R
Richard S. Judson
Researcher at United States Environmental Protection Agency
Publications - 231
Citations - 25081
Richard S. Judson is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: High-Throughput Screening Assays & Population. The author has an hindex of 69, co-authored 220 publications receiving 22147 citations. Previous affiliations of Richard S. Judson include Sandia National Laboratories & University of Houston.
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Journal ArticleDOI
A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae
Peter Uetz,Loic Giot,Gerard Cagney,Traci A. Mansfield,Richard S. Judson,James R. Knight,Daniel Lockshon,Vaibhav A. Narayan,Maithreyan Srinivasan,Pascale Pochart,Alia Qureshi-Emili,Ying Li,Brian C. Godwin,Diana Conover,Theodore S. Kalbfleisch,Govindan Vijayadamodar,Meijia Yang,Mark Johnston,Stanley Fields,Jonathan M. Rothberg +19 more
TL;DR: Examination of large-scale yeast two-hybrid screens reveals interactions that place functionally unclassified proteins in a biological context, interactions between proteins involved in the same biological function, and interactions that link biological functions together into larger cellular processes.
Journal ArticleDOI
Teaching lasers to control molecules.
TL;DR: This work simulates an apparatus that learns to excite specified rotational states in a diatomic molecule and uses a learning procedure to direct the production of pulses based on fitness'' information provided by a laboratory measurement device.
Journal ArticleDOI
Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness.
Connie M. Drysdale,Dennis W. McGraw,Catharine B. Stack,J. Claiborne Stephens,Richard S. Judson,Krishnan Nandabalan,Kevin M. Arnold,Gualberto Ruaño,Stephen B. Liggett +8 more
TL;DR: The results indicate that the unique interactions of multiple SNPs within a haplotype ultimately can affect biologic and therapeutic phenotype and that individual SNPs may have poor predictive power as pharmacogenetic loci.
Journal ArticleDOI
Haplotype variation and linkage disequilibrium in 313 human genes.
J. Claiborne Stephens,Julie A. Schneider,Debra A. Tanguay,Julie . Choi,Tara Acharya,Scott E. Stanley,Ruhong Jiang,Chad Messer,Anne Chew,Jin-Hua Han,Jicheng Duan,Janet L. Carr,Min Seob Lee,Beena Koshy,A. Madan Kumar,Ge Zhang,William R. Newell,Andreas Windemuth,Chuanbo Xu,Theodore S. Kalbfleisch,Sandra L. Shaner,Kevin M. Arnold,Vincent P. Schulz,Connie M. Drysdale,Krishnan Nandabalan,Richard S. Judson,Gualberto Ruaño,Gerald F. Vovis +27 more
TL;DR: Pairs of SNPs exhibited variability in the degree of linkage disequilibrium that was a function of their location within a gene, distance from each other, population distribution, and population frequency.
Journal ArticleDOI
The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
Leming Shi,Gregory Campbell,Wendell D. Jones,Fabien Campagne,Zhining Wen,Stephen J. Walker,Zhenqiang Su,Tzu Ming Chu,Federico Goodsaid,Lajos Pusztai,John D. Shaughnessy,André Oberthuer,Russell S. Thomas,Richard S. Paules,Mark R. Fielden,Bart Barlogie,Weijie Chen,Pan Du,Matthias Fischer,Cesare Furlanello,Brandon D. Gallas,Xijin Ge,Dalila B. Megherbi,W. Fraser Symmans,May D. Wang,John Zhang,Hans Bitter,Benedikt Brors,Pierre R. Bushel,Max Bylesjö,Minjun Chen,Jie Cheng,Jing Cheng,Jeff W. Chou,Timothy Davison,Mauro Delorenzi,Youping Deng,Viswanath Devanarayan,David J. Dix,Joaquín Dopazo,Kevin C. Dorff,Fathi Elloumi,Jianqing Fan,Shicai Fan,Xiaohui Fan,Hong Fang,Nina Gonzaludo,Kenneth R. Hess,Huixiao Hong,Jun Huan,Rafael A. Irizarry,Richard S. Judson,Dilafruz Juraeva,Samir Lababidi,Christophe G. Lambert,Li Li,Yanen Li,Zhen Li,Simon Lin,Guozhen Liu,Edward K. Lobenhofer,J. Luo,Wen Luo,Matthew N. McCall,Yuri Nikolsky,Gene Pennello,Roger Perkins,Reena Philip,Vlad Popovici,Nathan D. Price,Feng Qian,Andreas Scherer,Tieliu Shi,Weiwei Shi,Jaeyun Sung,Danielle Thierry-Mieg,Jean Thierry-Mieg,Venkata Thodima,Johan Trygg,Lakshmi Vishnuvajjala,Sue Jane Wang,Jianping Wu,Yichao Wu,Qian Xie,Waleed A. Yousef,Liang Zhang,Xuegong Zhang,Sheng Zhong,Yiming Zhou,Sheng Zhu,Dhivya Arasappan,Wenjun Bao,Anne Bergstrom Lucas,Frank Berthold,Richard J. Brennan,Andreas Buness,Jennifer G. Catalano,Chang Chang,Rong Chen,Yiyu Cheng,Jian Cui,Wendy Czika,Francesca Demichelis,Xutao Deng,Damir Dosymbekov,Roland Eils,Yang Feng,Jennifer Fostel,Stephanie Fulmer-Smentek,James C. Fuscoe,Laurent Gatto,Weigong Ge,Darlene R. Goldstein,Li Guo,Donald N. Halbert,Jing Han,Stephen C. Harris,Christos Hatzis,Damir Herman,Jianping Huang,Roderick V. Jensen,Rui Jiang,Charles D. Johnson,Giuseppe Jurman,Yvonne Kahlert,Sadik A. Khuder,Matthias Kohl,Jianying Li,Li Lee,Menglong Li,Quan Zhen Li,Shao Li,Zhiguang Li,Jie Liu,Ying Liu,Zhichao Liu,Lu Meng,Manuel Madera,Francisco Martinez-Murillo,Ignacio Medina,Joseph Meehan,K. Miclaus,Richard A. Moffitt,David Montaner,Piali Mukherjee,George Mulligan,Padraic Neville,Tatiana Nikolskaya,Baitang Ning,Grier P. Page,Joel S. Parker,R. Mitchell Parry,Xuejun Peng,Ron L. Peterson,John H. Phan,Brian Quanz,Yi Ren,Samantha Riccadonna,Alan H. Roter,Frank W. Samuelson,Martin Schumacher,Joseph D. Shambaugh,Qiang Shi,Richard Shippy,Shengzhu Si,Aaron Smalter,Christos Sotiriou,Mat Soukup,Frank Staedtler,Guido Steiner,Todd H. Stokes,Qinglan Sun,Pei Yi Tan,Rong Tang,Zivana Tezak,Brett T. Thorn,Marina Tsyganova,Yaron Turpaz,S. Vega,Roberto Visintainer,Juergen Von Frese,Charles Wang,Eric Wang,Junwei Wang,Wei Wang,Frank Westermann,James C. Willey,Matthew Woods,Shujian Wu,Nianqing Xiao,Joshua Xu,Lei Xu,Lun Yang,Xiao Zeng,Jialu Zhang,Li Zheng,Min Zhang,Chen Zhao,Raj K. Puri,Uwe Scherf,Weida Tong,Russell D. Wolfinger +201 more
TL;DR: P predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung or liver toxicity in rodents, or of breast cancer, multiple myeloma or neuroblastoma in humans are generated.