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Institution

Stockholm University

EducationStockholm, Sweden
About: Stockholm University is a education organization based out in Stockholm, Sweden. It is known for research contribution in the topics: Population & Context (language use). The organization has 21052 authors who have published 62567 publications receiving 2725859 citations. The organization is also known as: University of Stockholm & Stockholms universitet.


Papers
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Journal ArticleDOI
TL;DR: The activities of some glutathione-metabolizing enzymes were observed to be 5-to 60-fold lower in lung tissue than in the liver, and that phenobarbital nor methylcholanthrene had a significant effect on the levels of reduced glutATHione in lung and liver.

3,842 citations

Journal ArticleDOI
TL;DR: In addition to the APOE locus (encoding apolipoprotein E), 19 loci reached genome-wide significance (P < 5 × 10−8) in the combined stage 1 and stage 2 analysis, of which 11 are newly associated with Alzheimer's disease.
Abstract: Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous studies; however, a large portion of the genetic risk for this disease remains unexplained. We conducted a large, two-stage meta-analysis of genome-wide association studies (GWAS) in individuals of European ancestry. In stage 1, we used genotyped and imputed data (7,055,881 SNPs) to perform meta-analysis on 4 previously published GWAS data sets consisting of 17,008 Alzheimer's disease cases and 37,154 controls. In stage 2, 11,632 SNPs were genotyped and tested for association in an independent set of 8,572 Alzheimer's disease cases and 11,312 controls. In addition to the APOE locus (encoding apolipoprotein E), 19 loci reached genome-wide significance (P < 5 × 10−8) in the combined stage 1 and stage 2 analysis, of which 11 are newly associated with Alzheimer's disease.

3,726 citations

Journal ArticleDOI
03 Nov 2006-Science
TL;DR: The authors analyzed local experiments, long-term regional time series, and global fisheries data to test how biodiversity loss affects marine ecosystem services across temporal and spatial scales, concluding that marine biodiversity loss is increasingly impairing the ocean's capacity to provide food, maintain water quality, and recover from perturbations.
Abstract: Human-dominated marine ecosystems are experiencing accelerating loss of populations and species, with largely unknown consequences. We analyzed local experiments, long-term regional time series, and global fisheries data to test how biodiversity loss affects marine ecosystem services across temporal and spatial scales. Overall, rates of resource collapse increased and recovery potential, stability, and water quality decreased exponentially with declining diversity. Restoration of biodiversity, in contrast, increased productivity fourfold and decreased variability by 21%, on average. We conclude that marine biodiversity loss is increasingly impairing the ocean's capacity to provide food, maintain water quality, and recover from perturbations. Yet available data suggest that at this point, these trends are still reversible.

3,672 citations


Authors

Showing all 21326 results

NameH-indexPapersCitations
Hongjie Dai197570182579
Hyun-Chul Kim1764076183227
Richard S. Ellis169882136011
Stanley B. Prusiner16874597528
Anders Björklund16576984268
Yang Yang1642704144071
Tomas Hökfelt158103395979
Bengt Winblad1531240101064
Zhenwei Yang150956109344
Marvin Johnson1491827119520
Jan-Åke Gustafsson147105898804
Markus Ackermann14661071071
Hans-Olov Adami14590883473
Markku Kulmala142148785179
Kjell Fuxe142147989846
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023158
2022537
20213,664
20203,602
20193,347
20183,092