Indian Institute of Technology Bhubaneswar

About: Indian Institute of Technology Bhubaneswar is a education organization based out in Bhubaneswar, India. It is known for research contribution in the topics: Large Hadron Collider & Computer science. The organization has 1185 authors who have published 3132 publications receiving 48832 citations.

Alkyl chain-modified cyclometalated iridium complexes as tunable anticancer and imaging agents.

Abstract: Five mononuclear cyclometalated iridium complexes [1](PF6)-[5](PF6) were prepared using imidazole-based ligands of varying alkyl chain length. The complexes were characterised by various analytical techniques. The single crystal X-ray structures of [2](PF6), [3](PF6) and [4](PF6) revealed the expected distorted Oh structures around the metal centre; however, the chain length was found to play a crucial role in deciding the overall geometry. Theoretical investigations demonstrated that the HOMOs were mainly contributed by iridium and cyclometalated ligands, whereas the LUMOs were constituted from bpy/phen units. The complexes were found to be luminescent with a moderate emission quantum yield and lifetime in CH3CN. The in vitro growth inhibition assay of the complexes with a shorter alkyl chain ([4]+ and [5]+) displayed higher anticancer activity (IC50 50 μM), the complex [1]+ mainly accumulated near the cell membrane outside the cell and displayed a clear image of the cell membrane. The light microscopy images and western blot analysis reveal that complex [4]+ induced combined apoptosis and paraptosis. Thus, tuning the anticancer activity and cellular imaging property mediated by the alkyl chain would be of great importance and would be useful in anticancer research.

Size dependence of solvation structure and dynamics of ions in liquid n-methylacetamide: a molecular dynamics simulation study

Abstract: The solvation structure and dynamics of alkali metal (Li+, Na+, K+, Rb+, Cs+) and halide (F-, Cl-, Br-, I-) ions in liquid N-methylacetamide (NMA) are calculated at two different temperatures T = 313 K and 453 K, by using classical molecular dynamics simulations. We have also considered and some larger cations such as I+, Me4N+, and Et4N+ in this study to investigate the size dependence solvation structure and dynamics of ions in liquid NMA. With the increase of ion size, the self-diffusion coefficients of cations are found to increase and the maximum is observed at Me4N+, whereas for halide ions the increase of diffusion coefficient with ion size continues up to I- and no maximum is observed. However, the relative increase of the diffusion coefficients of larger ion compared to those of Li+ and F+ are found to be significantly higher at low temperature. Results are very good in agreement with experimental observation.

Influence of Clay Content and Montmorillonite Content on Swelling Behavior of Expansive Soils

Abstract: Swelling behavior of an expansive soil is principally governed by the contents of montmorillonite mineral and clay present in it. Studies attributing the swelling behavior to the presence of montmorillonite mineral are numerous, but defining an intricate relationship between clay and montmorillonite contents is almost nil. Thus, a comprehensive study is undertaken in this technical note that can aid in quantifying the exact influence of clay content (CC) and/or montmorillonite content in clay content (MCCC) on the swelling behavior. Interrelating CC and MCCC parameters is also another objective of the paper. Several numbers of different expansive soils were collected from different regions of India and experiments were conducted to quantify free swell index (FSI), CC, and MCCC. The results demonstrate that it is not only CC, but also MCCC has a remarkable influence on the swelling behavior. It has, particularly, been noticed from the interpretation of results that the role of mixed clay minerals, which is contrasting to a common belief that it is only MCCC primarily contributes to the swelling phenomenon and is least attempted by research fraternity, cannot be subdued. The study finds that between MCCC and CC, the former parameter seems to be more reliable for accurate prediction of swelling potential. The relationship between CC and MCCC seems to be linear up to MCCC of 40%. Beyond MCCC of 40%, CC apparently clustered between 30 and 60% only. MCCC, even though, found in minor quantity, exhibited significant influence on the FSI. The results presented in the study bear a practical significance for the safe design of foundation systems, buried pipelines, etc., in/on the expansive soils.

Evidence of a structure in K¯0Λc+ consistent with a charged Ξ c(2930) + , and updated measurement of B¯0→K¯0Λc+Λ¯c- at Belle: Belle Collaboration

Abstract: We report evidence for the charged charmed-strange baryon $$\Xi _{c}(2930)^+$$ with a signal significance of 3.9 $$\sigma $$ with systematic errors included. The charged $$\Xi _{c}(2930)^+$$ is found in its decay to $$K_{S}^{0} \Lambda _{c}^+$$ in the substructure of $$\bar{B}^{0} \rightarrow K^{0}_{S} \Lambda _{c}^{+} \bar{\Lambda }_{c}^{-}$$ decays. The measured mass and width are $$[2942.3 \pm 4.4 ({\mathrm{stat.}}) \pm {1.5}({\mathrm{syst.}})]$$ MeV/ $$c^{2}$$ and $$[14.8 \pm 8.8({\mathrm{stat.}}) \pm {2.5}({\mathrm{syst.}})]$$ MeV, respectively, and the product branching fraction is $$\mathcal{B}(\bar{B}^{0} \rightarrow \Xi _c(2930)^{+} \bar{\Lambda }_{c}^{-}) \mathcal{B}(\Xi _c(2930)^{+}\rightarrow \bar{K}^{0} \Lambda _{c}^{+})=[2.37 \pm 0.51 ({\mathrm{stat.}})\pm 0.31({\mathrm{syst.}})]\times 10^{-4}$$ . We also measure $$\mathcal{B}(\bar{B}^{0} \rightarrow \bar{K}^{0} \Lambda _{c}^{+} \bar{\Lambda }_{c}^{-}) = [3.99 \pm 0.76({\mathrm{stat.}}) \pm 0.51({\mathrm{syst.}})] \times 10^{-4}$$ with greater precision than previous experiments, and present the results of a search for the charmonium-like state Y(4660) and its spin partner, $$Y_{\eta }$$ , in the $$\Lambda _{c}^{+}\bar{\Lambda }_{c}^{-}$$ invariant mass spectrum. No clear signals of the Y(4660) or $$Y_{\eta }$$ are observed and the 90% credibility level (C.L.) upper limits on their production rates are determined. These measurements are obtained from a sample of $$(772\pm 11)\times 10^{6} B\bar{B}$$ pairs collected at the $$\Upsilon (4S)$$ resonance by the Belle detector at the KEKB asymmetric energy electron-positron collider.

Analysis of 3D signatures recorded using leap motion sensor

Abstract: Signature recognition is identifying the signature’s owner, whereas verification is the process to find whether a signature is genuine or forged. Though, both are important in the field of forensic sciences, however, verification is more important to banks and credit card companies. In this paper, we have proposed a methodology to analyze 3D signatures captured using Leap motion sensor. We have extended existing 2D features into 3D from raw signatures and applied well-known classifiers for recognition as well as verification. We have shown that the 3rd dimension, which essentially represents instantaneous pressure during writing, can improve the accuracy of the biometric systems. We have created a large dataset containing more than 2000 signatures registered by 100 volunteers using the Leap motion interface. This has been made available online for the research community. Our analysis shows that, the proposed 3D extension is better than its original 2D version. Recognition and verification accuracy have increased by 6.8% and 9.5%, respectively using k-NN. Similarly, accuracy has increased by 9.9% (recognition) and 6.5% (verification) when HMM is used as the classifier. Similar results have been recorded on benchmark datasets. A comparison with 2D tablet-stylus interface has been carried out which also supports our claims. We believe, Leap motion can be an alternative to the existing biometric setups.