Institution
Tata Memorial Hospital
Healthcare•Mumbai, India•
About: Tata Memorial Hospital is a healthcare organization based out in Mumbai, India. It is known for research contribution in the topics: Cancer & Breast cancer. The organization has 3187 authors who have published 4636 publications receiving 109143 citations.
Topics: Cancer, Breast cancer, Population, Radiation therapy, Carcinoma
Papers published on a yearly basis
Papers
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TL;DR: Data shows that studies with much larger number of patients are needed to exclude the possibility that histologic type may provide significant prognostic information in other stages of the disease, and selected World Health Organization histologic types are significantly associated with prognosis in stage III thymoma patients.
24 citations
TL;DR: The incidence of TMZ induced clinically significant neutropenia and thrombocytopenia was low in the patient population and gender, grade, leukocyte count, and serum creatinine were significant independent predictors of severe acute myelo-toxicity.
24 citations
TL;DR: It was determined that the methotrexate was extrinsically contaminated by reused needles, used for reconstitution and administration, which had been inadequately sterilized, and introduced single-use disposable needles, and no subsequent cases occurred.
24 citations
TL;DR: A patient with an unusual case of endodermal sinus (yolk sac) tumor arising in the vulva and presenting during pregnancy succumbed to her illness due to widespread pulmonary and pleural involvement within 11 months of onset of symptoms.
24 citations
TL;DR: Monitoring donor blood counts helps to avoid pheresis induced adverse events and high collection efficiency is a direct measure of an optimally functioning cell separator.
Abstract: Introduction: Platelet concentrate (PC) remains one of the most important support measures in thrombocytopenic patients. An efficient cell separator is a prerequisite for an optimally functioning apheresis setup. Donor blood count may undergo a temporary reduction after the procedure. Aim: The aim was to find the extent of reduction in donor blood count (hemoglobin, hematocrit, white blood cell, and platelet) after plateletpheresis and to evaluate the cell separator for collection efficiency, processing time, and leukoreduction. Study Design and Methods: Two hundred and thirty seven procedures performed on the Amicus (N = 121), Fenwal CS-3000 Plus (N = 50) and Cobe spectra (N = 66) in a one year period were evaluated. The procedures performed on the continuous flow centrifugation (CFC) cell separators and donor blood counts (pre and post donation) done were included in the study. Results: The percent reduction in hemoglobin (HB), hematocrit (HCT), white blood cell (WBC) and platelet count ((PLT ct) was 2.9, 3.1, 9, 30.7 (Mean, N = 237) respectively after the procedure. The post donation PLT ct reduced to <100x109/L (range 80-100) in five donors (N = 5/237, Amicus). The pre donation PLT ct in them was 150-200x109/L. Collection efficiency (percent) of Amicus (79.3) was better as compared to the other two machines (CS: 62.5, Cobe: 57.5). PC collected on Cobe spectra had <1x106 WBC. The donor pre donation PLT levels had a positive correlation to the product PLT yield (r = 0.30, P = 0.000). Conclusion: Monitoring donor blood counts helps to avoid pheresis induced adverse events. A cautious approach is necessary in donors whose pre donation PLT ct is 150-200x109/L. The main variable in PLT yield is donor PLT ct (pre donation). High collection efficiency is a direct measure of an optimally functioning cell separator.
24 citations
Authors
Showing all 3213 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Al B. Benson | 113 | 578 | 48364 |
| Keitaro Matsuo | 97 | 818 | 37349 |
| Ashish K. Jha | 87 | 503 | 30020 |
| Noopur Raje | 82 | 506 | 27878 |
| Muthupandian Ashokkumar | 76 | 511 | 20771 |
| Snehal G. Patel | 73 | 367 | 16905 |
| Rainu Kaushal | 58 | 232 | 16794 |
| Ajit S. Puri | 54 | 369 | 9948 |
| Jasbir S. Arora | 51 | 351 | 15696 |
| Sudeep Sarkar | 48 | 273 | 10087 |
| Ian T. Magrath | 47 | 107 | 8084 |
| Pankaj Chaturvedi | 45 | 325 | 15871 |
| Pradeep Kumar Gupta | 44 | 416 | 7181 |
| Shiv K. Gupta | 43 | 150 | 8911 |
| Kikkeri N. Naresh | 43 | 245 | 6264 |