R
Ralph B. D'Agostino
Researcher at Wake Forest University
Publications - 1336
Citations - 250792
Ralph B. D'Agostino is an academic researcher from Wake Forest University. The author has contributed to research in topics: Framingham Heart Study & Framingham Risk Score. The author has an hindex of 226, co-authored 1287 publications receiving 229636 citations. Previous affiliations of Ralph B. D'Agostino include VA Boston Healthcare System & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Stroke Severity in Atrial Fibrillation The Framingham Study
Huey-Juan Lin,Philip A. Wolf,Margaret Kelly-Hayes,Alexa S. Beiser,Carlos S. Kase,Emelia J. Benjamin,Ralph B. D'Agostino +6 more
TL;DR: Ischemic stroke associated with AF was nearly twice as likely to be fatal as non-AF stroke, Recurrence was more frequent, and functional deficits were more likely to been severe among survivors.
Journal ArticleDOI
Presentation of multivariate data for clinical use: The Framingham Study risk score functions.
TL;DR: An effort to make available a tool for clinicians to aid in their decision‐making process regarding treatment and to assist them in motivating patients toward healthy behaviours is made available.
Journal ArticleDOI
Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis
Jacob Selhub,Paul F. Jacques,Andrew G. Bostom,Ralph B. D'Agostino,Peter W.F. Wilson,Albert J. Belanger,Daniel H. O'Leary,Philip A. Wolf,Ernst J. Schaefer,Irwin H. Rosenberg +9 more
TL;DR: High plasma homocysteine concentrations and low concentrations of folate and vitamin B6, through their role in homocy steine metabolism, are associated with an increased risk of extracranial carotid-artery stenosis in the elderly.
Journal ArticleDOI
Prediction of Lifetime Risk for Cardiovascular Disease by Risk Factor Burden at 50 Years of Age
Donald M. Lloyd-Jones,Eric P. Leip,Eric P. Leip,Martin G. Larson,Ralph B. D'Agostino,Ralph B. D'Agostino,Alexa S. Beiser,Alexa S. Beiser,Peter W.F. Wilson,Peter W.F. Wilson,Philip A. Wolf,Philip A. Wolf,Daniel Levy,Daniel Levy +13 more
TL;DR: The absence of established risk factors at 50 years of age is associated with very low lifetime risk for CVD and markedly longer survival, which should promote efforts aimed at preventing development of risk factors in young individuals.
Journal ArticleDOI
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.
John Danesh,Sarah Lewington,Simon G. Thompson,Lowe Gdo.,Rory Collins,John B. Kostis,Angela Wilson,Aaron R. Folsom,K. Wu,M. Benderly,Uri Goldbourt,Johann Willeit,Stefan Kiechl,Yarnell Jwg.,P. M. Sweetnam,P. Elwood,Mary Cushman,Bruce M. Psaty,Russell P. Tracy,Anne Tybjærg-Hansen,F. Haverkate,De Maat Mpm.,Fowkes Fgr.,Amanda J Lee,F.B. Smith,Veikko Salomaa,Kennet Harald,V. Rasi,E. Vahtera,P. Jousilahti,Juha Pekkanen,Ralph B. D'Agostino,W B Kannel,Wilson Pwf.,Geoffrey H. Tofler,Carmen Luisa Arocha-Piñango,Alvaro Rodríguez-Larralde,Elena Nagy,Mercedes E Mijares,Raul Espinosa,E Rodriquez-Roa,Elena Ryder,María Diez-Ewald,Gilberto Campos,Virginia Fernández,Enrique Torres,Roberto Marchioli,Franco Valagussa,Annika Rosengren,Lars Wilhelmsen,Georgios Lappas,Henry Eriksson,Peter Cremer,Dorothea Nagel,J D Curb,Beatriz L. Rodriguez,K Yano,Jukka T. Salonen,Kristiina Nyyssönen,Tomi-Pekka Tuomainen,Bo Hedblad,P. Lind,H. Loewel,Wolfgang Koenig,Tom W. Meade,J.A. Cooper,B L De Stavola,C. Knottenbelt,George J. Miller,Kenneth A. Bauer,Robert D. Rosenberg,S. Sato,A. Kitamura,Yoshihiko Naito,Hiroyasu Iso,T. Palosuo,Pierre Ducimetière,Philippe Amouyel,Dominique Arveiler,Alun Evans,Jean Ferrières,Irène Juhan-Vague,Annie Bingham,Helmut Schulte,Gerd Assmann,Bernard Cantin,Benoît Lamarche,Jean-Pierre Després,Gilles R. Dagenais,Hugh Tunstall-Pedoe,Mark Woodward,Yoav Ben-Shlomo +91 more
TL;DR: In this article, a large-scale individual participant meta-analysis was conducted to assess the relationship of fibrinogen levels with risk of major vascular and non-vascular outcomes based on individual participant data.