S
Satoru Miyano
Researcher at Tokyo Medical and Dental University
Publications - 874
Citations - 45801
Satoru Miyano is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 84, co-authored 811 publications receiving 38723 citations. Previous affiliations of Satoru Miyano include University of Paderborn & Institute of Medical Science.
Papers
More filters
Journal ArticleDOI
Landscape and function of multiple mutations within individual oncogenes
Yuki Saito,Junji Koya,Mitsugu Araki,Yasunori Kogure,Sumito Shingaki,Mariko Tabata,Marni B McClure,Kota Yoshifuji,Shigeyuki Matsumoto,Yuta Isaka,Hiroko Tanaka,Takanori Kanai,Satoru Miyano,Yuichi Shiraishi,Yasushi Okuno,Keisuke Kataoka +15 more
TL;DR: Oncogenic MMs are a relatively common driver event, providing the underlying mechanism for clonal selection of suboptimal mutations that are individually rare but collectively account for a substantial proportion of oncogenic mutations.
Journal ArticleDOI
Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain
Kazuhiko Tagawa,Hidenori Homma,Ayumu Saito,Kyota Fujita,Xigui Chen,Seiya Imoto,Tsutomu Oka,Hikaru Ito,Kazumi Motoki,Chisato Yoshida,Hiroyuki Hatsuta,Shigeo Murayama,Takeshi Iwatsubo,Satoru Miyano,Hitoshi Okazawa +14 more
TL;DR: Two-photon microscopic observation revealed recovery of abnormal spine formation in the AD model mice by targeting a core protein MARCKS or by inhibiting candidate kinases, supporting the hypothesis formulated based on phosphoproteome analysis.
Journal ArticleDOI
Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
Takashi Takei,Aritoshi Iida,Kosaku Nitta,Toshihiro Tanaka,Yozo Ohnishi,Ryo Yamada,Shiro Maeda,Tatsuhiko Tsunoda,Sachiyo Takeoka,Kyoko Ito,Kazuho Honda,Keiko Uchida,Ken Tsuchiya,Yasushi Suzuki,Tomoaki Fujioka,Takashi Ujiie,Yutaka Nagane,Satoru Miyano,Ichiei Narita,Fumitake Gejyo,Hiroshi Nihei,Yusuke Nakamura +21 more
TL;DR: The results suggest that these eight SNPs in selectin genes may be useful for screening populations susceptible to the IgAN phenotype that involves interstitial infiltration.
Journal ArticleDOI
Gene network inference and visualization tools for biologists: application to new human transcriptome datasets.
Daniel G. Hurley,Hiromitsu Araki,Yoshinori Tamada,Ben Dunmore,Deborah A. Sanders,Sally Humphreys,Muna Affara,Seiya Imoto,Kaori Yasuda,Yuki Tomiyasu,Kosuke Tashiro,Christopher J. Savoie,Vicky Cho,Stephen Smith,Satoru Kuhara,Satoru Miyano,D. Stephen Charnock-Jones,Edmund J. Crampin,Cristin G. Print +18 more
TL;DR: A suite of tools for analysing regulatory networks is assembled, and their use with microarray datasets generated in human endothelial cells is illustrated.
Journal ArticleDOI
Null space based feature selection method for gene expression data
TL;DR: A null space based feature selection method for gene expression data in terms of supervised classification that discards the redundant genes by applying the information of null space of scatter matrices is proposed.