S
Satoru Miyano
Researcher at Tokyo Medical and Dental University
Publications - 874
Citations - 45801
Satoru Miyano is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 84, co-authored 811 publications receiving 38723 citations. Previous affiliations of Satoru Miyano include University of Paderborn & Institute of Medical Science.
Papers
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Journal ArticleDOI
Identifying regulational alterations in gene regulatory networks by state space representation of vector autoregressive models and variational annealing
Kaname Kojima,Seiya Imoto,Rui Yamaguchi,André Fujita,Mai Yamauchi,Noriko Gotoh,Satoru Miyano +6 more
TL;DR: A new statistical approach is proposed that is based on the state space representation of the vector autoregressive model and estimates gene networks on two different conditions in order to identify changes on regulations between the conditions and can identifyChanges on regulations more accurately than existing methods.
Journal ArticleDOI
The landscape of genetic aberrations in myxofibrosarcoma
Yasuhide Takeuchi,Kenichi Yoshida,Adriane Halik,Annegret Kunitz,Hiromichi Suzuki,Nobuyuki Kakiuchi,Yusuke Shiozawa,Akira Yokoyama,Yoshikage Inoue,Tomonori Hirano,Tetsuichi Yoshizato,Kosuke Aoki,Yoichi Fujii,Yasuhito Nannya,Hideki Makishima,Berit M. Pfitzner,Lars Bullinger,Masahiro Hirata,Keita Jinnouchi,Yuichi Shiraishi,Kenichi Chiba,Hiroko Tanaka,Satoru Miyano,Takashi Okamoto,Hironori Haga,Seishi Ogawa,Frederik Damm +26 more
TL;DR: Longitudinal analysis of paired diagnosis and relapse time points revealed a 1.2‐fold mutation number increase accompanied with substantial changes in clonal composition over time, highlighting the genetic complexity underlying sarcomagenesis of MFS.
Journal ArticleDOI
Paraneoplastic hypereosinophilic syndrome associated with IL3‐IgH positive acute lymphoblastic leukemia
Kenichiro Kobayashi,Shumpei Mizuta,Noriko Yamane,Hiroo Ueno,Kenichi Yoshida,Itaru Kato,Katsutsugu Umeda,Hidefumi Hiramatsu,Minoru Suehiro,Toshiro Maihara,Ikuya Usami,Yuichi Shiraishi,Kenichi Chiba,Satoru Miyano,Souichi Adachi,Seishi Ogawa,Seishi Ogawa,Nobutaka Kiyokawa,Toshio Heike +18 more
TL;DR: An 11-year-old male with ALL with hypereosinophilia was encountered and three-drug therapy with prednisolone, vincristine, and Lasparaginase was successful with an induction of morphological remission, and headto-head gene fusion between the immunoglobulin heavy-chain joining enhancer and IL3 promoter region was confirmed.
Patent
Estimating gene networks using inferential methods and biological constraints
Sascha Ott,Satoru Miyano +1 more
TL;DR: In this article, a general approach to reduce the search space to a biologically meaningful subspace and to find optimal solutions within the subspace in linear time by using inferential models constrained by biologically relevant information is presented.
Journal ArticleDOI
ExonMiner: Web service for analysis of GeneChip Exon array data
TL;DR: ExonMiner is the first all-in-one web service for analysis of exon array data to detect transcripts that have significantly different splicing patterns in two cells, e.g. normal and cancer cells, and has the potential to reveal the aberrant splice variations in cancer cells as exon level biomarkers.