École Normale Supérieure

About: École Normale Supérieure is a other organization based out in Paris, Île-de-France, France. It is known for research contribution in the topics: Population & Catalysis. The organization has 68439 authors who have published 99414 publications receiving 3092008 citations.

Lattice BGK Models for Navier-Stokes Equation

Abstract: We propose the lattice BGK models, as an alternative to lattice gases or the lattice Boltzmann equation, to obtain an efficient numerical scheme for the simulation of fluid dynamics. With a properly chosen equilibrium distribution, the Navier-Stokes equation is obtained from the kinetic BGK equation at the second-order of approximation. Compared to lattice gases, the present model is noise-free, has Galileian invariance and a velocity-independent pressure. It involves a relaxation parameter that influences the stability of the new scheme. Numerical simulations are shown to confirm the speed of sound and the shear viscosity.

Life with 6000 Genes

Abstract: The genome of the yeast Saccharomyces cerevisiae has been completely sequenced through a worldwide collaboration. The sequence of 12,068 kilobases defines 5885 potential protein-encoding genes, approximately 140 genes specifying ribosomal RNA, 40 genes for small nuclear RNA molecules, and 275 transfer RNA genes. In addition, the complete sequence provides information about the higher order organization of yeast's 16 chromosomes and allows some insight into their evolutionary history. The genome shows a considerable amount of apparent genetic redundancy, and one of the major problems to be tackled during the next stage of the yeast genome project is to elucidate the biological functions of all of these genes.

Biodiversity and Ecosystem Functioning: Current Knowledge and Future Challenges

Abstract: The ecological consequences of biodiversity loss have aroused considerable interest and controversy during the past decade. Major advances have been made in describing the relationship between species diversity and ecosystem processes, in identifying functionally important species, and in revealing underlying mechanisms. There is, however, uncertainty as to how results obtained in recent experiments scale up to landscape and regional levels and generalize across ecosystem types and processes. Larger numbers of species are probably needed to reduce temporal variability in ecosystem processes in changing environments. A major future challenge is to determine how biodiversity dynamics, ecosystem processes, and abiotic factors interact.

Magnesium gates glutamate-activated channels in mouse central neurones

Abstract: The responses of vertebrate neurones to glutamate involve at least three receptor types. One of these, the NMDA receptor (so called because of its specific activation by N-methyl-D-aspartate), induces responses presenting a peculiar voltage sensitivity. Above resting potential, the current induced by a given dose of glutamate (or NMDA) increases when the cell is depolarized. This is contrary to what is observed at classical excitatory synapses, and recalls the properties of 'regenerative' systems like the Na+ conductance of the action potential. Indeed, recent studies of L-glutamate, L-aspartate and NMDA-induced currents have indicated that the current-voltage (I-V) relationship can show a region of 'negative conductance' and that the application of these agonists can lead to a regenerative depolarization. Furthermore, the NMDA response is greatly potentiated by reducing the extracellular Mg2+ concentration [( Mg2+]o) below the physiological level (approximately 1 mM). By analysing the responses of mouse central neurones to glutamate using the patch-clamp technique, we have now found a link between voltage sensitivity and Mg2+ sensitivity. In Mg2+-free solutions, L-glutamate, L-aspartate and NMDA open cation channels, the properties of which are voltage independent. In the presence of Mg2+, the single-channel currents measured at resting potential are chopped in bursts and the probability of opening of the channels is reduced. Both effects increase steeply with hyperpolarization, thereby accounting for the negative slope of the I-V relationship of the glutamate response. Thus, the voltage dependence of the NMDA receptor-linked conductance appears to be a consequence of the voltage dependence of the Mg2+ block and its interpretation does not require the implication of an intramembrane voltage-dependent 'gate'.

Frequency-tuned salient region detection

Abstract: Detection of visually salient image regions is useful for applications like object segmentation, adaptive compression, and object recognition. In this paper, we introduce a method for salient region detection that outputs full resolution saliency maps with well-defined boundaries of salient objects. These boundaries are preserved by retaining substantially more frequency content from the original image than other existing techniques. Our method exploits features of color and luminance, is simple to implement, and is computationally efficient. We compare our algorithm to five state-of-the-art salient region detection methods with a frequency domain analysis, ground truth, and a salient object segmentation application. Our method outperforms the five algorithms both on the ground-truth evaluation and on the segmentation task by achieving both higher precision and better recall.