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Institution

Tata Memorial Hospital

HealthcareMumbai, India
About: Tata Memorial Hospital is a healthcare organization based out in Mumbai, India. It is known for research contribution in the topics: Cancer & Breast cancer. The organization has 3187 authors who have published 4636 publications receiving 109143 citations.


Papers
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Journal ArticleDOI
TL;DR: On multivariate analysis, tumor depth and metastatic lymphadenopathy were found to be independent prognostic factors for disease-free survival, and advanced gingivobuccal cancers fail loco-regionally.

34 citations

Journal ArticleDOI
TL;DR: This dosimteric study suggests that comparison of orthogonal X-ray-based and CT-based HDR ICA planning is feasible, and ICRU rectal point dose correlates well with maximum rectal dose, while I CRU bladder point underestimates the maximum bladder dose.
Abstract: The purpose is to compare CT-based dosimetry with International Commission on Radiation Units and Measurements (ICRU 38) bladder and rectum reference points in patients of carcinoma of uterine cervix treated with intracavitary brachytherapy (ICA). Twenty-two consecutive patients were evaluated. Orthogonal radiographs and CT images were acquired and transferred to PLATO planning system. Bladder and rectal reference points were identified according to ICRU 38 recommendations. Dosimetry was carried out based on Manchester system. Patient treatment was done using 192 Iridium high dose rate (HDR) remote after-loading machine based on the conventional radiograph-based dosimetry. ICRU rectal and bladder point doses from the radiograph plans were compared with D 2 , dose received by 2 cm 3 of the organ receiving maximum dose from CT plan. V 2 , volume of organ receiving dose more than the ICRU reference point, was evaluated. The mean (±standard deviation) volume of rectum and bladder was 60 (±28) cm 3 and 138 (±41) cm 3 respectively. The mean reference volume in radiograph and CT plan was 105 (±7) cm 3 and 107 (±7) cm 3 respectively. It was found that 6 (±4) cm 3 of rectum and 16 (±10) cm 3 of bladder received dose more than the prescription dose. V 2 of rectum and bladder was 7 (±1.7) cm 3 and 20.8 (±6) cm 3 respectively. Mean D 2 of rectum and bladder was found to be 1.11 (±0.2) and 1.56 (±0.6) times the mean ICRU reference points respectively. This dosimteric study suggests that comparison of orthogonal X-ray-based and CT-based HDR ICA planning is feasible. ICRU rectal point dose correlates well with maximum rectal dose, while ICRU bladder point underestimates the maximum bladder dose.

34 citations

Journal ArticleDOI
TL;DR: Inverse planning offers good sparing of critical structures without compromising the target coverage and the average loading pattern of the whole patient cohort deviates from the standard Fletcher loading pattern.

34 citations

Journal ArticleDOI
TL;DR: The role of the critical care specialist has been unequivocally established in the management of severely ill patients throughout the world and many ICUs across the world function as "open ICUs," in which patients are admitted under a primary physician who has not been trained in critical care medicine.

33 citations


Authors

Showing all 3213 results

NameH-indexPapersCitations
Al B. Benson11357848364
Keitaro Matsuo9781837349
Ashish K. Jha8750330020
Noopur Raje8250627878
Muthupandian Ashokkumar7651120771
Snehal G. Patel7336716905
Rainu Kaushal5823216794
Ajit S. Puri543699948
Jasbir S. Arora5135115696
Sudeep Sarkar4827310087
Ian T. Magrath471078084
Pankaj Chaturvedi4532515871
Pradeep Kumar Gupta444167181
Shiv K. Gupta431508911
Kikkeri N. Naresh432456264
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20235
202232
2021223
2020244
2019206
2018239