Henan Normal University

About: Henan Normal University is a education organization based out in Xinxiang, China. It is known for research contribution in the topics: Catalysis & Ionic liquid. The organization has 10863 authors who have published 11077 publications receiving 166773 citations.

Fluorescent probe for the imaging of superoxide and peroxynitrite during drug-induced liver injury.

Abstract: Drug-induced liver injury (DILI) is an important cause of potentially fatal liver disease. Herein, we report the development of a molecular probe (LW-OTf) for the detection and imaging of two biomarkers involved in DILI. Initially, primary reactive oxygen species (ROS) superoxide (O2˙-) selectively activates a near-infrared fluorescence (NIRF) output by generating fluorophore LW-OH. The C[double bond, length as m-dash]C linker of this hemicyanine fluorophore is subsequently oxidized by reactive nitrogen species (RNS) peroxynitrite (ONOO-), resulting in cleavage to release xanthene derivative LW-XTD, detected using two-photon excitation fluorescence (TPEF). An alternative fluorescence pathway can occur through cleavage of LW-OTf by ONOO- to non-fluorescent LW-XTD-OTf, which can react further with the second analyte O2˙- to produce the same LW-XTD fluorescent species. By combining NIRF and TPEF, LW-OTf is capable of differential and simultaneous detection of ROS and RNS in DILI using two optically orthogonal channels. Probe LW-OTf could be used to detect O2˙- or O2˙- and ONOO- in lysosomes stimulated by 2-methoxyestradiol (2-ME) or 2-ME and SIN-1 respectively. In addition, we were able to monitor the chemoprotective effects of tert-butylhydroxyanisole (BHA) against acetaminophen (APAP) toxicity in living HL-7702 cells. More importantly, TPEF and NIRF imaging confirmed an increase in levels of both O2˙- and ONOO- in mouse livers during APAP-induced DILI (confirmed by hematoxylin and eosin (H&E) staining).

Aerobic rice for water-saving agriculture. A review

Abstract: The increasing shortage of water resources has led to the development and adoption of aerobic rice system, which saves water input and increases water productivity by reducing water use during land preparation and limiting seepage, percolation, and evaporation. Aerobic rice also reduces labor requirement and greenhouse gaseous emission from rice field. In an aerobic rice system, the crop can be dry direct-seeded or transplanted and soils are kept aerobic throughout the growing season. Supplemental irrigation is applied as necessary. Aerobic rice cultivars are adapted to aerobic soils and have higher yield potential than traditional upland cultivars. Grain yields of 5–6 t ha−1 can be reached in aerobic rice system. However, yield decline or even complete failure of aerobic rice under continuous monocropping threatens the widespread adoption of aerobic rice technology. Here, we review research findings on possible causes responsible for yield decline of continuous aerobic rice. Our main findings are: (1) both biotic and abiotic factors are involved in the continuous cropping obstacle of aerobic rice; (2) recent research focused on abiotic factors related to the continuous cropping obstacle, such as soil pH increase, ammonia toxicity, and nutrient deficiencies; and (3) strategies which will help in mitigating the continuous cropping obstacle of aerobic rice include selection of new aerobic rice cultivars, nutrient management practice, crop rotation, and soil acidification. Identifying the causes responsible for continuous cropping obstacle of aerobic rice and adopting effective strategies are crucial to achieve sustainability of aerobic rice.

Search for hadronic transition chi(cJ) -> eta(c)pi(+)pi(-) and observation of chi(cJ) -> K(K)over-bar pi pi pi

Abstract: Hadronic transitions of chi(cJ) -> eta(c)pi(+)pi(-) (J = 0, 1, 2) are searched for using a sample of 1.06 x 10(8) psi(3686) events collected with the BESIII detector at the BEPCII storage ring. The eta(c) is reconstructed with (KSK +/-)-K-0 pi(-/+) and K+K-pi(0) final states. No signals are observed in any of the three chi(cJ) states in either eta(c) decay mode. At the 90% confidence level, the upper limits are determined to be B(chi(c0) -> eta(c)pi(+)pi(-)) eta(c)pi(+)pi(-)) eta(c)pi(+)pi(-)) eta(c)pi(+)pi(-)) is lower than the existing theoretical prediction by almost an order of magnitude. The branching fractions of chi(cJ) -> (KSK +/-)-K-0 pi(-/+)pi(+)pi(-), K+K-pi(+)pi(-)pi(0), omega K+K-, and phi pi(+)pi(-)pi(0) (J = 0, 1, 2) are measured for the first time. DOI: 10.1103/PhysRevD.87.012002