R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Intensity and Amount of Physical Activity in Relation to Insulin Sensitivity: The Insulin Resistance Atherosclerosis Study
Elizabeth J. Mayer-Davis,Ralph B. D'Agostino,Andrew J. Karter,Steven M. Haffner,Marian Rewers,Mohammed F. Saad,Richard N. Bergman +6 more
TL;DR: Increased participation in nonvigorous as well as overall and vigorous physical activity was associated with significantly higher insulin sensitivity, and these findings lend further support to current public health recommendations for increased moderate-intensity physical activity on most days.
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Non‐inferiority trials: design concepts and issues – the encounters of academic consultants in statistics
Ralph B. D'Agostino,Ralph B. D'Agostino,Joseph M. Massaro,Joseph M. Massaro,Lisa M. Sullivan +4 more
TL;DR: The non‐inferiority trial is appropriate for evaluation of the efficacy of an experimental treatment versus an active control when it is hypothesized that the experimental treatment may not be superior to a proven effective treatment, but is clinically and statistically not inferior in effectiveness.
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Tests for departure from normality. Empirical results for the distributions of b2 and √b1
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Increasing Cardiovascular Disease Burden Due to Diabetes Mellitus The Framingham Heart Study
Caroline S. Fox,Sean Coady,Paul D. Sorlie,Ralph B. D'Agostino,Michael J. Pencina,Ramachandran S. Vasan,James B. Meigs,Daniel Levy,Peter J. Savage +8 more
TL;DR: The proportion of CVD attributable to diabetes mellitus has increased over the past 50 years in Framingham, emphasizing the need for increased efforts to prevent DM and to aggressively treat and control CVD risk factors among those with DM.
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Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: a randomized trial.
Theodore Mazzone,Peter M. Meyer,Steven B. Feinstein,Michael H. Davidson,George T. Kondos,Ralph B. D'Agostino,Alfonso Perez,Jean Claude Provost,Steven M. Haffner +8 more
TL;DR: Over an 18-month treatment period in patients with type 2 DM, pioglitazone slowed progression of CIMT compared with glimepiride and was similar across prespecified subgroups based on age, sex, systolic blood pressure, duration of DM, body mass index, HbA(1c) value, and statin use.