R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
Papers
More filters
Journal ArticleDOI
Performance of current guidelines for coronary heart disease prevention: optimal use of the Framingham-based risk assessment.
Timothy P. Murphy,Timothy P. Murphy,Rajoo Dhangana,Michael J. Pencina,Abdul Mueed Zafar,Abdul Mueed Zafar,Ralph B. D'Agostino +6 more
TL;DR: When used dichotomously as in current guidelines, sensitivity of the conventional 20% 10-year risk threshold for subsequent hCHD events is quite low, and lowering the threshold results in substantial increases in sensitivity with much smaller losses in specificity, even to a threshold as low as 5%.
Journal ArticleDOI
Development of Appropriate Coronary Heart Disease Risk Prediction Models in HIV-Infected Patients
Morris Schambelan,Peter W.F. Wilson,Kevin E. Yarasheski,W. Todd Cade,Victor G. Davila-Roman,Ralph B. D'Agostino,Tarek Helmy,Matthew Law,Kristin Mondy,Sharon Nachman,Linda R. Peterson,Signe Westring Worm +11 more
TL;DR: Traditional risk factors may operate in the same manner in HIV patients as in the general population, but there may still be a need to identify and evaluate HIV-specific CHD risk factors and equations, to refine existing CHD prediction equations, and to develop new HIV- specific CHD Prediction equations for adults, adolescents, and children.
Journal ArticleDOI
Retrospective Analysis of Cisplatin Nephrotoxicity in Patients With Head and Neck Cancer Receiving Outpatient Treatment With Concurrent High-dose Cisplatin and Radiotherapy.
Jennifer Faig,Michael Haughton,Richard C. Taylor,Ralph B. D'Agostino,Megan J. Whelen,Kori A. Porosnicu Rodriguez,Marcelo Bonomi,Mariana Murea,Mercedes Porosnicu +8 more
TL;DR: An outpatient high-dose cisplatin protocol aimed at preventing nephrotoxicity and the results of its utilization in patients with SCCHN treated with concurrent radiotherapy are analyzed to highlight the importance of close monitoring and additional replacement of water and electrolytes as needed.
DatasetDOI
Female Sexual Function Index
R. Rosen,Candace Brown,Julia R. Heiman,S. Leiblum,C. Meston,Ridwan Shabsigh,David Ferguson,Ralph B. D'Agostino +7 more
Journal ArticleDOI
The Effectiveness of Regionalized Burn Care: An Analysis of 6,873 Burn Admissions in North Carolina from 2000 to 2007
James H. Holmes,Jeffrey E Carter,Lucas P. Neff,Bruce A. Cairns,Ralph B. D'Agostino,Leah Griffin,J. Wayne Meredith +6 more
TL;DR: This is the most comprehensive study of its kind and demonstrates that ABA burn center referral criteria are not always used for effective regionalized burn care or to ensure the best possible outcomes.