Institution
Banaras Hindu University
Education•Varanasi, Uttar Pradesh, India•
About: Banaras Hindu University is a education organization based out in Varanasi, Uttar Pradesh, India. It is known for research contribution in the topics: Population & Catalysis. The organization has 11858 authors who have published 23917 publications receiving 464677 citations. The organization is also known as: Kashi Hindu Vishvavidyalay & Benares Hindu University.
Topics: Population, Catalysis, Dielectric, Alloy, Raman spectroscopy
Papers published on a yearly basis
Papers
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TL;DR: The gut microbiota is essential to health and has recently become a target for live bacterial cell biotherapies for various chronic diseases including metabolic syndrome, diabetes, obesity and neurodegenerative disease, where the management of the gut microbiota may prevent or alleviate the symptoms of these chronic diseases.
Abstract: The gut microbiota is essential to health and has recently become a target for live bacterial cell biotherapies for various chronic diseases including metabolic syndrome, diabetes, obesity and neurodegenerative disease. Probiotic biotherapies are known to create a healthy gut environment by balancing bacterial populations and promoting their favorable metabolic action. The microbiota and its respective metabolites communicate to the host through a series of biochemical and functional links thereby affecting host homeostasis and health. In particular, the gastrointestinal tract communicates with the central nervous system through the gut–brain axis to support neuronal development and maintenance while gut dysbiosis manifests in neurological disease. There are three basic mechanisms that mediate the communication between the gut and the brain: direct neuronal communication, endocrine signaling mediators and the immune system. Together, these systems create a highly integrated molecular communication network that link systemic imbalances with the development of neurodegeneration including insulin regulation, fat metabolism, oxidative markers and immune signaling. Age is a common factor in the development of neurodegenerative disease and probiotics prevent many harmful effects of aging such as decreased neurotransmitter levels, chronic inflammation, oxidative stress and apoptosis—all factors that are proven aggravators of neurodegenerative disease. Indeed patients with Parkinson’s and Alzheimer’s diseases have a high rate of gastrointestinal comorbidities and it has be proposed by some the management of the gut microbiota may prevent or alleviate the symptoms of these chronic diseases.
338 citations
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TL;DR: The study concludes that atmospheric depositions can elevate the levels of heavy metals in vegetables during marketing having potential health hazards to consumers.
338 citations
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TL;DR: Bacopa monniera (BM) induced a dose‐related increase in SOD, CAT and GPX activities, in all the brain regions investigated, after 14 and 21 days of drug administration, suggesting that the increase in oxidative free radical scavenging activity by BM may explain the cognition‐ facilitating action of BM.
Abstract: The effect of a standardized extract of Bacopa monniera Linn. was assessed on rat brain frontal cortical, striatal and hippocampal superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) activities, following administration for 7, 14 or 21 days. The effects induced by this extract (bacoside A content 82% +/- 0.5%), administered in doses of 5 and 10 mg/kg, orally, were compared with the effects induced by (-) deprenyl (2 mg/kg, p. o.) administered for the same time periods. Bacopa monniera (BM) induced a dose-related increase in SOD, CAT and GPX activities, in all the brain regions investigated, after 14 and 21 days of drug administration. On the contrary, deprenyl induced an increase in SOD, CAT and GPX activities in the frontal cortex and striatum, but not in the hippocampus, after treatment for 14 or 21 days. The results suggest that BM, like deprenyl, exhibits a significant antioxidant effect after subchronic administration which, unlike the latter, extends to the hippocampus as well. The results suggest that the increase in oxidative free radical scavenging activity by BM may explain, at least in part, the cognition- facilitating action of BM, recorded in Ayurvedic texts, and demonstrated experimentally and clinically.
335 citations
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TL;DR: In this article, the removal of Omega Chrome Red ME (a popular chrome dye) from its aqueous solutions by adsorption on a homogeneous mixture of fly ash and coal in different proportions has been carried out.
334 citations
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TL;DR: Isatin showed cardioinhibitory effect on frog heart, and hypotensive, respiratory depression and antidiuretic effects, and substituted indolinones showed antitubercular activity against M. tuberculosis H37Rv with MIC ranging from 10-20 microg mL(-1).
Abstract: Isatin is an endogenous compound identified in humans that possesses a wide range of biological activities. Isatin has anxiogenic, sedative, anticonvulsant activities and acts as a potent antagonist on atrial natriuretic peptide receptors in vitro. A series of p-substituted isatin semicarbazones have shown anticonvulsant activity in MES, scPTZ and scSTY tests. Various isatin-N-Mannich bases of isatin-3-thiosemicarbazones have shown antiviral and tuberculostatic activity. Methisazone is an effective compound against variola and vaccinia viruses. The N-dimethyl and morpholino derivative of 5-methyl isatin and trimethoprim exhibited an EC50 of more than 4.3 and 17.7 mg mL(-1), respectively. Isatin (3-o-nitrophenyl) hydrazone has shown activity against Walker carcinoma-256. Various substituted indolinones showed antitubercular activity against M. tuberculosis H37Rv with MIC ranging from 10-20 microg mL(-1). Isatin derivatives of Mannich bases had fibrinolytic, muscle relaxant, antiallergic, immunosuppressant, and antithrombotic activity. Isatin showed cardioinhibitory effect on frog heart, and hypotensive, respiratory depression and antidiuretic effects.
333 citations
Authors
Showing all 12110 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ashok Kumar | 151 | 5654 | 164086 |
Rajesh Kumar | 149 | 4439 | 140830 |
Prashant Shukla | 131 | 1341 | 85287 |
Sudhir Malik | 130 | 1669 | 98522 |
Vijay P. Singh | 106 | 1699 | 55831 |
Rakesh Agrawal | 105 | 668 | 107569 |
Gautam Sethi | 102 | 425 | 31088 |
Jens Christian Frisvad | 99 | 453 | 31760 |
Sandeep Kumar | 94 | 1563 | 38652 |
E. De Clercq | 90 | 774 | 30296 |
Praveen Kumar | 88 | 1339 | 35718 |
Shyam Sundar | 86 | 614 | 30289 |
Arvind Kumar | 85 | 876 | 33484 |
Padma Kant Shukla | 84 | 1232 | 35521 |
Brajesh K. Singh | 83 | 401 | 24101 |