S
Satoru Miyano
Researcher at Tokyo Medical and Dental University
Publications - 874
Citations - 45801
Satoru Miyano is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 84, co-authored 811 publications receiving 38723 citations. Previous affiliations of Satoru Miyano include University of Paderborn & Institute of Medical Science.
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Journal ArticleDOI
Tracing the development of acute myeloid leukemia in CBL syndrome
Heiko Becker,Kenichi Yoshida,Kenichi Yoshida,Nadja Blagitko-Dorfs,Rainer Claus,Milena Pantic,Mahmoud Abdelkarim,Christoph Niemöller,Christine Greil,Björn Hackanson,Yuichi Shiraishi,Kenichi Chiba,Hiroko Tanaka,Satoru Miyano,Konstanze Döhner,Susanne Schnittger,Philipp Henneke,Charlotte M. Niemeyer,Christian Flotho,Dietmar Pfeifer,Seishi Ogawa,Seishi Ogawa,Michael Lübbert +22 more
TL;DR: During complete remission of the AML, the hematopoiesis stably maintained the homozygous CBL mutation, which is reminiscent of the situation in children with CBL syndrome and transient juvenile myelomonocytic leukemia.
Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs
Asuka Nakata,Ryo Yoshida,Rui Yamaguchi,Yoshinori Tamada,André Fujita,Teppei Shimamura,Seiya Imoto,Tomoyuki Higuchi,Masaharu Nomura,Tatsuo Kimura,Hiroshi Nokihara,Masahiko Higashiyama,Kazuya Kondoh,Hiroshi Nishihara,Arinobu Tojo,Seiji Yano,Satoru Miyano,Noriko Gotoh +17 more
TL;DR: A rationale for combination therapy that includes targeting of the Akt-β-catenin pathway to improve the efficacy of EGFR-TKIs is provided.
Journal Article
Parallel Algorithms for Refutation Tree Problem on Formal Graph Systems
TL;DR: In this article, the authors define a new framework for rewriting graphs, called a formal graph system (FGS), which is a logic program having hypergraphs instead of terms in first-order logic.
Posted ContentDOI
Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments
Christina K. Yung,Brian O'Connor,Sergei Yakneen,Junjun Zhang,Kyle Ellrott,Kortine Kleinheinz,Miyoshi N,Raine Km,Romina Royo,Gordon Saksena,Matthias Schlesner,Solomon Shorser,Miguel Vazquez,Joachim Weischenfeldt,Denis Yuen,Adam Butler,Brandi N. Davis-Dusenbery,Roland Eils,Ferretti,Robert L. Grossman,Olivier Harismendy,Yong Ho Kim,Hidewaki Nakagawa,Steven Newhouse,David Torrents,Lincoln Stein,Rodriguez Jb,Keith A. Boroevich,Boyce R,Angela N. Brooks,Alex Buchanan,Ivo Buchhalter,Ivo Buchhalter,Byrne Nj,Andy Cafferkey,Peter J. Campbell,Zhao Chen,Sung-Hoon Cho,Choi W,Peter Clapham,De La Vega Fm,Jonas Demeulemeester,Jonas Demeulemeester,Michelle Dow,L. J. Dursi,Jürgen Eils,Claudiu Farcas,Francesco Favero,Fayzullaev N,Paul Flicek,Nuno A. Fonseca,Josep Lluís Gelpí,Josep Lluís Gelpí,Gad Getz,Gad Getz,Gibson B,Michael Heinold,Michael Heinold,Julian M. Hess,Oliver Hofmann,Hong Jh,Thomas J. Hudson,Daniel Huebschmann,Daniel Huebschmann,Barbara Hutter,Carolyn M. Hutter,Seiya Imoto,Ivkovic S,Jeon S,Wei Jiao,Jongsun Jung,Rolf Kabbe,André Kahles,Jules Kerssemakers,Kim H,Jae H. Kim,Jan O. Korbel,Koscher M,Koures A,Kovacevic M,Christian Lawerenz,Ignaty Leshchiner,Dimitri Livitz,Mihaiescu Gl,Mijalkovic S,Lazic Am,Satoru Miyano,Nahal Hk,Nastic M,Nicholson J,Ocana D,Ohi K,Lucila Ohno-Machado,Larsson Omberg,Francis Ouellette B,Nagarajan Paramasivam,Nagarajan Paramasivam,Perry,Perry,Todd Pihl,Manuel Prinz,Montserrat Puiggròs,Radovic P,Esther Rheinbay,Esther Rheinbay,Rosenberg Mw,Rosenberg Mw,Short C,Heidi J. Sofia,Jonathan Spring,Adam J Struck,Grace Tiao,Tijanic N,Peter Van Loo,Peter Van Loo,Vicente D,Jeremiah Wala,Jeremiah Wala,Zhining Wang,Johannes Werner,April E. Williams,Young-Choon Woo,Adam Wright,Qian Xiang +123 more
TL;DR: The International Cancer Genome Consortium’s Pan-Cancer Analysis of Whole Genomes (PCAWG) project aimed to categorize somatic and germline variations in both coding and non-coding regions in over 2,800 cancer patients to provide high-quality validated consensus variants for downstream analysis.
Journal ArticleDOI
Genetic basis of myeloid transformation in familial platelet disorder/acute myeloid leukemia patients with haploinsufficient RUNX1 allele
Masatoshi Sakurai,Hidenori Kasahara,Kenichi Yoshida,Akihide Yoshimi,Hiroyoshi Kunimoto,Naohide Watanabe,Yuichi Shiraishi,Kenichi Chiba,Hirotoshi Tanaka,Yuka Harada,Hironori Harada,T. Kawakita,Mineo Kurokawa,Satoru Miyano,Satoru Takahashi,Seishi Ogawa,Shinichiro Okamoto,Hideaki Nakajima +17 more
TL;DR: The genetic basis of myeloid transformation in familial platelet disorder/acute myeloids leukemia patients with haploinsufficient RUNX1 allele is studied.