H
Hiroshi Tanaka
Researcher at Tokyo Medical and Dental University
Publications - 223
Citations - 5930
Hiroshi Tanaka is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Rough set & Cancer. The author has an hindex of 33, co-authored 222 publications receiving 5312 citations. Previous affiliations of Hiroshi Tanaka include Hyogo College of Medicine & Tohoku University.
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Journal ArticleDOI
A promoter-level mammalian expression atlas
Alistair R. R. Forrest,Hideya Kawaji,Michael Rehli,J Kenneth Baillie,Michiel J. L. de Hoon,Vanja Haberle,Vanja Haberle,Timo Lassmann,Ivan V. Kulakovskiy,Ivan V. Kulakovskiy,Marina Lizio,Masayoshi Itoh,Robin Andersson,Christopher J. Mungall,Terrence F. Meehan,Sebastian Schmeier,Sebastian Schmeier,Nicolas Bertin,Mette C. Jørgensen,Emmanuel Dimont,Erik Arner,Christian Schmidl,Christian Schmidl,Ulf Schaefer,Yulia A. Medvedeva,Yulia A. Medvedeva,Charles Plessy,Morana Vitezic,Jessica Severin,Colin A. Semple,Yuri Ishizu,Robert Young,Margherita Francescatto,Margherita Francescatto,Intikhab Alam Altschuler,Davide Albanese,Gabriel M. Altschule,Takahiro Arakawa,John A.C. Archer,Peter Arner,Magda Babina,Sarah Rennie,Piotr J. Balwierz,Anthony G Beckhouse,Swati Pradhan-Bhatt,Judith A. Blake,Antje Blumenthal,Beatrice Bodega,Alessandro Bonetti,James Briggs,James Briggs,Frank Brombacher,Frank Brombacher,A. Maxwell Burroughs,Andrea Califano,Carlo Vittorio Cannistraci,Carlo Vittorio Cannistraci,Daniel Carbajo,Yun Chen,Marco Chierici,Yari Ciani,Hans Clevers,Hans Clevers,Emiliano Dalla,Carrie A. Davis,Michael Detmar,Alexander D. Diehl,Taeko Dohi,Finn Drabløs,Albert S.B. Edge,Matthias Edinger,Karl Ekwall,Mitsuhiro Endoh,Hideki Enomoto,Michela Fagiolini,Lynsey Fairbairn,Hai Fang,Mary C. Farach-Carson,Geoffrey J. Faulkner,Alexander V. Favorov,Alexander V. Favorov,Alexander V. Favorov,Malcolm E. Fisher,Martin C. Frith,Rie Fujita,Shiro Fukuda,Cesare Furlanello,Masaaki Furuno,Jun Ichi Furusawa,Teunis B. H. Geijtenbeek,Andrew P. Gibson,Thomas R. Gingeras,Dan Goldowitz,Julian Gough,Sven Guhl,Reto Guler,Reto Guler,Stefano Gustincich,Thomas J. Ha,Masahide Hamaguchi,Mitsuko Hara,Matthias Harbers,Jayson Harshbarger,Akira Hasegawa,Yuki Hasegawa,Takehiro Hashimoto,Meenhard Herlyn,Kelly J Hitchens,Shannan J. Ho Sui,Oliver Hofmann,Ilka Hoof,Fumi Hori,Lukasz Huminiecki,Kei Iida,Tomokatsu Ikawa,Boris R. Jankovic,Hui Jia,Anagha Joshi,Giuseppe Jurman,Bogumil Kaczkowski,Chieko Kai,Kaoru Kaida,Ai Kaiho,Kazuhiro Kajiyama,Mutsumi Kanamori-Katayama,Artem S. Kasianov,Takeya Kasukawa,Shintaro Katayama,Sachi Kato,Shuji Kawaguchi,Hiroshi Kawamoto,Yuki I. Kawamura,Tsugumi Kawashima,Judith S. Kempfle,Tony J. Kenna,Juha Kere,Juha Kere,Levon M. Khachigian,Toshio Kitamura,S. Peter Klinken,Alan J. Knox,Miki Kojima,Soichi Kojima,Naoto Kondo,Haruhiko Koseki,Shigeo Koyasu,Sarah Krampitz,Atsutaka Kubosaki,Andrew T. Kwon,Jeroen F. J. Laros,Weon Ju Lee,Andreas Lennartsson,Kang Li,Berit Lilje,Leonard Lipovich,Alan Mackay-Sim,Ri Ichiroh Manabe,Jessica C. Mar,Benoit Marchand,Anthony Mathelier,Niklas Mejhert,Alison M. Meynert,Yosuke Mizuno,David A. de Lima Morais,Hiromasa Morikawa,Mitsuru Morimoto,Kazuyo Moro,Efthymios Motakis,Hozumi Motohashi,Christine L. Mummery,Mitsuyoshi Murata,Sayaka Nagao-Sato,Yutaka Nakachi,Fumio Nakahara,Toshiyuki Nakamura,Yukio Nakamura,Kenichi Nakazato,Erik van Nimwegen,Noriko Ninomiya,Hiromi Nishiyori,Shohei Noma,Tadasuke Nozaki,Soichi Ogishima,Soichi Ogishima,Naganari Ohkura,Hiroko Ohmiya,Hiroshi Ohno,Mitsuhiro Ohshima,Mariko Okada-Hatakeyama,Yasushi Okazaki,Valerio Orlando,Dmitry A. Ovchinnikov,Arnab Pain,Robert Passier,Margaret Patrikakis,Helena Persson,Silvano Piazza,James Prendergast,Owen J. L. Rackham,Jordan A. Ramilowski,Mamoon Rashid,Timothy Ravasi,Patrizia Rizzu,Marco Roncador,Sugata Roy,Morten Beck Rye,Eri Saijyo,Antti Sajantila,Akiko Saka,Shimon Sakaguchi,Mizuho Sakai,Hiroki Sato,Hironori Satoh,Suzana Savvi,Suzana Savvi,Alka Saxena,Claudio Schneider,Erik Anthony Schultes,Gundula G. Schulze-Tanzil,Anita Schwegmann,Anita Schwegmann,Thierry Sengstag,Guojun Sheng,Hisashi Shimoji,Yishai Shimoni,Jay W. Shin,Christophe Simon,Daisuke Sugiyama,Takaaki Sugiyama,Masanori Suzuki,Naoko Suzuki,Rolf Swoboda,Peter A C 't Hoen,Michihira Tagami,Naoko Takahashi Tagami,Jun Takai,Hiroshi Tanaka,Hideki Tatsukawa,Zuotian Tatum,Mark Thompson,Hiroo Toyoda,Tetsuro Toyoda,Eivind Valen,Marc van de Wetering,Linda M. van den Berg,Roberto Verardo,Dipti Vijayan,Ilya E. Vorontsov,Wyeth W. Wasserman,Shoko Watanabe,Christine A. Wells,Louise N. Winteringham,Ernst J. Wolvetang,Emily J. Wood,Yoko Yamaguchi,Masayuki Yamamoto,Misako Yoneda,Yohei Yonekura,Shigehiro Yoshida,Susan E. Zabierowski,Peter G. Zhang,Xiaobei Zhao,Silvia Zucchelli,Kim M. Summers,Harukazu Suzuki,Carsten O. Daub,Jun Kawai,Peter Heutink,Winston Hide,Tom C. Freeman,Boris Lenhard,Boris Lenhard,Lenhard Vladimir B. Bajic,Martin S. Taylor,Vsevolod J. Makeev,Vsevolod J. Makeev,Vsevolod J. Makeev,Albin Sandelin,David A. Hume,Piero Carninci,Yoshihide Hayashizaki +280 more
TL;DR: For example, the authors mapped transcription start sites (TSSs) and their usage in human and mouse primary cells, cell lines and tissues to produce a comprehensive overview of mammalian gene expression across the human body.
Journal ArticleDOI
Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones
Tadashi Imanishi,Takeshi Itoh,Yutaka Suzuki,Claire O'Donovan,Satoshi Fukuchi,Kanako O. Koyanagi,Roberto A. Barrero,Takuro Tamura,Yumi Yamaguchi-Kabata,Motohiko Tanino,Kei Yura,Satoru Miyazaki,Kazuho Ikeo,Keiichi Homma,Arek Kasprzyk,Tetsuo Nishikawa,Mika Hirakawa,Jean Thierry-Mieg,Jean Thierry-Mieg,Danielle Thierry-Mieg,Danielle Thierry-Mieg,Jennifer L. Ashurst,Libin Jia,Mitsuteru Nakao,Michael A. Thomas,Nicola Mulder,Youla Karavidopoulou,Lihua Jin,Sangsoo Kim,Tomohiro Yasuda,Boris Lenhard,Eric Eveno,Yoshiyuki Suzuki,Chisato Yamasaki,Jun-ichi Takeda,Craig A. Gough,Phillip Hilton,Yasuyuki Fujii,Hiroaki Sakai,Susumu Tanaka,Clara Amid,Matthew I. Bellgard,Maria de Fatima Bonaldo,Hidemasa Bono,Susan Bromberg,Anthony J. Brookes,Elspeth A. Bruford,Piero Carninci,Claude Chelala,Christine Couillault,Sandro J. de Souza,Marie-Anne Debily,Marie-Dominique Devignes,Inna Dubchak,Toshinori Endo,Anne Estreicher,Eduardo Eyras,Kaoru Fukami-Kobayashi,Gopal R. Gopinath,Esther Graudens,Yoonsoo Hahn,Michael Han,Ze-Guang Han,Kousuke Hanada,Hideki Hanaoka,Erimi Harada,Katsuyuki Hashimoto,Ursula Hinz,Momoki Hirai,Teruyoshi Hishiki,Ian Hopkinson,Sandrine Imbeaud,Hidetoshi Inoko,Hidetoshi Inoko,Alexander Kanapin,Yayoi Kaneko,Takeya Kasukawa,Janet Kelso,Paul J. Kersey,Reiko Kikuno,Kouichi Kimura,Bernhard Korn,Vladimir Kuryshev,Izabela Makalowska,Takashi Makino,Shuhei Mano,Régine Mariage-Samson,Jun Mashima,Hideo Matsuda,Hans-Werner Mewes,Shinsei Minoshima,Shinsei Minoshima,Keiichi Nagai,Hideki Nagasaki,Naoki Nagata,Rajni Nigam,Osamu Ogasawara,Osamu Ohara,Masafumi Ohtsubo,Norihiro Okada,Toshihisa Okido,Satoshi Oota,Motonori Ota,Toshio Ota,Tetsuji Otsuki,Dominique Piatier-Tonneau,Annemarie Poustka,Shuang-Xi Ren,Naruya Saitou,Katsunaga Sakai,Shigetaka Sakamoto,Ryuichi Sakate,Ingo Schupp,Florence Servant,Stephen T. Sherry,Rie Shiba,Nobuyoshi Shimizu,Mary Shimoyama,Andrew J. G. Simpson,Bento Soares,Charles A. Steward,Makiko Suwa,Mami Suzuki,Aiko Takahashi,Gen Tamiya,Gen Tamiya,Hiroshi Tanaka,Todd D. Taylor,Joseph D. Terwilliger,Per Unneberg,Vamsi Veeramachaneni,Shinya Watanabe,Laurens G. Wilming,Norikazu Yasuda,Hyang-Sook Yoo,Marvin Stodolsky,Wojciech Makalowski,Mitiko Go,Kenta Nakai,Toshihisa Takagi,Minoru Kanehisa,Yoshiyuki Sakaki,John Quackenbush,Yasushi Okazaki,Yoshihide Hayashizaki,Winston Hide,Ranajit Chakraborty,Ken Nishikawa,Hideaki Sugawara,Yoshio Tateno,Zhu Chen,Zhu Chen,Michio Oishi,Peter J. Tonellato,Rolf Apweiler,Kousaku Okubo,Kousaku Okubo,Lukas Wagner,Stefan Wiemann,Robert L. Strausberg,Takao Isogai,Charles Auffray,Nobuo Nomura,Takashi Gojobori,Takashi Gojobori,Takashi Gojobori,Sumio Sugano,Sumio Sugano +167 more
TL;DR: The H-InvDB as discussed by the authors is a database of 41,118 full-length cDNAs that capture the gene transcripts as complete functional cassettes, providing an unequivocal report of structural and functional diversity at the gene level.
Journal ArticleDOI
Nuclear Receptor-Mediated Transcriptional Regulation in Phase I, II, and III Xenobiotic Metabolizing Systems
Kotoko Nakata,Yoshitomo Tanaka,Tatsuya Nakano,Tatsuhiko Adachi,Hiroshi Tanaka,Tsuguchika Kaminuma,Toshihisa Ishikawa +6 more
TL;DR: The role of NRs was comprehensively drawn up in cholesterol and bile acid homeostasis in human hepatocyte and elucidate nuclear receptor mediated xenobiotic processing loops and direct future research.
Journal ArticleDOI
FANTOM5 CAGE profiles of human and mouse samples
Shuhei Noguchi,Takahiro Arakawa,Shiro Fukuda,Masaaki Furuno,Akira Hasegawa,Fumi Hori,Sachi Ishikawa-Kato,Kaoru Kaida,Ai Kaiho,Mutsumi Kanamori-Katayama,Tsugumi Kawashima,Miki Kojima,Atsutaka Kubosaki,Ri Ichiroh Manabe,Mitsuyoshi Murata,Sayaka Nagao-Sato,Kenichi Nakazato,Noriko Ninomiya,Hiromi Nishiyori-Sueki,Shohei Noma,Eri Saijyo,Akiko Saka,Mizuho Sakai,Christophe Simon,Naoko Suzuki,Michihira Tagami,Shoko Watanabe,Shigehiro Yoshida,Peter Arner,Richard A Axton,Magda Babina,J Kenneth Baillie,Timothy C. Barnett,Anthony G Beckhouse,Antje Blumenthal,Beatrice Bodega,Alessandro Bonetti,James Briggs,Frank Brombacher,Frank Brombacher,Ailsa J Carlisle,Hans Clevers,Hans Clevers,Carrie A. Davis,Michael Detmar,Taeko Dohi,B. Albert S. Edge,Matthias Edinger,Anna Ehrlund,Karl Ekwall,Mitsuhiro Endoh,Hideki Enomoto,Afsaneh Eslami,Michela Fagiolini,Lynsey Fairbairn,Mary C. Farach-Carson,Geoffrey J. Faulkner,Carmelo Ferrai,Malcolm E. Fisher,Lesley M. Forrester,Rie Fujita,Jun Ichi Furusawa,Teunis B. H. Geijtenbeek,Thomas R. Gingeras,Dan Goldowitz,Sven Guhl,Reto Guler,Reto Guler,Stefano Gustincich,Stefano Gustincich,Thomas J. Ha,Masahide Hamaguchi,Mitsuko Hara,Yuki Hasegawa,Meenhard Herlyn,Peter Heutink,Kelly J Hitchens,David A. Hume,Tomokatsu Ikawa,Yuri Ishizu,Chieko Kai,Hiroshi Kawamoto,Yuki I. Kawamura,Judith S. Kempfle,Tony J. Kenna,Juha Kere,Juha Kere,Levon M. Khachigian,Toshio Kitamura,Sarah Klein,S. Peter Klinken,Alan J. Knox,Soichi Kojima,Haruhiko Koseki,Shigeo Koyasu,Weon Ju Lee,Andreas Lennartsson,Alan Mackay-Sim,Niklas Mejhert,Yosuke Mizuno,Hiromasa Morikawa,Mitsuru Morimoto,Kazuyo Moro,Kelly J. Morris,Hozumi Motohashi,Christine L. Mummery,Yutaka Nakachi,Yutaka Nakachi,Fumio Nakahara,Toshiyuki Nakamura,Yukio Nakamura,Tadasuke Nozaki,Soichi Ogishima,Naganari Ohkura,Hiroshi Ohno,Mitsuhiro Ohshima,Mariko Okada-Hatakeyama,Yasushi Okazaki,Valerio Orlando,Dmitry A. Ovchinnikov,Robert Passier,Margaret Patrikakis,Ana Pombo,Swati Pradhan-Bhatt,Xian-Yang Qin,Michael Rehli,Patrizia Rizzu,Sugata Roy,Antti Sajantila,Shimon Sakaguchi,Hiroki Sato,Hironori Satoh,Suzana Savvi,Suzana Savvi,Alka Saxena,Christian Schmidl,Claudio Schneider,Gundula Schulze-Tanzil,Anita Schwegmann,Anita Schwegmann,Guojun Sheng,Jay W. Shin,Daisuke Sugiyama,Takaaki Sugiyama,Kim M. Summers,Naoko Takahashi,Jun Takai,Hiroshi Tanaka,Hideki Tatsukawa,Andru Tomoiu,Hiroo Toyoda,Marcvande Wetering,Linda M. van den Berg,Roberto Verardo,Dipti Vijayan,Christine A. Wells,Louise N. Winteringham,Ernst J. Wolvetang,Yoko Yamaguchi,Masayuki Yamamoto,Chiyo Yanagi-Mizuochi,Misako Yoneda,Yohei Yonekura,Peter G. Zhang,Silvia Zucchelli,Imad Abugessaisa,Erik Arner,Jayson Harshbarger,Atsushi Kondo,Timo Lassmann,Marina Lizio,Serkan Sahin,Thierry Sengstag,Jessica Severin,Hisashi Shimoji,Masanori Suzuki,Harukazu Suzuki,Jun Kawai,Naoto Kondo,Masayoshi Itoh,Carsten O. Daub,Takeya Kasukawa,Hideya Kawaji,Piero Carninci,Alistair R. R. Forrest,Yoshihide Hayashizaki +185 more
TL;DR: In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE coupled with single-molecule sequencing to represent the consequence of transcriptional regulation in each analyzed state of mammalian cells.
Journal ArticleDOI
An empirical examination of the utility of codon-substitution models in phylogeny reconstruction.
TL;DR: Although computational burden makes codon models unfeasible for tree search in large data sets, it is suggested that they may be useful for comparing candidate trees and caution against use of overly complex substitution models.