R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
Papers
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Journal ArticleDOI
A Logistic Regression Model When Some Events Precede Treatment: The Effect of Thrombolytic Therapy for Acute Myocardial Infarction on the Risk of Cardiac Arrest
Christopher H. Schmid,Ralph B. D'Agostino,Ralph B. D'Agostino,John L. Griffith,Joni R. Beshansky,Harry P. Selker +5 more
TL;DR: The method is applied to develop a model to predict the probability that a patient with a myocardial infarction will have a sudden cardiac arrest within 48 hours of presentation to emergency medical services both when treated with thrombolysis and when not treated.
Book ChapterDOI
Optimal Identification of the Patient with Acute Myocardial Ischemia in the Emergency Room
TL;DR: This chapter reviews studies that have attempted to optimize AIHD diagnostic accuracy in the ER setting and suggests that even a modest improvement in admitting practices would yield substantial savings.
Journal ArticleDOI
Global risk assessment for cardiovascular disease and astute clinical judgement.
TL;DR: It is concluded that the Framingham (from the United States) and PROCAM (from Germany) risk functions overestimated the absolute risk of coronary heart disease in middle aged men from Belfast (with moderate risk) and France (with low risk).
Journal ArticleDOI
Compliance with expert population-based dietary guidelines and lower odds of carotid atherosclerosis in women: the Framingham Nutrition Studies
Barbara E. Millen,Paula A. Quatromoni,Byung-Ho Nam,Michael J. Pencina,Joseph F. Polak,Ruth W Kimokoti,Jose M. Ordovas,Ralph B. D'Agostino +7 more
TL;DR: Nutrient intake consistent with current expert population-based dietary guidelines and smoking abstinence are associated with lower odds of carotid atherosclerosis in women, suggesting areas for targeted primary CAD prevention.
Journal ArticleDOI
The Adjuvant Bordetella Colonization Factor A Attenuates Alum-Induced Th2 Responses and Enhances Bordetella pertussis Clearance from Mouse Lungs.
Jamie Jennings-Gee,Sally A. Quataert,Tridib Ganguly,Ralph B. D'Agostino,Rajendar Deora,Rajendar Deora,Purnima Dubey,Purnima Dubey +7 more
TL;DR: BcfA improves aPV-induced responses by modifying the alum-induced Th2-biased aPVs response toward Th1/Th17, which may allow better control of pertussis reemergence by reshaping immune responses to resemble those elicited by wPV immunization.