R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Factor Analysis of Metabolic Syndrome Using Directly Measured Insulin Sensitivity The Insulin Resistance Atherosclerosis Study
Anthony J.G. Hanley,Andrew J. Karter,Andreas Festa,Ralph B. D'Agostino,Lynne E. Wagenknecht,Peter J. Savage,Russell P. Tracy,Mohammed F. Saad,Steven M. Haffner +8 more
TL;DR: Investigation of the clustering of physiologic variables using data from 1,087 nondiabetic participants in the Insulin Resistance Atherosclerosis Study (IRAS) identified two underlying factors among a group of metabolic syndrome variables in this dataset.
Journal ArticleDOI
Marital status, marital strain, and risk of coronary heart disease or total mortality: The Framingham offspring study.
Elaine D. Eaker,Lisa M. Sullivan,Margaret Kelly-Hayes,Ralph B. D'Agostino,Emelia J. Benjamin +4 more
TL;DR: The study suggests that marital communication, conflict, and strain are associated with adverse health outcomes and further research into the influence of marital stress on health is merited.
Journal ArticleDOI
Low-Grade Albuminuria and the Risks of Hypertension and Blood Pressure Progression
Thomas J. Wang,Jane C. Evans,James B. Meigs,Nader Rifai,Caroline S. Fox,Caroline S. Fox,Ralph B. D'Agostino,Ralph B. D'Agostino,Daniel Levy,Ramachandran S. Vasan,Ramachandran S. Vasan +10 more
TL;DR: Urinary albumin excretion predicts blood pressure progression in nondiabetic, nonhypertensive individuals incrementally over established risk factors and at levels well below the conventional threshold for microalbuminuria, which may be a useful biomarker for identifying individuals most likely to develop hypertension.
Journal ArticleDOI
Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator
Yan Jiao,John Wilkinson,Xiumin Di,Wei Wang,Heather Hatcher,Nancy D. Kock,Ralph B. D'Agostino,Mary Ann Knovich,Frank M. Torti,Suzy V. Torti +9 more
TL;DR: Curcumin exerted profound 2 effects on systemic iron, inducing a dose-dependent decline in hematocrit, hemoglobin, serum iron, and transferrin saturation, the appearance of microcytic anisocytotic red blood cells, and decreases in spleen and liver iron content.
Journal ArticleDOI
Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis
David Wormser,Emanuele Di Angelantonio,Stephen Kaptoge,Angela M. Wood,Pei Gao,Qi Sun,Qi Sun,Göran Walldius,Randi Selmer,W. M. Monique Verschuren,H. Bas Bueno-de-Mesquita,Gunnar Engström,Paul M. Ridker,Inger Njølstad,Hiroyasu Iso,Ingar Holme,Simona Giampaoli,Hugh Tunstall-Pedoe,J. Michael Gaziano,Eric J. Brunner,Frank Kee,Alberto Tosetto,Christa Meisinger,Hermann Brenner,Pierre Ducimetière,Peter H. Whincup,Robert W. Tipping,Ian Ford,Peter Cremer,Albert Hofman,Lars Wilhelmsen,Robert Clarke,Ian H. de Boer,Ian H. de Boer,J. Wouter Jukema,J. Wouter Jukema,Alejandro Marín Ibañez,Debbie A Lawlor,Ralph B. D'Agostino,Beatriz L. Rodriguez,Edoardo Casiglia,Coen D.A. Stehouwer,Leon A. Simons,Paul J. Nietert,Elizabeth Barrett-Connor,Demosthenes B. Panagiotakos,Cecilia Björkelund,Timo Strandberg,Timo Strandberg,Sylvia Wassertheil-Smoller,Dan G. Blazer,Tom W. Meade,Lennart Welin,Kurt Svärdsudd,Mark Woodward,Aulikki Nissinen,Daan Kromhout,Torben Jørgensen,Reijo S. Tilvis,Reijo S. Tilvis,Jack M. Guralnik,Annika Rosengren,James O. Taylor,Stefan Kiechl,Gilles R. Dagenais,F. Gerry R. Fowkes,Robert B. Wallace,Kay-Tee Khaw,Jonathan A. Shaffer,Marjolein Visser,Jussi Kauhanen,Jukka T. Salonen,John Gallacher,John Gallacher,Yoav Ben-Shlomo,Yoav Ben-Shlomo,Akihiko Kitamura,Johan Sundström,Patrik Wennberg,Yutaka Kiyohara,Makoto Daimon,Agustín Gómez de la Cámara,Jackie A. Cooper,Altan Onat,Richard B. Devereux,Kenneth J. Mukamal,Kenneth J. Mukamal,Rachel Dankner,Matthew Knuiman,Carlos J. Crespo,Ron T. Gansevoort,Uri Goldbourt,Børge G. Nordestgaard,Jonathan E. Shaw,Michael E. Mussolino,Hidaeki Nakagawa,Astrid E. Fletcher,Lewis H. Kuller,Richard F. Gillum,Vilmundur Gudnason,Gerd Assmann,Nicholas J. Wald,P. Jousilahti,Philip Greenland,Maurizio Trevisan,Hanno Ulmer,Adam S. Butterworth,Aaron R. Folsom,George Davey-Smith,Frank B. Hu,John Danesh,Lara M. Simpson,Ingmar Jungner,Ellen W. Demerath,Nora Franceschini,Pamela L. Lutsey,Christos Pitsavos,Christina Chrysohoou,Christodoulos Stefanadis,Robert C. Atkins,Paul Zimmet,Elizabeth L M Barr,S. Goya Wannamethee,Richard W Morris,Johann Willeit,Siegfried Weger,Friedrich Oberhollenzer,Shah Ebrahim,John Yarnell,Valérie Tikhonoff,Christina M. Shay,Daniel B. Garside,Susan E. Sutherland,David Bachman,Julian E. Keil,Jorge R. Kizer,Bruce M. Psaty,Anne Tybjærg-Hansen,Gorm B. Jensen,Peter Schnohr,Luigi Palmieri,Salvatore Panico,Lorenza Pilotto,Diego Vanuzzo,Judith Simons,John McCallum,Yechiel Friedlander,Caroline L. Phillips,Frank J. Kohout,Joan Cornoni-Huntley,Nicholas J. Wareham,Ben Schöttker,Heiko Müller,Dietrich Rothenbacher,Jan-Håkan Jansson,Chiara Donfrancesco,Erkki Vartiainen,Kennet Harald,V V Salomaa,Ramachandran S. Vasan,Caroline S. Fox,Michael J. Pencina,Toshihide Oizumi,Takamasa Kayama,Takeo Kato,Else-Marie Bladbjerg,Lars Alling Møller,Jørgen Jespersen,Angela Chetrit,Flora Lubin,Henry Eriksson,Georgios Lappas,Calle Bengtsson,Lauren Lissner,Dorothea Nagel,Tatu A. Miettinen,Hisatomi Arima,Yasufumi Doi,Toshiharu Ninomiya,Jacqueline M. Dekker,Giel Nijpels,Eric B. Rimm,Walter C. Willett,Kazumasa Yamagishi,Hiroyuki Noda,Sudhir Kurl,Tomi-Pekka Tuomainen,Jan Poppelaars,Dorly J. H. Deeg,Bianca De Stavola,Bo Hedblad,Peter Nilsson,Anneke Blokstra,Steven J Shea,Barbara Thorand,Wolfgang Koenig,Angela Döring,Dorothea Nitsch,Greg Grandits,Aage Tverdal,Wenche Nystad,Joann E. Manson,Susan E. Hankinson,Kenneth A. Bauer,Karina W. Davidson,Susan Kirkland,Daichi Shimbo,Shinichi Sato,Katsuyuki Miura,Masaru Sakurai,Xavier Jouven,Stephan J. L. Bakker,Pim van der Harst,Hans L. Hillege,Mario R. Garcia-Palmieri,Philippe Amouyel,Dominique Arveiler,Jean Ferrières,Helmut Schulte,Anton J. M. de Craen,Naveed Sattar,David J. Stott,Bernard Cantin,Benoît Lamarche,Jean-Pierre Després,Jaclyn Bergstrom,Richele R. Bettencourt,Catherine Buisson,Thor Aspelund,Gunnar Sigurdsson,Bolli Thorsson,M. Arfan Ikram,Henning Tiemeier,Jacqueline C.M. Witteman,Roger Tavendale,Gordon D.O. Lowe,Jeun Liang Yeh,Tauqeer Ali,Darren Calhoun,Günay Can,Koshi Nakamura,Yuko Morikawa,Ellisiv B. Mathiesen,Maja-Lisa Løchen,Tom Wilsgaard,Erik Ingelsson,Karl Michaëlsson,Tommy Cederholm,Julie E. Buring,G. Diem,Hans Concin,Francesco Rodeghiero,Michael Marmot,Martin Shipley Mika Kivimaki,Michele Robertson,Edith J. M. Feskens,Johanna M. Geleijnse,Matthew G. Walker,Sarah Watson,Myriam Alexander,Oscar H. Franco,Reeta Gobin,Philip C Haycock,Sreenivasa Rao Kondapally Seshasai,Sarah Lewington,Lisa Pennells,Eleni Rapsomaniki,Nadeem Sarwar,Alexander M. W. Cargill Thompson,Simon G. Thompson,Ian R. White,Xiaohui Zhao +271 more
TL;DR: Adult height has directionally opposing relationships with risk of death from several different major causes of chronic diseases.