M
Mark A. Mintun
Researcher at Washington University in St. Louis
Publications - 246
Citations - 50518
Mark A. Mintun is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Positron emission tomography & Alzheimer's disease. The author has an hindex of 91, co-authored 230 publications receiving 47308 citations. Previous affiliations of Mark A. Mintun include University of Kansas & University of Pittsburgh.
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Journal ArticleDOI
Positron emission tomographic imaging of serotonin activation effects on prefrontal cortex in healthy volunteers.
TL;DR: The positron emission tomography 18F-fluorodeoxyglucose (18FDG) method is used to examine the fenfluramine-induced changes in regional cerebral glucose metabolism (rCMRglu) to study abnormalities of serotonin function in the prefrontal cortex.
Journal ArticleDOI
Type 2 diabetes mellitus, brain atrophy, and cognitive decline
Chris Moran,Richard Beare,Wei Wang,Michele L. Callisaya,Velandai Srikanth,Velandai Srikanth,Michael W. Weiner,Paul S. Aisen,Ronald C. Petersen,Clifford R. Jack,William J. Jagust,John Q. Trojanowki,Arthur W. Toga,Laurel A. Beckett,Robert C. Green,Andrew J. Saykin,John C. Morris,Enchi Liu,T. J. Montine,Anthony Gamst,Ronald G. Thomas,Michael C. Donohue,Sarah Walter,Devon Gessert,Tamie Sather,Danielle J Harvey,John Kornak,Anders M. Dale,Matt A. Bernstein,Joel P. Felmlee,Nick C. Fox,Paul M. Thompson,Norbert Schuff,Gene E. Alexander,Charles DeCarli,Dan Bandy,Robert A. Koeppe,Norm Foster,Eric M. Reiman,Kewei Chen,Chet Mathis,Nigel J. Cairns,Lisa Taylor-Reinwald,J. Q. Trojanowki,Les Shaw,Virginia M.-Y. Lee,Magdalena Korecka,Karen Crawford,Scott C. Neu,Tatiana Foroud,Steven Potkin,Li Shen,Zaven Kachaturian,Richard Frank,Peter J. Snyder,Susan E. Molchan,Jeffrey Kaye,Joseph F. Quinn,Betty Lind,Sara Dolen,Lon S. Schneider,Sonia Pawluczyk,Bryan M. Spann,James B. Brewer,Helen Vanderswag,Judith L. Heidebrink,Joanne L. Lord,Kris A. Johnson,Rachelle S. Doody,Javier Villanueva-Meyer,Munir Chowdhury,Yaakov Stern,Lawrence S. Honig,Karen L. Bell,Beau M. Ances,Maria Carroll,Sue Leon,Mark A. Mintun,Stacy Schneider,Daniel C. Marson,Randall Griffith,David J. Clark,Hillel Grossman,Effie M. Mitsis,Aliza Romirowsky,Leyla deToledo-Morrell,Raj C. Shah,Ranjan Duara,Daniel Varon,Peggy Roberts,Marilyn S. Albert,Chiadi U. Onyike,Stephanie Kielb,Henry Rusinek,Mony J. de Leon,Lidia Glodzik,Susan De Santi,P. Murali Doraiswamy,Jeffrey R. Petrella,R. Edward Coleman,Steven E. Arnold,Jason Karlawish,David A. Wolk,Charles D. Smith,Greg Jicha,Peter A. Hardy,Oscar L. Lopez,MaryAnn Oakley,Donna M. Simpson,Anton P. Porsteinsson,Bonnie S. Goldstein,Kim Martin,Kelly M. Makino,M. Saleem Ismail,Connie Brand,Ruth A. Mulnard,Gaby Thai,Catherine Mc-Adams-Ortiz,Kyle B. Womack,Dana Mathews,Mary Quiceno,Ramon Diaz-Arrastia,Richard D. King,Myron F. Weiner,Kristen Martin-Cook,Michael D. Devous,Allan I. Levey,James J. Lah,Janet S. Cellar,Jeffrey M. Burns,Heather Anderson,Russell H. Swerdlow,Liana G. Apostolova,Po H. Lu,George Bartzokis,Daniel H.S. Silverman,Neill R. Graff-Radford,Francine Parfitt,Heather E. Johnson,Martin R. Farlow,Ann Marie Hake,Brandy R. Matthews,Scott Herring,Christopher H. van Dyck,Richard E. Carson,Martha G. MacAvoy,Howard Chertkow,Howard Bergman,Chris Hosein,Sandra E. Black,Bojana Stefanovic,Curtis B. Caldwell,Ging-Yuek Robin Hsiung,Howard Feldman,Benita Mudge,Michele Assaly,Andrew Kertesz,John A. Rogers,Dick Trost,Charles Bernick,Donna Munic,Diana R. Kerwin,M.-Marsel Mesulam,Kristina Lipowski,Chuang Kuo Wu,Nancy Collins Johnson,Carl H. Sadowsky,Walter Martinez,Teresa Villena,Raymond Scott Turner,Kathleen R. Johnson,Brigid Reynolds,Reisa A. Sperling,Keith A. Johnson,Gad A. Marshall,Meghan Frey,Jerome A. Yesavage,Joy L. Taylor,Barton Lane,Allyson C. Rosen,Jared R. Tinklenberg,Marwan N. Sabbagh,Christine Belden,Sandra W. Jacobson,Neil W. Kowall,Ronald J. Killiany,Andrew E. Budson,Alexander Norbash,Patricia Lynn Johnson,Thomas O. Obisesan,Saba Wolday,Salome K. Bwayo,Alan J. Lerner,Leon Hudson,Paula Ogrocki,Evan Fletcher,Owen Carmichael,John M Olichney,Smita Kittur,Michael Borrie,Rob Bartha,Sterling C. Johnson,Sanjay Asthana,Cynthia M. Carlsson,Steven G. Potkin,Adrian Preda,Dana Nguyen,Pierre N. Tariot,Adam S. Fleisher,Stephanie Reeder,Vernice Bates,Horacio Capote,Michelle Rainka,Douglas W. Scharre,Maria Kataki,Earl A. Zimmerman,Dzintra Celmins,Alice D. Brown,Godfrey D. Pearlson,Karen Blank,Karen S. Anderson,Robert B. Santulli,Eben S. Schwartz,Kaycee M. Sink,Jeff D. Williamson,Pradeep Garg,Franklin Watkins,Brian R. Ott,Henry W. Querfurth,Geoffrey Tremont,Stephen Salloway,Paul Malloy,Stephen Correia,Howard J. Rosen,Bruce L. Miller,Jacobo Mintzer,Crystal V. Flynn Longmire,Kenneth M. Spicer,Elizabether Finger,Irina Rachinsky,Dick J. Drost,Nunzio Pomara,Raymundo Hernando,Antero Sarrael,Susan K. Schultz,Laura L. Boles Ponto,Hyungsub Shim,Karen E. Smith,Norman R. Relkin,Gloria Chaing,Lisa Raudin,Amanda Smith,Kristin Fargher,Balebail Ashok Raj +253 more
TL;DR: In an older cohort with low cerebrovascular disease burden, T2DM contributes to cognitive decline via neurodegeneration in older people with normal cognition, mild cognitive impairment, and Alzheimer disease.
Journal ArticleDOI
Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states
Ines Mahjoub,Ines Mahjoub,Mohamed Ali Mahjoub,Islem Rekik,Michael W. Weiner,Paul S. Aisen,Ronald C. Petersen,Cliford Jack,William J. Jagust,John Q. Trojanowki,Arthur W. Toga,Laurel A. Beckett,Robert C. Green,Andrew J. Saykin,John C. Morris,Leslie Shaw,Jefrey Kaye,Joseph F. Quinn,Lisa C. Silbert,Betty Lind,Raina Carter,Sara Dolen,L. Schneider,Sonia Pawluczyk,Mauricio Beccera,Liberty Teodoro,Bryan M. Spann,James B. Brewer,Helen Vanderswag,Adam S. Fleisher,Judith L. Heidebrink,Joanne L. Lord,Sara S. Mason,Colleen S. Albers,David S. Knopman,Kris Johnson,Rachelle S. Doody,Javier Villanueva-Meyer,Munir Chowdhury,Susan Rountree,Mimi Dang,Yaakov Stern,Lawrence S. Honig,Karen L. Bell,Beau M. Ances,Maria Carroll,Mary L. Creech,Erin E. Franklin,Mark A. Mintun,Stacy Schneider,Angela Oliver,Daniel C. Marson,Randall Grifth,David G. Clark,David S. Geldmacher,John C. Brockington,Erik D. Roberson,Marissa Natelson Love,Hillel Grossman,Efe Mitsis,Raj C. Shah,Leyla deToledo-Morrell,Ranjan Duara,Daniel Varon,Maria T. Greig,Peggy Roberts,Marilyn S. Albert,Chiadi U. Onyike,Daniel D'Agostino,Stephanie Kielb,James E. Galvin,Brittany Cerbone,Christina A. Michel,Dana M. Pogorelec,Henry Rusinek,Mony J. de Leon,Lidia Glodzik,Susan De Santi,P. M. Doraiswamy,Jefrey Petrella,Salvador Borges-Neto,Terence Z. Wong,Edward Coleman,Charles D. Smith,Greg Jicha,Peter A. Hardy,Partha Sinha,Elizabeth Oates,Gary R. Conrad,Anton P. Porsteinsson,Bonnie S. Goldstein,Kim Martin,Kelly M. Makino,M. Ismail,Connie Brand,Ruth A. Mulnard,Gaby Thai,Catherine Mc-Adams-Ortiz,Kyle B. Womack,Dana Mathews,Mary Quiceno,Allan I. Levey,James J. Lah,Janet S. Cellar,Jefrey Burns,Russell H. Swerdlow,William Brooks,Liana G. Apostolova,Kathleen Tingus,Ellen Woo,Daniel H.S. Silverman,Po Lu,George Bartzokis,Neill Graf-Radford,Francine Parftt,Tracy Kendall,Heather Johnson,Martin R. Farlow,Ann Marie Hake,Brandy R. Matthews,Jared R. Brosch,Scott Herring,Cynthia Hunt,Christopher H. van Dyck,Richard E. Carson,Martha G. MacAvoy,Pradeep Varma,Howard Chertkow,Howard Bergman,Chris Hosein,Sandra E. Black,Bojana Stefanovic,Curtis Caldwell,Ging Yuek Robin Hsiung,Howard Feldman,Benita Mudge,Michele Assaly,Elizabeth Finger,Stephen Pasternack,Irina Rachisky,Dick Trost,Andrew Kertesz,Charles Bernick,Donna Munic,M.-Marsel Mesulam,Kristine Lipowski,Sandra Weintraub,Borna Bonakdarpour,Diana Kerwin,Chuang Kuo Wu,Nancy Johnson,Carl H. Sadowsky,Teresa Villena,Raymond Scott Turner,Kathleen Johnson,Brigid Reynolds,Reisa A. Sperling,Keith A. Johnson,Gad A. Marshall,Jerome A. Yesavage,Joy L. Taylor,Barton Lane,Allyson C. Rosen,Jared R. Tinklenberg,Marwan N. Sabbagh,Christine M. Belden,Sandra W. Jacobson,Sherye A. Sirrel,Neil W. Kowall,Ronald J. Killiany,Andrew E. Budson,Alexander Norbash,Patricia Lynn Johnson,Thomas O. Obisesan,Saba Wolday,Joanne S. Allard,Alan J. Lerner,Paula Ogrocki,Curtis Tatsuoka,Parianne Fatica,Evan Fletcher,Pauline Maillard,John M Olichney,Charles DeCarli,Owen Carmichael,Smita Kittur,Michael Borrie,T. Y. Lee,Rob Bartha,Sterling C. Johnson,Sanjay Asthana,Cynthia M. Carlsson,Steven G. Potkin,Adrian Preda,Dana Nguyen,Pierre N. Tariot,Anna Burke,Nadira Trncic,Stephanie Reeder,Vernice Bates,Horacio Capote,Michelle Rainka,Douglas W. Scharre,Maria Kataki,Anahita Adeli,Earl A. Zimmerman,Dzintra Celmins,Alice D. Brown,Godfrey D. Pearlson,Karen Blank,Karen S. Anderson,Laura A. Flashman,Marc Seltzer,Mary L. Hynes,Robert B. Santulli,Kaycee M. Sink,Leslie Gordineer,Jef Williamson,Pradeep Garg,Franklin Watkins,Brian R. Ott,Henry W. Querfurth,Geofrey Tremont,Stephen Salloway,Paul Malloy,Stephen Correia,Howard J. Rosen,Bruce L. Miller,David C. Perry,Jacobo Mintzer,Kenneth M. Spicer,David Bachman,Nunzio Pomara,Raymundo Hernando,Antero Sarrael,Norman R. Relkin,Gloria Chaing,Michael Lin,Lisa D. Ravdin,Amanda Smith,Balebail Ashok Raj,Kristin Fargher +241 more
TL;DR: This work uses structural T1-w MRI to define morphological brain networks, and uses this architecture to discover morphological connectional biomarkers fingerprinting the difference between late MCI and AD stages, which included the right entorhinal cortex and right caudal middle frontal gyrus.
Journal ArticleDOI
Relationship of dementia screening tests with biomarkers of Alzheimer’s disease
TL;DR: The AD8 had superior sensitivity in detecting early stages of dementia compared with the Mini Mental State Examination and may improve strategies for detecting dementia in community settings where biomarkers may not be readily available, and may enrich clinical trial recruitment by increasing the likelihood that participants have underlying biomarker abnormalities.
Journal ArticleDOI
Regulation of blood flow in activated human brain by cytosolic NADH/NAD+ ratio
TL;DR: In awake human subjects, it is shown that by transiently raising blood pyruvate concentration during local increases in functional brain activity, a maneuver designed to reduce the cytosolic NADH/NAD+ ratio, the expected blood flow response measured with positron-emission tomography is significantly attenuated.