S
Satoru Miyano
Researcher at Tokyo Medical and Dental University
Publications - 874
Citations - 45801
Satoru Miyano is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 84, co-authored 811 publications receiving 38723 citations. Previous affiliations of Satoru Miyano include University of Paderborn & Institute of Medical Science.
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A filter based feature selection algorithm using null space of covariance matrix for DNA microarray gene expression data
TL;DR: The algorithm can perform bulk reduction of features (genes) while maintaining the quality information in the reduced subset of features for discriminative purpose and can be used as a pre-processing step for other feature selection algorithms.
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Statistical analysis of hie (cold sensation) and hiesho (cold disorder) in kampo clinic.
Tetsuhiro Yoshino,Kotoe Katayama,Kaori Munakata,Yuko Horiba,Rui Yamaguchi,Seiya Imoto,Satoru Miyano,Kenji Watanabe +7 more
TL;DR: Analysis of data from new patients seen at the Kampo Clinic at Keio University Hospital between 2008 and 2013 found that men with hiesho had the same distribution of hie and had symptoms similar to women.
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Vasohibin-1 is identified as a master-regulator of endothelial cell apoptosis using gene network analysis
Muna Affara,Debbie Sanders,Hiromitsu Araki,Yoshinori Tamada,Benjamin J. Dunmore,Sally Humphreys,Seiya Imoto,Christopher J. Savoie,Satoru Miyano,Satoru Kuhara,David Jeffries,Cristin G. Print,D. Stephen Charnock-Jones,D. Stephen Charnock-Jones +13 more
TL;DR: This study demonstrates how GRN technology can complement traditional methods to hypothesise the regulatory relationships that underlie important biological processes as well as supporting an important biological role of VASH1 in EC.
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Somatic Mosaicism for a NRAS Mutation Associates with Disparate Clinical Features in RAS-associated Leukoproliferative Disease: a Report of Two Cases
Mitsutaka Shiota,Xi Yang,Xi Yang,Mei Kubokawa,Tatsuya Morishima,Kuniaki Tanaka,Masamitsu Mikami,Kenichi Yoshida,Masako Kikuchi,Kazushi Izawa,Ryuta Nishikomori,Yusuke Okuno,Xian Wang,Hirotoshi Sakaguchi,Hideki Muramatsu,Seiji Kojima,Satoru Miyano,Seishi Ogawa,Masatoshi Takagi,Daisuke Hata,Hirokazu Kanegane,Hirokazu Kanegane +21 more
TL;DR: Clinical and experimental data increase the understanding of RALD, ALPS, and JMML and suggest genetic analysis of RAS should be performed in patients fulfilling the diagnostic criteria for ALPS in the absence of ALPS-related gene mutations if the patients have elevated αβ-double-negative-T cells and in JMML patients if autoimmunity is detected.
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A female patient with incomplete hemophagocytic lymphohistiocytosis caused by a heterozygous XIAP mutation associated with non-random X-chromosome inactivation skewed towards the wild-type XIAP allele.
Xi Yang,Akihiro Hoshino,Takashi Taga,Tomoaki Kunitsu,Yuhachi Ikeda,Takahiro Yasumi,Kenichi Yoshida,Taizo Wada,Kunio Miyake,Takeo Kubota,Yusuke Okuno,Hideki Muramatsu,Yuichi Adachi,Satoru Miyano,Seishi Ogawa,Seiji Kojima,Hirokazu Kanegane,Hirokazu Kanegane +17 more
TL;DR: This is the first report of a female patient with incomplete HLH resulting from a heterozygous XIAP mutation in association with non-random XCI, and in the female patient, the paternally derived X chromosome was non- randomly and exclusively inactivated in her peripheral blood and hair root cells.