S
Satoru Miyano
Researcher at Tokyo Medical and Dental University
Publications - 874
Citations - 45801
Satoru Miyano is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 84, co-authored 811 publications receiving 38723 citations. Previous affiliations of Satoru Miyano include University of Paderborn & Institute of Medical Science.
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Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types
Akihiro Fujimoto,Masashi Fujita,Takanori Hasegawa,Nagahide Matsubara,Kazuhiro Maejima,Kaoru Nakano,Aya Oku-Sasaki,Jing Hao Wong,Yuichi Shiraishi,Satoru Miyano,Seiya Imoto,Naohiro Tomita,Michael R. Stratton,Steven G Rosen,Hidewaki Nakagawa +14 more
TL;DR: An insertion and deletion caller is developed that takes into consideration the error patterns of different types of microsatellites and suggests that germline variations and somatic mutation rates were correlated, which provides a comprehensive picture of mutations in the microsatellite regions.
Journal ArticleDOI
Discrimination of prediction models between cold-heat and deficiency-excess patterns.
Ayako Maeda-Minami,Tetsuhiro Yoshino,Kotoe Katayama,Yuko Horiba,Hiroaki Hikiami,Yutaka Shimada,Takao Namiki,Eiichi Tahara,Kiyoshi Minamizawa,Shin-ichi Muramatsu,Rui Yamaguchi,Seiya Imoto,Satoru Miyano,Hideki Mima,Masaru Mimura,Tomonori Nakamura,Kenji Watanabe +16 more
TL;DR: BMI and blood pressure, and subjective symptoms of cold or heat sensations were the most important items in the prediction models of deficiency-excess pattern and of cold-heat patterns, respectively.
Journal ArticleDOI
Comprehensive Analysis of Aberrant RNA Splicing in Myelodysplastic Syndromes
Yusuke Shiozawa,Sato Sato-Otsubo,Anna Gallì,Kenichi Yoshida,Tetsuichi Yoshizato,Yusuke Sato,Keisuke Kataoka,Masashi Sanada,Yuichi Shiraishi,Kenichi Chiba,Satoru Miyano,Luca Malcovati,Mario Cazzola,Seishi Ogawa +13 more
TL;DR: It is found that SF3B1 mutations cause deleterious effects in many genes simultaneously, and altered 39 splice sites were found in genes involved in heme biosynthesis, cell cycle progression, and DNA repair and their consequence was mostly deleteriously due to aberrant frameshifts.
Journal ArticleDOI
Attenuated familial adenomatous polyposis with desmoids caused by an APC mutation.
Tsuneo Ikenoue,Kiyoshi Yamaguchi,Mitsuhiro Komura,Seiya Imoto,Rui Yamaguchi,Eigo Shimizu,Shinichi Kasuya,Tetsuo Shibuya,Seira Hatakeyama,Satoru Miyano,Yoichi Furukawa +10 more
TL;DR: In cases with limited numbers of colonic polyps and desmoids, AFAP may be caused by a mutation in the 3′ region of APC.
Journal Article
Biopathways representation and simulation on hybrid functional petri net.
TL;DR: A novel notion of Petri net is defined called Hybrid Functional Petri Net (HFPN) and a software tool, Genomic Object Net, is introduced for representing and simulating biopathways, which is developed by employing the architecture of HFPN.