R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model
TL;DR: The results support the use of flagellin in neonates as an adjuvant that promotes long-lived, high affinity antibody responses that result in long term immune responses in Neonates.
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Research Pearls: The Significance of Statistics and Perils of Pooling. Part 2: Predictive Modeling.
TL;DR: The focus of predictive modeling or predictive analytics is to use statistical techniques to predict outcomes and/or the results of an intervention or observation for patients that are conditional on a specific set of measurements taken on the patients prior to the outcomes occurring.
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Pioglitazone-Mediated Changes in Lipoprotein Particle Composition Are Predicted by Changes in Adiponectin Level in Type 2 Diabetes
Susan Sam,Steven M. Haffner,Michael H. Davidson,Ralph B. D'Agostino,Alfonso Perez,Theodore Mazzone +5 more
TL;DR: Increased adiponectin contributed to treatment-related benefit in lipoprotein cardiovascular disease risk factors in obese diabetic subjects treated with pioglitazone, and this results provide support for a model that mechanistically links changes in adiponECTin level to changes inlipoprotein composition in humans.
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International Validation of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention in Post-MI Patients: A Collaborative Analysis of the Chronic Kidney Disease Prognosis Consortium and the Risk Validation Scientific Committee.
Yejin Mok,Shoshana H. Ballew,Lori D. Bash,Deepak L. Bhatt,William E. Boden,Marc P. Bonaca,Juan Jesus Carrero,Josef Coresh,Ralph B. D'Agostino,C Raina Elley,F. Gerry R. Fowkes,Sun Ha Jee,Csaba P. Kovesdy,Kenneth W. Mahaffey,Girish N. Nadkarni,Eric D. Peterson,Yingying Sang,Kunihiro Matsushita +17 more
TL;DR: TRS2°P, a simple scoring system with 9 routine clinical factors, was modestly predictive of secondary events when applied in patients with recent myocardial infarction from diverse clinical and geographic settings.
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Robustness of Location Estimators under Changes of Population Kurtosis
TL;DR: In this article, the robustness of various estimators of the mean for two families of symmetric distributions (exponential power and t) indexed by the kurtosis γ and Hogg's (1972) measure of tail thickness Q was investigated.