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TL;DR: In this article, the authors numerically simulated a new circular micro heat sink (HS) used to cool electronic equipment (i.e., CPU), which contained Al2O3-water nanofluid (NF) at the concentration of 0.1%.
Abstract: The present study numerically simulates a new circular micro heat sink (HS) used to cool electronic equipment (i.e., CPU). The HS contained Al2O3-water nanofluid (NF) at the concentration of 0–1%. ...
15 citations
TL;DR: In this paper, the numerical prediction and comparison of thermal performance characteristics of a nuclear fuel element with and without cladding (bare fuel element) having non-uniform energy generation in axial direction is studied in detail.
15 citations
TL;DR: The present data suggests that ER stress and pro inflammatory cytokines serve as the major players in inducing glial cell dysfunction post gamma irradiation along with induction of genomic instability.
Abstract: Ionizing radiation induces various pathophysiological conditions by altering central nervous system (CNS) homeostasis, leading to neurodegenerative diseases. However, the potential effect of ionizing radiation response on cellular physiology in glial cells is unclear. In the present study, micronucleus test, comet assay, and RT-PCR were performed to investigate the potential effect of gamma radiation in cultured oligodendrocytes and astrocytes with respect to genomic instability, Endoplasmic Reticulum (ER) stress, and inflammation. Further, we studied the effect of alteration in ER stress specific gene expression in cortex post whole body radiation in mice. Results showed that exposure of gamma radiation of 2Gy in-vitro cultured astrocytes and oligodendrocytes and 7Gy in-vivo induced ER stress and Inflammation along with profuse DNA damage and Chromosomal abnormality. Additionally, we observed downregulation of myelin basic protein levels in cultured oligodendrocytes exposed to radiation. The present data suggests that ER stress and pro inflammatory cytokines serve as the major players in inducing glial cell dysfunction post gamma irradiation along with induction of genomic instability. Taken together, these results indicate that ER stress, DNA damage, and inflammatory pathways may be critical events leading to glial cell dysfunction and subsequent cell death following exposure to ionizing radiation.
15 citations
15 citations
TL;DR: In this article, numerical simulation of transient thermal and static structural analysis was performed sequentially with coupled thermo-structural method, and the numerical procedure of calculation was performed in the same manner as in this paper.
Abstract: In this paper, numerical simulation of transient thermal and static structural analysis was performed here sequentially with coupled thermo-structural method. Numerical procedure of calculation was...
14 citations
Authors
Showing all 298 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Shafiqur Rehman | 46 | 212 | 9437 |
| Asif Afzal | 23 | 156 | 1653 |
| Balladka Kunhanna Sarojini | 22 | 291 | 2659 |
| Mohammad Asif Hussain | 18 | 45 | 1665 |
| Sher Afghan Khan | 18 | 248 | 1782 |
| M.K. Ramis | 13 | 33 | 443 |
| Perveiz Khalid | 13 | 63 | 492 |
| M. Anaul Kabir | 12 | 20 | 477 |
| Zahid Ansari | 10 | 33 | 404 |
| P. R. Thyla | 10 | 44 | 293 |
| Mohammad Fazle Azeem | 10 | 44 | 421 |
| S. Pradeep | 9 | 19 | 893 |
| D. Senthilkumar | 9 | 17 | 336 |
| J. Mohan | 9 | 12 | 373 |
| A. D. Mohammed Samee | 9 | 12 | 254 |