Institution
Central Drug Research Institute
Facility•Lucknow, Uttar Pradesh, India•
About: Central Drug Research Institute is a facility organization based out in Lucknow, Uttar Pradesh, India. It is known for research contribution in the topics: Catalysis & Leishmania donovani. The organization has 4357 authors who have published 7257 publications receiving 143871 citations. The organization is also known as: Central Drug Research Institute, Lucknow & CDRI.
Topics: Catalysis, Leishmania donovani, Ring (chemistry), Aryl, Apoptosis
Papers published on a yearly basis
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TL;DR: The literature revealed that thyroid significantly impacts testicular development and that abnormal thyroid profile affects semen quality and male fertility by compromising testicular size, sperm motility and ejaculate volume.
Abstract: Since the identification of thyroid hormone receptors on the testes, thyroid has been suggested to have a significant impact on the male reproductive tract, spermatogenesis, and male fertility. Several research articles on the role of thyroid in spermatogenesis or male infertility have been published in the last three decades. We conducted an exhaustive literature search was conducted in order to create an up-to-date review of literature. This review aims to discuss the impact of thyroid on testicular development, spermatogenesis, hypo- or hyper- thyroidism and male infertility, and the management of thyroid related abnormal semen profile. The literature revealed that thyroid significantly impacts testicular development and that abnormal thyroid profile affects semen quality and male fertility by compromising testicular size, sperm motility and ejaculate volume. A clear link exists between thyroid hormones, testicular development and spermatogenesis. Thyroid disease negatively affects spermatogenesis and consequently may cause male infertility. In such cases, infertility is reversible, but more studies need to be conducted, especially in post-pubertal males to cement the current findings.
45 citations
TL;DR: Treatment with compounds decreasing apoptosis and increasing neuronal viability decreased the apoptotic neuronal number, however increased the neuronal viability, which could protect neurons from the ischemic injury.
45 citations
TL;DR: A series of novel benzocoumarin derivatives were synthesized and evaluated for their in vivo anti-dyslipidemic and in vitro antioxidant activities and preliminary screening indicates compound 4 as potential lead with significant lipid lowering and antioxidant activities.
45 citations
TL;DR: A series of marine alkaloid 8,9-dihydrocoscinamide B, its analogues and indolylglyoxylamide derivatives have been synthesized and screened for their in vitro antileishmanial activity profile in promastigotes and amastigote models.
45 citations
TL;DR: This work explores the hitherto unexplored reactivity of ynones as dipolarophiles with Bestmann–Ohira reagent to find di-ynones and molecules possessing both ynone and enone functionalities provide only monocycloaddition products.
45 citations
Authors
Showing all 4385 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Sanjay Kumar | 120 | 2052 | 82620 |
| John A. Katzenellenbogen | 95 | 691 | 36132 |
| Brajesh K. Singh | 83 | 401 | 24101 |
| Gaurav Sharma | 82 | 1244 | 31482 |
| Sudhir Kumar | 82 | 524 | 216349 |
| Pramod K. Srivastava | 79 | 390 | 27330 |
| Mohan K. Raizada | 75 | 473 | 21452 |
| Syed F. Ali | 71 | 446 | 18669 |
| Ravi Shankar | 66 | 672 | 19326 |
| Ramesh Chandra | 66 | 620 | 16293 |
| Manoj Kumar | 65 | 408 | 16838 |
| Manish Kumar | 61 | 1425 | 21762 |
| Anil Kumar Saxena | 58 | 310 | 10107 |
| Sanjay Krishna | 56 | 624 | 13731 |
| Naibedya Chattopadhyay | 56 | 242 | 9795 |