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Ralph B. D'Agostino

Researcher at Wake Forest University

Publications -  1336
Citations -  250792

Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.

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Robustness and power of analysis of covariance applied to ordinal scaled data as arising in randomized controlled trials.

TL;DR: The robustness and power of various versions of parametric analysis of covariance applied to small samples of ordinal scaled data are investigated through computer simulation and the hierarchical approach which first tests for homogeneity of regression slopes and then fits separate slopes if there is significant non-homogeneity produced significance levels that exceeded the nominal levels.
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Platelet Glycoprotein IIIa PlA Polymorphism, Fibrinogen, and Platelet Aggregability The Framingham Heart Study

TL;DR: Higher fibrinogen levels were associated with increased platelet aggregability, however, the association between fibr inogen and platelets aggregability was genotype specific, which may be responsible for the conflicting findings regarding PlA genotype and platelet aggregation.
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Mutually Exclusive Inactivation of DMP1 and ARF/p53 in Lung Cancer

TL;DR: DMP1 is a pivotal tumor suppressor for both human and murine lung cancers and was found in mutually exclusive fashion with LOH of INK4a/ARF or that of P53.
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Recommended revisions to American Dental Association guidelines for acceptance of chemotherapeutic products for gingivitis control

TL;DR: Suggested revisions to the American Dental Association's 1985 guidelines for acceptance of anti-gingivitis chemotherapeutic agents articulate certain aspects of study design which were implicit in the 1985 guidelines, clarify language on cross-over designs and independence of studies, and recommend use of a United States population in at least one trial supporting a product.
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Dietary quality predicts adult weight gain: findings from the Framingham Offspring Study.

TL;DR: The hypothesis that dietary quality, measured by adherence to the Dietary Guidelines, was related to weight change in adults was found to be correct.