DGC in an individual under 50 years of age, and this work recommends that these criteria be used for selecting families forCDH1 mutational analysis.