M
Martin H. Spalding
Researcher at Iowa State University
Publications - 85
Citations - 10264
Martin H. Spalding is an academic researcher from Iowa State University. The author has contributed to research in topics: Chlamydomonas reinhardtii & Chlamydomonas. The author has an hindex of 41, co-authored 81 publications receiving 9000 citations. Previous affiliations of Martin H. Spalding include University of Nebraska–Lincoln & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions
Sabeeha S. Merchant,Simon E. Prochnik,Olivier Vallon,Elizabeth H. Harris,Steven J. Karpowicz,George B. Witman,Astrid Terry,Asaf Salamov,Lillian K. Fritz-Laylin,Laurence Maréchal-Drouard,Wallace F. Marshall,Liang-Hu Qu,David R. Nelson,Anton A. Sanderfoot,Martin H. Spalding,Vladimir V. Kapitonov,Qinghu Ren,Patrick J. Ferris,Erika Lindquist,Harris Shapiro,Susan Lucas,Jane Grimwood,Jeremy Schmutz,Pierre Cardol,Pierre Cardol,Heriberto Cerutti,Guillaume Chanfreau,Chun-Long Chen,Valérie Cognat,Martin T. Croft,Rachel M. Dent,Susan K. Dutcher,Emilio Fernández,Hideya Fukuzawa,David González-Ballester,Diego González-Halphen,Armin Hallmann,Marc Hanikenne,Michael Hippler,William Inwood,Kamel Jabbari,Ming Kalanon,Richard Kuras,Paul A. Lefebvre,Stéphane D. Lemaire,Alexey V. Lobanov,Martin Lohr,Andrea L Manuell,Iris Meier,Laurens Mets,Maria Mittag,Telsa M. Mittelmeier,James V. Moroney,Jeffrey L. Moseley,Carolyn A. Napoli,Aurora M. Nedelcu,Krishna K. Niyogi,Sergey V. Novoselov,Ian T. Paulsen,Greg Pazour,Saul Purton,Jean-Philippe Ral,Diego Mauricio Riaño-Pachón,Wayne R. Riekhof,Linda A. Rymarquis,Michael Schroda,David B. Stern,James G. Umen,Robert D. Willows,Nedra F. Wilson,Sara L. Zimmer,Jens Allmer,Janneke Balk,Katerina Bisova,Chong-Jian Chen,Marek Eliáš,Karla C Gendler,Charles R. Hauser,Mary Rose Lamb,Heidi K. Ledford,Joanne C. Long,Jun Minagawa,M. Dudley Page,Junmin Pan,Wirulda Pootakham,Sanja Roje,Annkatrin Rose,Eric Stahlberg,Aimee M. Terauchi,Pinfen Yang,Steven G. Ball,Chris Bowler,Carol L. Dieckmann,Vadim N. Gladyshev,Pamela J. Green,Richard A. Jorgensen,Stephen P. Mayfield,Bernd Mueller-Roeber,Sathish Rajamani,Richard T. Sayre,Peter Brokstein,Inna Dubchak,David Goodstein,Leila Hornick,Y. Wayne Huang,Jinal Jhaveri,Yigong Luo,Diego Martinez,Wing Chi Abby Ngau,Bobby Otillar,Alexander Poliakov,Aaron Porter,Lukasz Szajkowski,Gregory Werner,Kemin Zhou,Igor V. Grigoriev,Daniel S. Rokhsar,Daniel S. Rokhsar,Arthur R. Grossman +118 more
TL;DR: Analyses of the Chlamydomonas genome advance the understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.
Journal ArticleDOI
High-efficiency TALEN-based gene editing produces disease-resistant rice
TL;DR: TALEN technology is exploited to edit a specific S gene in rice to thwart the virulence strategy of X. oryzae and thereby engineer heritable genome modifications for resistance to bacterial blight, a devastating disease in a crop that feeds half of the world’s population.
Journal ArticleDOI
Redesigning photosynthesis to sustainably meet global food and bioenergy demand
Donald R. Ort,Donald R. Ort,Sabeeha S. Merchant,Jean Alric,Alice Barkan,Robert E. Blankenship,Ralph Bock,Roberta Croce,Maureen R. Hanson,Julian M. Hibberd,Stephen P. Long,Thomas A. Moore,James V. Moroney,Krishna K. Niyogi,Krishna K. Niyogi,Martin A. J. Parry,Pamela Peralta-Yahya,Roger C. Prince,Kevin Redding,Martin H. Spalding,Klaas J. van Wijk,Wim F. J. Vermaas,Susanne von Caemmerer,Andreas P.M. Weber,Todd O. Yeates,Joshua S. Yuan,Xin-Guang Zhu +26 more
TL;DR: This work explores an array of prospective redesigns of plant systems at various scales aimed at increasing crop yields through improved photosynthetic efficiency and performance, and suggests some proposed redesigns are certain to face obstacles that will require alternate routes.
Journal ArticleDOI
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
Ting Li,Sheng Huang,Wen Zhi Jiang,David A. Wright,Martin H. Spalding,Donald P. Weeks,Bing Yang +6 more
TL;DR: The creation and initial characterization of a group of rare-cutting, site-specific DNA nucleases produced by fusion of the restriction enzyme FokI endonuclease domain (FN) with the high-specificity DNA-binding domains of AvrXa7 and PthXo1 are reported.
Journal ArticleDOI
Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
Ting Li,Sheng Huang,Xuefeng Zhao,David A. Wright,Susan Carpenter,Martin H. Spalding,Donald P. Weeks,Bing Yang +7 more
TL;DR: These studies expand the realm of verified TALEN activity from cultured human cells to an intact eukaryotic organism and suggest that low-cost, highly dependable dTALENs can assume a significant role for gene modifications of value in human and animal health, agriculture and industry.