R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study).
Luc Djoussé,Daniel Levy,Alan Herbert,Alan Herbert,Peter W.F. Wilson,Ralph B. D'Agostino,L. Adrienne Cupples,Samer Karamohamed,R. Curtis Ellison +8 more
TL;DR: In this paper, the effects of alcohol dehydrogenase 1C (ADH1C) polymorphisms on the association between alcohol consumption and CVD were investigated in the Framingham Offspring Study.
Journal ArticleDOI
Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx
Hugo Jimenez,Minghui Wang,Jacquelyn W. Zimmerman,Michael J. Pennison,Sambad Sharma,Trevor Surratt,Zhi Xiang Xu,Ivan A. Brezovich,Devin Absher,Richard M. Myers,Barry DeYoung,David L. Caudell,Dongquan Chen,Hui-Wen Lo,Hui Kuan Lin,Dwayne W. Godwin,Michael Olivier,Anand Ghanekar,Kui Chen,Lance D. Miller,Yijian Gong,Myles Capstick,Ralph B. D'Agostino,Reginald F. Munden,Philippe Merle,Alexandre Barbault,Arthur W. Blackstock,Herbert L. Bonkovsky,Guang Yu Yang,Guangxu Jin,Liang Liu,Wei Zhang,Kounosuke Watabe,Carl Blackman,Boris Pasche +34 more
TL;DR: Intrabuccally-administered AM RF EMF is a systemic therapy that selectively block the growth of HCC cells and pronounced inhibitory effects on cancer stem cells may explain the exceptionally long responses observed in several patients with advanced HCC.
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Shared decision-making among caregivers and health care providers of youth with type 1 diabetes.
Jessica M. Valenzuela,Laura B. Smith,Jeanette M. Stafford,Ralph B. D'Agostino,Jean M. Lawrence,Joyce P. Yi-Frazier,Michael Seid,Lawrence M. Dolan +7 more
TL;DR: It is suggested that youth whose caregivers report greater SDM may show benefits in terms of self-care and glycemic control and how best to identify youth and families with low SDM in order to improve care.
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Insulin sensitivity and arterial stiffness in youth with type 1 diabetes: the SEARCH CVD study.
Amy S. Shah,Sandra R. Black,R. Paul Wadwa,Sarah J. Schmiege,Nora F. Fino,Jennifer W. Talton,Ralph B. D'Agostino,Richard F. Hamman,Elaine M. Urbina,Lawrence M. Dolan,Stephen R. Daniels,Santica M. Marcovina,Dana Dabelea +12 more
TL;DR: Lower insulin sensitivity at baseline appears to be an important risk factor for increased arterial stiffness over time in youth with T1D, and is identified a potentially modifiable therapeutic target.
Journal Article
A Proposal for Integrated Efficacy-to-Effectiveness (E2E) Clinical Trials
Harry P. Selker,Kenneth A. Oye,Hans-Georg Eichler,Norman Stockbridge,Cyrus R. Mehta,Kenneth I. Kaitin,Newell E. McElwee,Peter K. Honig,John K. Erban,Ralph B. D'Agostino +9 more
TL;DR: An E2E approach may improve the evidentiary basis for selecting treatments, expand understanding of the effectiveness of treatments in subgroups with particular clinical features, and foster incorporation of effectiveness information into regulatory processes.