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Ralph B. D'Agostino

Researcher at Wake Forest University

Publications -  1336
Citations -  250792

Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.

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Journal Article

Metal ion-dependent hydrogen peroxide-induced DNA damage is more sequence specific than metal specific

Henry Rodriguez, +4 more
- 15 Jun 1997 - 
TL;DR: It is concluded that during H2O2 in vivo treatment of cells, metal ions are freed from the cytoplasm to migrate into the nucleus and supply the redox cycling ligands necessary for oxidative base damage.
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Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk.

Geoffrey H. Tofler, +7 more
- 01 Nov 2002 - 
TL;DR: Folic acid and other homocysteine lowering therapies may decrease cardiac events through a reduction in thrombotic tendency, as indicated by increased PAI-1 and TPA antigen levels.
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Use of composite endpoints in clinical trials

Abdul J. Sankoh, +2 more
- 30 Nov 2014 - 
TL;DR: The utility of composite endpoints in clinical trials and some of the common approaches for dealing with multiplicity arising from their use are discussed.
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Simulation probability points of b2 for small samples

Ralph B. D'Agostino, +1 more
- 01 Dec 1971 - 
TL;DR: A table of percentiles of b2, the fourth standardized sample moment, applicable for samples of size 50 or less is given in this paper, which can be used for testing the hypothesis of normality against alternatives of nonnormality due to kurtosis.
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Factor VII Gene Polymorphism, Factor VII Levels, and Prevalent Cardiovascular Disease The Framingham Heart Study

DaLi Feng, +11 more
- 01 Feb 2000 - 
TL;DR: In the Framingham Heart Study, the Arg/Gln polymorphism was significantly associated with factor VII antigen levels, and the strength of the association suggests that genetic variation plays an important role in determining factor VII levels.