Institution
Cardiff University
Education•Cardiff, United Kingdom•
About: Cardiff University is a education organization based out in Cardiff, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 34188 authors who have published 82643 publications receiving 3046531 citations. The organization is also known as: University of Cardiff & University College of South Wales and Monmouthshire.
Topics: Population, Context (language use), Catalysis, Galaxy, Poison control
Papers published on a yearly basis
Papers
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TL;DR: These findings provide the first in vivo evidence that Pink1 is detectable at basal levels and that basal mammalian mitophagy occurs independently of PINK1, and suggest multiple, yet-to-be-discovered pathways orchestrating mammalian mitochondrial integrity in a context-dependent fashion.
403 citations
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TL;DR: The hypothesis that pulse‐wave analysis (PWA) combined with provocative pharmacological testing might provide an alternative method for assessing vasomotor endothelial function in vivo is tested and it is shown that this methodology provides a simple, repeatable, noninvasive means of assessing endothelialfunction in vivo.
Abstract: Current methods for assessing vasomotor endothelial function are impractical for use in large studies. We tested the hypothesis that pulse-wave analysis (PWA) combined with provocative pharmacological testing might provide an alternative method. Radial artery waveforms were recorded and augmentation index (AIx) was calculated from derived aortic waveforms. Thirteen subjects received sublingual nitroglycerin (NTG), inhaled albuterol, or placebo. Twelve subjects received NTG, albuterol, and placebo separately during an infusion of N(G)-monomethyl-L-arginine (LNMMA) or norepinephrine. Twenty-seven hypercholesterolemic subjects and 27 controls received NTG followed by albuterol. Endothelial function was assessed by PWA and forearm blood flow in 27 subjects. Albuterol and NTG both significantly and repeatably reduced AIx (P<0.001). Only the response to albuterol was inhibited by LNMMA (-9.8+/-5.5% vs -4.7+/-2.7%; P=0.02). Baseline AIx was higher in the hypercholesterolemic subjects, who exhibited a reduced response to albuterol (P=0.02) but not to NTG when compared with matched controls. The responses to albuterol and acetylcholine were correlated (r=0.5, P=0.02). Consistent with an endothelium-dependent effect, the response to albuterol was substantially inhibited by LNMMA. Importantly, the response to albuterol was reduced in subjects with hypercholesterolemia and was correlated to that of intra-arterial acetylcholine. This methodology provides a simple, repeatable, noninvasive means of assessing endothelial function in vivo.
402 citations
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TL;DR: In this article, the authors examine mining company reports, revealing the language and constructs used by the mining industry to frame its responsibility to the environment and community and role in possible conflicts, and illustrate the issues and conflicts that arise between mining company operations and the environment.
Abstract: In response to widespread and increasing criticism, the mining industry has started to pay serious attention to its environmental and social impacts. This has recently manifested itself in the formulation of corporate social responsibility (CSR) policies and strategies and a proliferation of CSR, environmental, sustainability and community reporting. Several brief case studies are used to illustrate the issues and conflicts that arise between mining company operations and the environment and community, and how these have led to the development of corporate strategies to deal with environment and community issues. The paper then examines mining company reports, revealing the language and constructs used by the mining industry to frame its responsibility to the environment and community and role in possible conflicts. Companies need to better understand the complex nature of the communities in which they operate in order that suitably tailored strategies are developed. Copyright © 2004 John Wiley & Sons, Ltd and ERP Environment.
402 citations
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TL;DR: The aim is to fully understand the origins of the basic performance limits of known materials and to set the scene for new or improved materials which will breach those limits for new-generation transparent conducting materials, either oxides, or beyond oxides.
Abstract: Materials displaying the remarkable combination of high electrical conductivity and optical transparency already from the basis of many important technological applications, including flat panel displays, solar energy capture and other opto-electronic devices. Here we present the basic materials physics of these important materials centred on the nature of the doping process to generate n-type conductivity in transparent conducting oxides, the associated transition to the metallic (conducting) state and the detailed properties of the degenerate itinerant electron gas. The aim is to fully understand the origins of the basic performance limits of known materials and to set the scene for new or improved materials which will breach those limits for new-generation transparent conducting materials, either oxides, or beyond oxides.
401 citations
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TL;DR: It is found that, in line with earlier research, personal levels of social support contribute to a better self-reported health status and the study suggests that social capital is additionally important for people's health.
401 citations
Authors
Showing all 34629 results
Name | H-index | Papers | Citations |
---|---|---|---|
Rob Knight | 201 | 1061 | 253207 |
Stephen V. Faraone | 188 | 1427 | 140298 |
John J.V. McMurray | 178 | 1389 | 184502 |
David R. Williams | 178 | 2034 | 138789 |
John Hardy | 177 | 1178 | 171694 |
Dorret I. Boomsma | 176 | 1507 | 136353 |
Kay-Tee Khaw | 174 | 1389 | 138782 |
Anders Björklund | 165 | 769 | 84268 |
Edward T. Bullmore | 165 | 746 | 112463 |
Peter A. R. Ade | 162 | 1387 | 138051 |
Michael John Owen | 160 | 1110 | 135795 |
Gavin Davies | 159 | 2036 | 149835 |
Suvadeep Bose | 154 | 960 | 129071 |
Todd Adams | 154 | 1866 | 143110 |
John R. Hodges | 149 | 812 | 82709 |