S
Satoru Miyano
Researcher at Tokyo Medical and Dental University
Publications - 874
Citations - 45801
Satoru Miyano is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 84, co-authored 811 publications receiving 38723 citations. Previous affiliations of Satoru Miyano include University of Paderborn & Institute of Medical Science.
Papers
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Proceedings ArticleDOI
A Structure Learning Algorithm for Inference of Gene Networks from Microarray Gene Expression Data Using Bayesian Networks
TL;DR: Bayesian networks is used as a mathematical model for reverse-engineering gene networks from microarray data by extending K2 algorithm that is one of the standard learning algorithms in Bayesian networks to develop more efficient algorithms to learn Bayesian network structure based on observed data.
Journal ArticleDOI
A simple greedy algorithm for finding functional relations: efficient implementation and average case analysis
TL;DR: An efficient implementation of a simple greedy algorithm for inferring functional relations from relational databases is presented and it is shown that the algorithm can identify an exact solution for simple functions if input data for each function are generated uniformly at random and the size of the domain is bounded by a constant.
Journal ArticleDOI
Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia.
Hidemasa Matsuo,Kenichi Yoshida,Kazutaka Fukumura,Kana Nakatani,Yuki Noguchi,Saho Takasaki,Mina Noura,Yusuke Shiozawa,Yuichi Shiraishi,Kenichi Chiba,Hiroko Tanaka,Ai Okada,Yasuhito Nannya,June Takeda,Hiroo Ueno,Norio Shiba,Genki Yamato,Hiroshi Handa,Yuichiro Ono,Nobuhiro Hiramoto,Takayuki Ishikawa,Kensuke Usuki,Ken Ishiyama,Shuichi Miyawaki,Hidehiro Itonaga,Yasushi Miyazaki,Machiko Kawamura,Hiroki Yamaguchi,Nobutaka Kiyokawa,Daisuke Tomizawa,Takashi Taga,Akio Tawa,Yasuhide Hayashi,Hiroyuki Mano,Satoru Miyano,Yasuhiko Kamikubo,Seishi Ogawa,Souichi Adachi +37 more
TL;DR: Pediatric MLL-MLLT3-rearranged AML patients with coexisting mutations had significantly reduced relapse-free survival and overall survival compared with those without co existing mutations (n = 9) (P = .048 and .046, respectively).
Proceedings ArticleDOI
Intrasplicing--analysis of long intron sequences.
TL;DR: A new computational method for the analysis of DNA sequences with respect to splicing is developed and several results are derived indicating that intrasplicing may be an appropriate model for the splicing of at least part of the long intron sequences.
Journal ArticleDOI
Reduced expression of APC-1B but not APC-1A by the deletion of promoter 1B is responsible for familial adenomatous polyposis
Kiyoshi Yamaguchi,Satoshi Nagayama,Eigo Shimizu,Mitsuhiro Komura,Rui Yamaguchi,Tetsuo Shibuya,Masami Arai,Seira Hatakeyama,Tsuneo Ikenoue,Masashi Ueno,Satoru Miyano,Seiya Imoto,Yoichi Furukawa +12 more
TL;DR: The results strengthen the evidence that analysis of structural variations in promoter 1B should be considered for the FAP patients whose pathological mutations are not identified by conventional direct sequencing.