Satoru Miyano

TL;DR: A new system consisting of interactome screening for the herpes simplex virus 1 (HSV-1) nuclear egress complex (NEC), followed by loss-of-function screening to target the identified putative NEC-interacting cellular proteins to detect a defect in HSV- 1nuclear egress identified SLC35E1, an orphan transporter, as a novel cellular protein required for efficient HSv-1 de-envelopment.

TL;DR: In this article, a machine learning system called HAKKE was developed for predicting functional regions from sequences, such as protein-coding region prediction, and transmembrane domain prediction.

TL;DR: Oral cyclosporin A administration resulted in prompt improvement of anemia, suggesting its high sensitivity, and whole-exome sequencing of his peripheral blood DNA revealed somatic mutations in 33 genes, including the STAT3 gene, implying their roles in T-LGL leukemia.

TL;DR: A new high throughput sequencing method to investigate the detailed genetic profiling of the TCR repertoire of millions of peripheral T lymphocytes from non-small cell lung cancer patients who had been treated with cancer vaccine cocktail of peptides derived from CDCA1, URLC10, and KIF20A and should contribute to the better understanding of the immune responses in patients treated with immunotherapy.

TL;DR: A simple scheme for assigning certainty-factor parameters with a given reasoning tree is presented, in which an input ux is divided into thinner ows on a step-by-step basis according to some characteristic values calculated from the input sequence.