Dr. Hari Singh Gour University

About: Dr. Hari Singh Gour University is a education organization based out in Saugor, Madhya Pradesh, India. It is known for research contribution in the topics: Drug delivery & Computer science. The organization has 1120 authors who have published 1315 publications receiving 29511 citations. The organization is also known as: Dr Harisingh Gour Vishwavidyalaya & Sagar University.

Engineering the MxZn1−xO (M = Al3+, Fe3+, Cr3+) nanoparticles for visible light-assisted catalytic mineralization of methylene blue dye using Taguchi design

Abstract: Here, we developed a sustainable solution to address the water pollution especially due to organic dye industries. Visible light-activated catalytic degradation of aqueous solution of methylene blue (MB) dye was studied by using trivalent metal ion-doped ZnO nanoparticles as a photocatalyst. The nano-photocatalysts were synthesized by microwave-irradiated solution combustion method using d-glucose as a fuel. Various experimental parameters were optimized using Taguchi design of experiment, analysis of variance (ANOVA) and Grey relational analysis in order to obtain potential ZnO photocatalyst. Using ANOVA and Grey relation analysis, the optimum conditions were estimated that 5.5 mol% Cr3+-doped ZnO with 4 min MW heating and calcined at 450 °C, which shows very impressing photo-catalytic property. The ANOVA confirms that the calcination temperature and dopants significantly influence crystallite size with contribution factor of 42.28% and 40.02%, respectively. The band gap energy of the photocatalyst was largely influenced by a type of dopant with contribution 85.77%. Grey relational grading indicates that the 5.5% Al3+ doping, 4 min MW heat treatment, 450 °C calcination temperature to get lesser band gap (3.05 eV) and smaller crystallite size (46.96 nm). As compared with other L9 orthogonal array, the degradation efficiency is found to be higher (89.31%) on the Grey theory predication result for MB dye. Herewith, we strongly confirm that the Taguchi design was an promising tool in engineering the ZnO photocatalyst with a very less experimental trials and cost saving approach.

Heparin-Tailored Biopolymeric Nanocarriers in Site-Specific Delivery: A Systematic Review.

Abstract: The combination of nanocarriers and biological molecules is of intense interest because of the synergistic properties offered by such newly synthesized composites. Heparin conjugated to nanomaterials has recently been investigated for its beneficial chemical and biological properties and its capacity to improve the biocompatibility of nanocarriers, increasing their performance in various biological applications. A variety of recent research combines heparin and nanomaterials for a myriad of uses. For example, heparin has been conjugated to the surface of magnetic and metallic nanoparticles, biodegradable and nondegradable synthetic polymers, nanocomposites, dendrimers, and the like. It has also been incorporated into nanocarriers. There are numerous possibilities for material composites and chemistries that incorporate heparin. These open the door for a range of novel applications, including improving anticoagulant activity, anticancer and antitubercular therapy, tissue engineering, and biosensors. This review examines the different possibilities of heparin-based nanocarriers and their medicinal or biological applications.

Cannabis: A Neurological Remedy or a Drug of Abuse in India.

Abstract: Since ancient times it is well documented the use of cannabis as a medicine due to its potential therapeutic activity while subsequently its use as drug of abuse spread increasingly. The present review sought to give an insight in the history of medical and recreational use of cannabis in India. Indian use of cannabis dates back to Vedic time, mostly for the ritualistic and religious purposed, as documented in the ancient literature. It was India that introduced the medical use of cannabis to neighboring countries. Nevertheless, in the same India medical use did not propagate due to religious and social stigma related to the plant itself. The pharmacoactive constituents of cannabis and their therapeutic values in Ayurvetic medicine have been here described together with the adverse effects they can cause with special reference to neurological ones, including withdrawal symptoms. Finally how cannabis made his en root to the India society has also been discussed.