P A College of Engineering

About: P A College of Engineering is a based out in . It is known for research contribution in the topics: Dihedral angle & Ring (chemistry). The organization has 298 authors who have published 594 publications receiving 4888 citations.

(E)-3-(3,4-Dimeth­oxy­phen­yl)-1-(2-hy­droxy­phen­yl)prop-2-en-1-one

Abstract: In the title compound, C17H16O4, the dihedral angle between the mean planes of the hy­droxy­phenyl and dimeth­oxy­phenyl rings is 5.9 (6)°. The mean plane of the prop-2-en-1-one group makes dihedral angles of 3.6 (0) and 2.6 (7)° with the hy­droxy­phenyl and dimeth­oxy­phenyl rings, respectively. An intra­molecular O—H⋯O hydrogen bond occurs. The crystal packing is stabilized by weak inter­molecular C—H⋯O contacts and π–π stacking inter­actions [centroid–centroid distance = 3.6571 (8) A].

Data Access Control and Secured Data Sharing Approach for Health Care Data in Cloud Environment

Abstract: One of the vital hitches in today's world of research is ensuring the security of the Cloud. This security can be ensured by inventing new techniques that may possibly help in safeguarding and assuring the optimal status of information in the cloud. Contents that are stored in the Cloud are majorly affected by the attempts made by illegitimate sources that are trying to access it. The security level of the contents that are stored in the cloud can be guaranteed by focusing on a task that helps in both securing and verifying the data. In order to manage the security level, (SE-KAC) which is also known as Scalable and Enhanced Key-Aggregate Cryptosystem was initiated in current research method. But this method of securing and sharing secret keys cannot be used in the stage of decryption. However this problem can be resolved in proposed method since it introduces sharing of the data securely using a method called Improved Diffie Hellman Key Exchange Algorithm (IDHKE). By introducing the Improved Diffie Hellman Key Exchange Algorithm, securely sharing the secret keys to the receivers of the data has been achieved. The secret key details can be exchanged securely using this method. By this means it makes sure its affirmations. Here the key is safely generated using one random prime number, a master secret key and parameter value. Intended for the secured and consistent access control limitation, an encryption which is attribute-based is used. The proposed method thus ensures the protected data transmission with exact and trustworthy validation.

Efficient and secure data hiding in video sequence with three layer security: an approach using chaos

Abstract: The fast development of communication and technology has created new challenges to transfer data securely. The techniques widely used to secure the data are cryptography and steganography. This paper presents a video steganography method to secure the information to be transmitted. Information transmitted can be an image, audio, text or video. This article presents a new technique that embeds data in the spatial domain of the cover video frame. The method employs chaotic maps to generate Random Positions (RP) to hide the information bits, random numbers for selecting the frames at which the information to be hidden and confusion order to encrypt the cover frame. The video frame is first selected based on Frame Selection (FS) is encrypted by applying Confusion Order (CO) and then embedding is carried out on the random positions generated. After embedding, the decrypted cover frame is replaced in a video sequence for transmission. This method provides three-level security in extracting the hidden secret information and also 25% of embedding capacity. Experimental outcomes (PSNR and payload) confirm that the method is competent.

Synthesis, Characterization, and Anticancer Studies of Some Pyrazole-Based Hybrid Heteroatomics

Abstract: Defined with a dual-mode of action, the hybrid molecule synthesis is an attractive strategy to endure the scientific challenges in drug discovery. Besides worthy development in cancer therapy, it is still a leading cause of death across the globe. Failure in terms of efficacy, selectivity and toxicity, the statistics of a potential drug to concrete the cancer is rather in bleak. In the present study, synthesized hybrid molecules were well characterized by spectroscopy techniques. The single-crystal X-ray crystallography study revealed the monoclinic crystal system of Dimethyl 1,4-dihydro-2,6-dimethyl-4-(3-(5-methyl-1-phenyl-1H-pyrazol-4-yl)-1H-pyr azol-4-yl)pyridine-3,5-dicarboxylate (5 b) with spacegroupC2/c. MTT assay provided the anticancer property of the compounds Diethyl1,4-dihydro-3,5-dimethyl-4-(3-(5-methyl-1-phenyl-1H-pyrazol-4-yl) -1H-pyrazol-4-yl)pyridine-2,6-dicarboxylate (5 a) and 5-methyl-1-phenyl-4-(4-(4,5-diphenyl-1H-imidazol-2-yl)-1H-pyrazol-3-yl)- 1H-pyrazole (6 a) against A549 cell lines with the IC(50)values of 42.79 mu M and 55.13 mu M respectively. The AO-EB staining assay for cell death analysis confirmed the selective action of both5 aand6 a. Further, molecular docking confirmed the effective binding with cyclin-dependent kinase (CDK2) protein, suggesting that the target compounds are remarkable inhibitors in dysregulating the CDK2 protein in cancer cells.

3-(6-methoxy-2-naphthyl)-1-(2-naphthyl)prop-2-en-1-one

Abstract: The title compound, C24H18O2, is a chalcone derivative The torsion angle between the mean planes of the two naphthalene groups is 54.41 (2)degrees.