T
Timothy C. Barnett
Researcher at University of Queensland
Publications - 41
Citations - 3751
Timothy C. Barnett is an academic researcher from University of Queensland. The author has contributed to research in topics: Streptococcus pyogenes & Innate immune system. The author has an hindex of 24, co-authored 41 publications receiving 3173 citations. Previous affiliations of Timothy C. Barnett include Telethon Institute for Child Health Research & University of Western Australia.
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Journal ArticleDOI
Pathogenesis of group A streptococcal infections.
TL;DR: A vaccine capable of preventing GAS infection may be the only effective way to control and eliminate G AS infection and disease.
Journal ArticleDOI
Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus
Mark J. Walker,Timothy C. Barnett,Jason D. McArthur,Jason N. Cole,Jason N. Cole,Christine M. Gillen,Anna Henningham,Anna Henningham,Kadaba S. Sriprakash,Martina L. Sanderson-Smith,Victor Nizet,Victor Nizet +11 more
TL;DR: Genomic and molecular analyses have now characterized a large number of GAS virulence determinants, many of which exhibit overlap and redundancy in the processes of adhesion and colonization, innate immune resistance, and the capacity to facilitate tissue barrier degradation and spread within the human host.
Journal ArticleDOI
Molecular insight into invasive group A streptococcal disease
TL;DR: The virulence factors and newly discovered molecular events that mediate the in vivo changes from non-invasive GAS serotype M1T1 to the invasive phenotype are described and the invasive-disease trigger for non-M1 GAS is reviewed.
Journal ArticleDOI
Surface Proteins of Gram-Positive Bacteria and How They Get There
June R. Scott,Timothy C. Barnett +1 more
TL;DR: The structure of the cell surface is the major characteristic that distinguishes gram-positive from gram-negative bacteria, and the processes used to transport and attach these proteins show significant differences between these bacterial classes.
Journal ArticleDOI
FANTOM5 CAGE profiles of human and mouse samples
Shuhei Noguchi,Takahiro Arakawa,Shiro Fukuda,Masaaki Furuno,Akira Hasegawa,Fumi Hori,Sachi Ishikawa-Kato,Kaoru Kaida,Ai Kaiho,Mutsumi Kanamori-Katayama,Tsugumi Kawashima,Miki Kojima,Atsutaka Kubosaki,Ri Ichiroh Manabe,Mitsuyoshi Murata,Sayaka Nagao-Sato,Kenichi Nakazato,Noriko Ninomiya,Hiromi Nishiyori-Sueki,Shohei Noma,Eri Saijyo,Akiko Saka,Mizuho Sakai,Christophe Simon,Naoko Suzuki,Michihira Tagami,Shoko Watanabe,Shigehiro Yoshida,Peter Arner,Richard A Axton,Magda Babina,J Kenneth Baillie,Timothy C. Barnett,Anthony G Beckhouse,Antje Blumenthal,Beatrice Bodega,Alessandro Bonetti,James Briggs,Frank Brombacher,Frank Brombacher,Ailsa J Carlisle,Hans Clevers,Hans Clevers,Carrie A. Davis,Michael Detmar,Taeko Dohi,B. Albert S. Edge,Matthias Edinger,Anna Ehrlund,Karl Ekwall,Mitsuhiro Endoh,Hideki Enomoto,Afsaneh Eslami,Michela Fagiolini,Lynsey Fairbairn,Mary C. Farach-Carson,Geoffrey J. Faulkner,Carmelo Ferrai,Malcolm E. Fisher,Lesley M. Forrester,Rie Fujita,Jun Ichi Furusawa,Teunis B. H. Geijtenbeek,Thomas R. Gingeras,Dan Goldowitz,Sven Guhl,Reto Guler,Reto Guler,Stefano Gustincich,Stefano Gustincich,Thomas J. Ha,Masahide Hamaguchi,Mitsuko Hara,Yuki Hasegawa,Meenhard Herlyn,Peter Heutink,Kelly J Hitchens,David A. Hume,Tomokatsu Ikawa,Yuri Ishizu,Chieko Kai,Hiroshi Kawamoto,Yuki I. Kawamura,Judith S. Kempfle,Tony J. Kenna,Juha Kere,Juha Kere,Levon M. Khachigian,Toshio Kitamura,Sarah Klein,S. Peter Klinken,Alan J. Knox,Soichi Kojima,Haruhiko Koseki,Shigeo Koyasu,Weon Ju Lee,Andreas Lennartsson,Alan Mackay-Sim,Niklas Mejhert,Yosuke Mizuno,Hiromasa Morikawa,Mitsuru Morimoto,Kazuyo Moro,Kelly J. Morris,Hozumi Motohashi,Christine L. Mummery,Yutaka Nakachi,Yutaka Nakachi,Fumio Nakahara,Toshiyuki Nakamura,Yukio Nakamura,Tadasuke Nozaki,Soichi Ogishima,Naganari Ohkura,Hiroshi Ohno,Mitsuhiro Ohshima,Mariko Okada-Hatakeyama,Yasushi Okazaki,Valerio Orlando,Dmitry A. Ovchinnikov,Robert Passier,Margaret Patrikakis,Ana Pombo,Swati Pradhan-Bhatt,Xian-Yang Qin,Michael Rehli,Patrizia Rizzu,Sugata Roy,Antti Sajantila,Shimon Sakaguchi,Hiroki Sato,Hironori Satoh,Suzana Savvi,Suzana Savvi,Alka Saxena,Christian Schmidl,Claudio Schneider,Gundula Schulze-Tanzil,Anita Schwegmann,Anita Schwegmann,Guojun Sheng,Jay W. Shin,Daisuke Sugiyama,Takaaki Sugiyama,Kim M. Summers,Naoko Takahashi,Jun Takai,Hiroshi Tanaka,Hideki Tatsukawa,Andru Tomoiu,Hiroo Toyoda,Marcvande Wetering,Linda M. van den Berg,Roberto Verardo,Dipti Vijayan,Christine A. Wells,Louise N. Winteringham,Ernst J. Wolvetang,Yoko Yamaguchi,Masayuki Yamamoto,Chiyo Yanagi-Mizuochi,Misako Yoneda,Yohei Yonekura,Peter G. Zhang,Silvia Zucchelli,Imad Abugessaisa,Erik Arner,Jayson Harshbarger,Atsushi Kondo,Timo Lassmann,Marina Lizio,Serkan Sahin,Thierry Sengstag,Jessica Severin,Hisashi Shimoji,Masanori Suzuki,Harukazu Suzuki,Jun Kawai,Naoto Kondo,Masayoshi Itoh,Carsten O. Daub,Takeya Kasukawa,Hideya Kawaji,Piero Carninci,Alistair R. R. Forrest,Yoshihide Hayashizaki +185 more
TL;DR: In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE coupled with single-molecule sequencing to represent the consequence of transcriptional regulation in each analyzed state of mammalian cells.