Satoru Miyano

TL;DR: This work has succeeded in finding rules whose prediction accuracies come close to that of TargetP, while still retaining a very simple and interpretable form.

TL;DR: In this article, the authors delineate the entire picture of genetic alterations and affected pathways in these glioma types, with sensitive detection of driver genes Grade II and III gliomas comprise three distinct subtypes characterized by discrete sets of mutations and distinct clinical behaviors, suggesting that there is functional interplay between the mutations that drive clonal selection.

TL;DR: An extensive genome-wide expression profiling of 226 primary human stage I-II lung adenocarcinomas helps identify patients who may gain the most benefit from adjuvant chemotherapy after surgical resection and further stratify more or less aggressive subgroups of triple-negative lung ADC.

TL;DR: The identified alterations overlap significantly with the HTLV-1 Tax interactome and are highly enriched for T cell receptor–NF-κB signaling, T cell trafficking and other T cell–related pathways as well as immunosurveillance.

TL;DR: In this article, a comprehensive analysis identified point mutations, structural variations (STVs), and virus integrations, in noncoding and coding regions of 300 liver cancers from Japanese individuals.