Dr. Hari Singh Gour University

About: Dr. Hari Singh Gour University is a education organization based out in Saugor, Madhya Pradesh, India. It is known for research contribution in the topics: Drug delivery & Computer science. The organization has 1120 authors who have published 1315 publications receiving 29511 citations. The organization is also known as: Dr Harisingh Gour Vishwavidyalaya & Sagar University.

Facile two-step electrochemical approach for the fabrication of nanostructured nickel oxyhydroxide/SS and its studies on oxygen evolution reaction

Abstract: The fabrication of an efficient electro-catalyst, made of non-precious metals, for oxygen evolution reaction (OER) is an exciting task. A simple cathodic deposition followed by electrochemical anodic activation has been proposed to prepare a potential electro-catalyst, amorphous nickel oxyhydroxide, on a stainless steel (SS) substrate wherein the whole fabrication procedure completes within a minute. The proposed protocol demonstrates good electrical contact between loosely packed amorphous nickel oxyhydroxide and SS substrate. The experimental results demonstrate cathodic deposition time significantly affect interfacial charge transfer resistance and in turn OER performance. Electrochemical results reveal OER proceeds through the formation of NiO2 intermediate. The amorphous nickel oxyhydroxide@SS fabricated using cathodic deposition time of 40 s followed by anodic activation of 15 s display the low overpotential of 330 mV@25 mA cm−2 (1.56 V vs. RHE) with long-term stability over 70 h.

Identification and characterization of cis-regulatory elements 'insulator and repressor' in PPARD gene.

Abstract: Aim Identification and functional characterization of cis-regulatory elements in human PPARD gene. Methods We used various bioinformatic tools on the publicly available human genome and Encyclopedia of DNA Elements databases to explore potential cis-regulatory elements in PPARD gene region. Results We predicted an insulator and an enhancer element in intron 2 of PPARD gene. Functional characterization using transient transfection, reporter assay and CTCF binding confirmed the insulator status. However, the predicted enhancer element showed repressor/silencer activity. Finally, we observed a potential interaction between these two cis-regulatory elements which is in agreement with 5C-Encyclopedia of DNA Elements data. Conclusion We report two functionally validated cis-regulatory elements in PPARD gene which will aid in understanding its regulation and role in metabolic functions.

Effect of Cryogenic Chill on Mechanical Properties of ASTM A 494 M Grade Nickel Based Alloy Metal Matrix Composites

Abstract: An investigation in the present research was made to fabricate and evaluate the microstructure and mechanical properties of metal matrix composites developed using cryogenically cooled copper chills, consisting of ASTM A 494 M grade nickel alloy matrix and garnet particles as the reinforcement. The particle's amount added ranges from 3 wt. % to 12 wt. % in steps of 3%. A stir casting process was used to fabricate the composite. The matrix alloy was melted in a casting furnace at around 1350˚C, the garnet particulates preheated to 600˚C, were introduced into the molten metal alloy. When pouring melt into mould, an arrangement was made at one end of the mould by placing copper chill blocks of varying thickness brazed with MS hallow block in which liquid nitrogen was circulated simultaneously for cryogenic effect. After solidification produced composite materials thus synthesized were examined for microstructural and mechanical properties as per ASTM standards.

Exudate Extraction from Fundus Images

Abstract: Diabetic Retinopathy is one of the medical conditions that a person suffering from Diabetes Mellitus may encounter. One of the major symptoms of this disorder is the presence of exudates in the retinal area of the eyes. In order to prevent blindness due to exudates, it becomes mandatory to cure them, and prevent their further accumulation. In recent years, research to automate diagnosis of this disease to assist the doctors for faster treatments is gaining importance. This paper reveals one such approach of extracting exudates from fundus images. The algorithm has been developed on MATLAB using Image Processing Toolbox. An accuracy of 81.6% was obtained for the novel approach explored in this paper.