Y
Yves Pommier
Researcher at National Institutes of Health
Publications - 847
Citations - 65543
Yves Pommier is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Topoisomerase & DNA. The author has an hindex of 123, co-authored 789 publications receiving 58898 citations. Previous affiliations of Yves Pommier include Purdue University & Kyushu University.
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Lasonolide compounds as reagents for inducing premature chromosome condensation and methods for treating disorders
TL;DR: In this article, a method for inducing premature chromosome condensation using lasonolide derivatives, and methods of treating disorders such as cancer, in a subject, the method comprising administering to the subject a lasonoline derivative, was described.
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Glutamine protects mouse spermatogonial stem cells against NOX1-derived ROS for sustaining self-renewal division in vitro.
Takehiro Miyazaki,Mito Kanatsu-Shinohara,Narumi Ogonuki,Shogo Matoba,Atsuo Ogura,Chihiro Yabe-Nishimura,Hongliang Zhang,Yves Pommier,Andreas Trumpp,Takashi Shinohara +9 more
TL;DR: In this paper , the role of Gln in ROS protection was demonstrated using cultured SSCs derived from immature testes, where Gln induced Myc expression to drive SSC self-renewal in vitro, whereas Gln deprivation triggered Trp53dependent apoptosis and impaired SSC activity.
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CellMinerCDB: NCATS is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations.
William C. Reinhold,Kelli M. Wilson,Fathi Elloumi,Katie Bradwell,Michele Ceribelli,Sudhir Varma,Yang-Hsin Wang,Damien Y. Duveau,Nikhil. S. Menon,Jane B. Trepel,Xiaohu Zhang,Carleen Klumpp-Thomas,Sam Michael,Paul Shinn,Augustin Luna,Craig J. Thomas,Yves Pommier +16 more
TL;DR: The CellMinerCDB:NCATS (https://discover.nci.nih.gov/rsconnect/cellminercdb_ncats/), which makes available activity information for 2,675 drugs and compounds, including multiple non-oncology drugs and 1,866 compounds unique to the National Center for Advancing Translational Sciences (NCATS), is presented in this article .
Journal ArticleDOI
Patient-Derived Organoids and Their Potential for Precision Medicine in Neuroendocrine Tumors
Cortez Briana N,Suresh Kumar,Yasuhiro Arakawa,D. Varghese,Rosandra N. Kaplan,Karlyne M. Reilly,Brigitte C. Widemann,Jonathan M. Hernandez,Craig Thomas,Yves Pommier,Nitin Roper,Rivero Jaydira Del +11 more
Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and
TL;DR: Analysis of microDNAs from a set of human cancer cell lines revealed lineage-specific patterns of microDNA origins and revealed that homologous recombination and non-homologous end joining repair pathways are not required for microDNA production.